Renal circulatory effects of adenosine in patients with chronic heart failure
Uri Elkayam, MD, FACCa,
Anilkumar Mehra, MDa,
Gregory Cohen, MDa,
Padmini Priya Tummala, MDa,
Ilyas Somer Karaalp, MDa,
Omar Rashid Wani, MDa and
Menahem Canetti, MDa
a Division of Cardiology, Department of Medicine, University of Southern California School of Medicine, Los Angeles, California, USA
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Figure 1 Effect of intrarenal artery administration of adenosine on mean group values of heart rate and mean renal artery pressure. BL = baseline.
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Figure 2 Doppler flow velocity signal measured in the renal artery at baseline and during adenosine infusion in one of the study patients. Velocity time interval (VTI) demonstrated a marked reduction, with only a small change in renal artery cross-sectional area (CSA).
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Figure 3 Individual and group mean values for Doppler-measured velocity–time integral (cm) (mean ± SE). BL = baseline. p = 0.001.
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Figure 4 Individual and group mean values for calculated RBF flow (ml/min per m2) (mean ± SE). BL = baseline. *p = 0.0002.
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Figure 5 Individual and group mean values for calculated renal vascular resistance (dynes·s·cm–5) (mean ± SE). BL = baseline. p = 0.0005.
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Figure 6 Individual and group mean values for renal artery cross-sectional area (cm2) (mean ± SE) measured by intravascular ultrasound. BL = baseline.
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