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Regulation of local tissue-type plasminogen activator release by endothelium-dependent and endothelium-independent agonists in human vasculature

^a Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
^b Division of Cardiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

View larger version (18K): [in a new window]   Figure 1 Net release of t-PA antigen (mean ± SE) across the forearm at baseline (B) and after the intrabrachial artery infusion of isoproterenol (ISO) (400 ng/min), methacholine (METH) (8 µg/min) and SNP (8 µg/min) (n = 15). Statistical comparison of respective stimulated values with baseline values is shown.