CLINICAL RESEARCH: CARDIAC IMAGING
Multislice Computed Tomographic Characteristics of Coronary Lesions in Acute Coronary Syndromes
Sadako Motoyama, MD, PhD*,*,
Takeshi Kondo, MD, PhD ,
Masayoshi Sarai, MD, PhD*,
Atsushi Sugiura, MD, PhD*,
Hiroto Harigaya, MD*,
Takahisa Sato, MD, PhD*,
Kaori Inoue, MD*,
Masanori Okumura, MD*,
Junichi Ishii, MD, PhD*,
Hirofumi Anno, MD, PhD ,
Renu Virmani, MD, FACC ,
Yukio Ozaki, MD, PhD*,
Hitoshi Hishida, MD, PhD* and
Jagat Narula, MD, PhD, FACC¶
* Department of Cardiology, Fujita Health University, Toyoake, Japan
Department of Cardiology, Takase Clinic, Takasaki, Japan
Department of Radiology, Fujita Health University, Toyoake, Japan
International Registry of Pathology, Gaithersburg, Maryland
¶ Division of Cardiology, University of California Irvine, Irvine, California. Dr. James E. Muller acted as the Guest Editor for this article
Manuscript received July 25, 2006;
revised manuscript received March 13, 2007,
accepted March 15, 2007.
* Reprint requests and correspondence: Dr. Sadako Motoyama, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan. (Email: sadakom{at}fujita-hu.ac.jp).
Objectives: To evaluate the feasibility of noninvasive assessment of the characteristics of disrupted atherosclerotic plaques, the authors interrogated the culprit lesions in acute coronary syndromes (ACS) by multislice computed tomography (CT).
Background: Disrupted atherosclerotic plaques responsible for ACS histopathologically demonstrate large lipid cores and positive vascular remodeling. It is expected that plaques vulnerable to rupture should bear similar imaging signatures by CT.
Methods: Either 0.5-mm x 16-slice or 64-slice CT was performed in 38 patients with ACS and compared with 33 patients with stable angina pectoris (SAP) before percutaneous coronary intervention. The coronary plaques in ACS and SAP were evaluated for the CT plaque characteristics, including vessel remodeling, consistency of noncalcified plaque (NCP <30 HU or 30 HU <NCP <150 HU), and spotty or large calcification.
Results: In the CT profile of culprit ACS and SAP lesions, the frequency of 30 HU <NCP <150 HU (100% vs. 100%, p = NS) was not different, and large calcification (22% vs. 55%, p = 0.004) was significantly more frequent in the stable lesions. Positive remodeling (87% vs. 12%, p < 0.0001), NCP <30 HU (79% vs. 9%, p < 0.0001), and spotty calcification (63% vs. 21%, p = 0.0005) were significantly more frequent in the ACS lesions. Presence of all 3 (i.e., positive remodeling, NCP <30 HU, and spotty calcification) showed a high positive predictive value, and absence of all 3 showed a high negative predictive value for the culprit plaques associated with ACS.
Conclusions: The CT characteristics of plaques associated with ACS include positive vascular remodeling, low plaque density, and spotty calcification. It is logical to presume that plaques vulnerable to rupture harbor similar characteristics.
|
Abbreviations and Acronyms
| | ACS = acute coronary syndrome | | CAG = coronary angiography | | CT = computed tomography | | ECG = electrocardiogram | | IVUS = intravascular ultrasound | | MSCT = multislice computed tomography | | NCP = noncalcified plaques | | NPV = negative predictive values | | NSTEMI = non–ST-segment elevation myocardial infarction | | PCI = percutaneous coronary intervention | | PPV = positive predictive value | | SAP = stable angina pectoris | | STEMI = ST-segment elevation myocardial infarction | | TCFA = thin cap fibroatheroma | | UAP = unstable angina pectoris |
|
Related Article
-
Inside This Issue of JACC
J. Am. Coll. Cardiol. 2007 50: A23-A24.
[Full Text]
[PDF]
This article has been cited by other articles:
|
|
|
|
 
M. J. Boogers, A. Broersen, J. E. van Velzen, F. R. de Graaf, H. M. El-Naggar, P. H. Kitslaar, J. Dijkstra, V. Delgado, E. Boersma, A. de Roos, et al.
Automated quantification of coronary plaque with computed tomography: comparison with intravascular ultrasound using a dedicated registration algorithm for fusion-based quantification
Eur. Heart J.,
January 26, 2012;
(2012)
ehr465v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
O. Gaemperli and P. A. Kaufmann
Hybrid CCTA/IVUS: breaking the traditional boundaries of coronary imaging
Eur. Heart J.,
January 26, 2012;
(2012)
ehs006v1.
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. R. Joshi, A. C. Lindsay, D. R. Obaid, E. Falk, and J. H. F. Rudd
Non-invasive imaging of atherosclerosis
Eur Heart J Cardiovasc Imaging,
January 24, 2012;
(2012)
jer319v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. L. Figueroa, S. S. Subramanian, R. C. Cury, Q. A. Truong, J. A. Gardecki, G. J. Tearney, U. Hoffmann, T. J. Brady, and A. Tawakol
Distribution of Inflammation Within Carotid Atherosclerotic Plaques With High-Risk Morphological Features: A Comparison Between Positron Emission Tomography Activity, Plaque Morphology, and Histopathology
Circ Cardiovasc Imaging,
January 1, 2012;
5(1):
69 - 77.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. J. de Feijter and K. Nieman
Failure of CT coronary imaging to identify plaque erosion: a resetting of expectations
Eur. Heart J.,
November 2, 2011;
32(22):
2736 - 2738.
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Ozaki, M. Okumura, T. F. Ismail, S. Motoyama, H. Naruse, K. Hattori, H. Kawai, M. Sarai, Y. Takagi, J. Ishii, et al.
Coronary CT angiographic characteristics of culprit lesions in acute coronary syndromes not related to plaque rupture as defined by optical coherence tomography and angioscopy
Eur. Heart J.,
November 2, 2011;
32(22):
2814 - 2823.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. J. Menezes, C. W. Kotze, O. Agu, T. Richards, J. Brookes, V. J. Goh, M. Rodriguez-Justo, R. Endozo, R. Harvey, S. W. Yusuf, et al.
Investigating Vulnerable Atheroma Using Combined 18F-FDG PET/CT Angiography of Carotid Plaque with Immunohistochemical Validation
J. Nucl. Med.,
November 1, 2011;
52(11):
1698 - 1703.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Lim, H. Shin, Y. Lee, J. Won Yoon, S. M. Kang, S. H. Choi, K. S. Park, H. C. Jang, S. I. Choi, and E. J. Chun
Effect of Metabolic Syndrome on Coronary Artery Stenosis and Plaque Characteristics as Assessed with 64-Detector Row Cardiac CT
Radiology,
November 1, 2011;
261(2):
437 - 445.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. H. Burdo, J. Lo, S. Abbara, J. Wei, M. E. DeLelys, F. Preffer, E. S. Rosenberg, K. C. Williams, and S. Grinspoon
Soluble CD163, a Novel Marker of Activated Macrophages, Is Elevated and Associated With Noncalcified Coronary Plaque in HIV-Infected Patients
The Journal of Infectious Disease,
October 15, 2011;
204(8):
1227 - 1236.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Nishio, Y. Ueda, K. Matsuo, M. Asai, T. Nemoto, A. Hirata, K. Kashiwase, and K. Kodama
Detection of disrupted plaques by coronary CT: comparison with angioscopy
Heart,
September 1, 2011;
97(17):
1397 - 1402.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Stolzmann, S. Subramanian, A. Abdelbaky, P. Maurovich-Horvat, H. Scheffel, A. Tawakol, and U. Hoffmann
Complementary Value of Cardiac FDG PET and CT for the Characterization of Atherosclerotic Disease
RadioGraphics,
September 1, 2011;
31(5):
1255 - 1269.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. S. Kristensen, K. F. Kofoed, J. T. Kuhl, W. B. Nielsen, M. B. Nielsen, and H. Kelbaek
Prognostic Implications of Nonobstructive Coronary Plaques in Patients With Non-ST-Segment Elevation Myocardial Infarction: A Multidetector Computed Tomography Study
J. Am. Coll. Cardiol.,
July 26, 2011;
58(5):
502 - 509.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Gauss, S. Achenbach, T. Pflederer, A. Schuhback, W. G. Daniel, and M. Marwan
Assessment of coronary artery remodelling by dual-source CT: a head-to-head comparison with intravascular ultrasound
Heart,
June 15, 2011;
97(12):
991 - 997.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Vancraeynest, A. Pasquet, V. Roelants, B. L. Gerber, and J.-L. J. Vanoverschelde
Imaging the Vulnerable Plaque
J. Am. Coll. Cardiol.,
May 17, 2011;
57(20):
1961 - 1979.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Korosoglou, S. Lehrke, D. Mueller, W. Hosch, H.-U. Kauczor, P. M. Humpert, E. Giannitsis, and H. A. Katus
Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque
Heart,
May 15, 2011;
97(10):
823 - 831.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Voros, S. Rinehart, Z. Qian, P. Joshi, G. Vazquez, C. Fischer, P. Belur, E. Hulten, and T. C. Villines
Coronary Atherosclerosis Imaging by Coronary CT Angiography: Current Status, Correlation With Intravascular Interrogation and Meta-Analysis
J. Am. Coll. Cardiol. Img.,
May 1, 2011;
4(5):
537 - 548.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J.-C. Tardif, F. Lesage, F. Harel, P. Romeo, and J. Pressacco
Imaging Biomarkers in Atherosclerosis Trials
Circ Cardiovasc Imaging,
May 1, 2011;
4(3):
319 - 333.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Rubin, H.-J. Chang, K. Nasir, R. S. Blumenthal, M. J. Blaha, E.-K. Choi, S.-A. Chang, Y. E. Yoon, E. J. Chun, S.-i. Choi, et al.
Association Between High-Sensitivity C-Reactive Protein and Coronary Plaque Subtypes Assessed by 64-Slice Coronary Computed Tomography Angiography in an Asymptomatic Population
Circ Cardiovasc Imaging,
May 1, 2011;
4(3):
201 - 209.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. A. Ambrose and S. Srikanth
Computed Tomographic Angiography for Localizing the Site of Plaque Disruption/Thrombus: Is Detection So Complex?
Circ Cardiovasc Imaging,
March 1, 2011;
4(2):
82 - 83.
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. D. Madder, K. M. Chinnaiyan, A. M. Marandici, and J. A. Goldstein
Features of Disrupted Plaques by Coronary Computed Tomographic Angiography: Correlates With Invasively Proven Complex Lesions
Circ Cardiovasc Imaging,
March 1, 2011;
4(2):
105 - 113.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. von Bary, M. Makowski, A. Preissel, A. Keithahn, A. Warley, E. Spuentrup, A. Buecker, J. Lazewatsky, R. Cesati, D. Onthank, et al.
MRI of Coronary Wall Remodeling in a Swine Model of Coronary Injury Using an Elastin-Binding Contrast Agent
Circ Cardiovasc Imaging,
March 1, 2011;
4(2):
147 - 155.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. T. D. Hoey
Coronary CT angiography: a paradigm shift in the evaluation of coronary artery disease?
Postgrad. Med. J.,
March 1, 2011;
87(1025):
163 - 164.
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Yerramasu, S. Venuraju, and A. Lahiri
Evolving role of cardiac CT in the diagnosis of coronary artery disease
Postgrad. Med. J.,
March 1, 2011;
87(1025):
180 - 188.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Arbab-Zadeh and J. Hoe
Quantification of Coronary Arterial Stenoses by Multidetector CT Angiography in Comparison With Conventional Angiography: Methods, Caveats, and Implications
J. Am. Coll. Cardiol. Img.,
February 1, 2011;
4(2):
191 - 202.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Ohashi, H. Yamamoto, J. Horiguchi, T. Kitagawa, E. Kunita, H. Utsunomiya, T. Oka, N. Kohno, and Y. Kihara
Association Between Visceral Adipose Tissue Area and Coronary Plaque Morphology Assessed by CT Angiography
J. Am. Coll. Cardiol. Img.,
September 1, 2010;
3(9):
908 - 917.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. S. Berman, V. Y. Cheng, and D. Dey
Not All Body Fat Weighs Equally in the Acceleration of Coronary Artery Disease
J. Am. Coll. Cardiol. Img.,
September 1, 2010;
3(9):
918 - 920.
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Inoue, S. Motoyama, M. Sarai, T. Sato, H. Harigaya, T. Hara, Y. Sanda, H. Anno, T. Kondo, N. D. Wong, et al.
Serial Coronary CT Angiography-Verified Changes in Plaque Characteristics as an End Point: Evaluation of Effect of Statin Intervention
J. Am. Coll. Cardiol. Img.,
July 1, 2010;
3(7):
691 - 698.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Achenbach and P. Raggi
Imaging of coronary atherosclerosis by computed tomography
Eur. Heart J.,
June 2, 2010;
31(12):
1442 - 1448.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. C. Tardif, P. L. L'Allier, R. Ibrahim, J. C. Gregoire, A. Nozza, M. Cossette, S. Kouz, M. A. Lavoie, J. Paquin, T. M. Brotz, et al.
Treatment With 5-Lipoxygenase Inhibitor VIA-2291 (Atreleuton) in Patients With Recent Acute Coronary Syndrome
Circ Cardiovasc Imaging,
May 1, 2010;
3(3):
298 - 307.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Phinikaridou, F. L. Ruberg, K. J. Hallock, Y. Qiao, N. Hua, J. Viereck, and J. A. Hamilton
In vivo Detection of Vulnerable Atherosclerotic Plaque by MRI in a Rabbit Model
Circ Cardiovasc Imaging,
May 1, 2010;
3(3):
323 - 332.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. N. Deliargyris
Intravascular Ultrasound Virtual Histology Derived Thin Cap Fibroatheroma: Now You See It, Now You Don't...
J. Am. Coll. Cardiol.,
April 13, 2010;
55(15):
1598 - 1599.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Uetani, T. Amano, A. Kunimura, S. Kumagai, H. Ando, K. Yokoi, T. Yoshida, B. Kato, M. Kato, N. Marui, et al.
The Association Between Plaque Characterization by CT Angiography and Post-Procedural Myocardial Infarction in Patients With Elective Stent Implantation
J. Am. Coll. Cardiol. Img.,
January 1, 2010;
3(1):
19 - 28.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J E van Velzen, J D Schuijf, F R de Graaf, G Nucifora, G Pundziute, J W Jukema, M J Schalij, L J Kroft, A de Roos, J H C Reiber, et al.
Plaque type and composition as evaluated non-invasively by MSCT angiography and invasively by VH IVUS in relation to the degree of stenosis
Heart,
December 15, 2009;
95(24):
1990 - 1996.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Kashiwagi, A. Tanaka, H. Kitabata, H. Tsujioka, H. Kataiwa, K. Komukai, T. Tanimoto, K. Takemoto, S. Takarada, T. Kubo, et al.
Feasibility of Noninvasive Assessment of Thin-Cap Fibroatheroma by Multidetector Computed Tomography
J. Am. Coll. Cardiol. Img.,
December 1, 2009;
2(12):
1412 - 1419.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
V. Dilsizian and J. Narula
Putting the Face to a Name: Concurrent Assessment of Vascular Morphology and Biology
J. Am. Coll. Cardiol. Img.,
October 1, 2009;
2(10):
1243 - 1244.
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Nagao, H. Matsuoka, H. Kawakami, H. Higashino, T. Mochizuki, M. Uemura, and S. Shigemi
Myocardial Ischemia in Acute Coronary Syndrome: Assessment Using 64-MDCT
Am. J. Roentgenol.,
October 1, 2009;
193(4):
1097 - 1106.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. J. Shaw and J. Narula
Risk Assessment and Predictive Value of Coronary Artery Disease Testing
J. Nucl. Med.,
August 1, 2009;
50(8):
1296 - 1306.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. J. Halpern
Triple-Rule-Out CT Angiography for Evaluation of Acute Chest Pain and Possible Acute Coronary Syndrome
Radiology,
August 1, 2009;
252(2):
332 - 345.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
O. Bayturan, E. M. Tuzcu, S. J. Nicholls, C. Balog, A. Lavoie, K. Uno, T. D. Crowe, W. A. Magyar, K. Wolski, S. Kapadia, et al.
Attenuated Plaque at Nonculprit Lesions in Patients Enrolled in Intravascular Ultrasound Atherosclerosis Progression Trials
J. Am. Coll. Cardiol. Intv.,
July 1, 2009;
2(7):
672 - 678.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. H.F. Rudd, F. Hyafil, and Z. A. Fayad
Inflammation Imaging in Atherosclerosis
Arterioscler Thromb Vasc Biol,
July 1, 2009;
29(7):
1009 - 1016.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M Marwan, D Ropers, T Pflederer, W G Daniel, and S Achenbach
Clinical characteristics of patients with obstructive coronary lesions in the absence of coronary calcification: an evaluation by coronary CT angiography
Heart,
July 1, 2009;
95(13):
1056 - 1060.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Motoyama, M. Sarai, H. Harigaya, H. Anno, K. Inoue, T. Hara, H. Naruse, J. Ishii, H. Hishida, N. D. Wong, et al.
Computed Tomographic Angiography Characteristics of Atherosclerotic Plaques Subsequently Resulting in Acute Coronary Syndrome
J. Am. Coll. Cardiol.,
June 30, 2009;
54(1):
49 - 57.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Braunwald
Noninvasive Detection of Vulnerable Coronary Plaques: Locking the Barn Door Before the Horse Is Stolen
J. Am. Coll. Cardiol.,
June 30, 2009;
54(1):
58 - 59.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Kawasaki, S. Koga, N. Koga, T. Noguchi, H. Tanaka, H. Koga, T. Serikawa, Y. Orita, S. Ikeda, T. Mito, et al.
Characterization of Hyperintense Plaque With Noncontrast T1-Weighted Cardiac Magnetic Resonance Coronary Plaque Imaging: Comparison With Multislice Computed Tomography and Intravascular Ultrasound
J. Am. Coll. Cardiol. Img.,
June 1, 2009;
2(6):
720 - 728.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. M. Botnar
Coronary Plaque Characterization by T1-Weighted Cardiac Magnetic Resonance
J. Am. Coll. Cardiol. Img.,
June 1, 2009;
2(6):
729 - 730.
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. Hyafil, J.-C. Cornily, J. H.F. Rudd, J. Machac, L. J. Feldman, and Z. A. Fayad
Quantification of Inflammation Within Rabbit Atherosclerotic Plaques Using the Macrophage-Specific CT Contrast Agent N1177: A Comparison with 18F-FDG PET/CT and Histology
J. Nucl. Med.,
June 1, 2009;
50(6):
959 - 965.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
U. Hoffmann and F. Bamberg
Is Computed Tomography Coronary Angiography the Most Accurate and Effective Noninvasive Imaging Tool to Evaluate Patients With Acute Chest Pain in the Emergency Department?: CT Coronary Angiography Is the Most Accurate and Effective Noninvasive Imaging Tool for Evaluating Patients Presenting With Chest Pain to the Emergency Department
Circ Cardiovasc Imaging,
May 1, 2009;
2(3):
251 - 263.
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Shaw and J. Narula
Bridging the Detection Gap Chasm of Risk: Where Can Computed Tomography Angiography Take Us?
J. Am. Coll. Cardiol. Img.,
April 1, 2009;
2(4):
524 - 526.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Kitagawa, H. Yamamoto, J. Horiguchi, N. Ohhashi, F. Tadehara, T. Shokawa, Y. Dohi, E. Kunita, H. Utsunomiya, N. Kohno, et al.
Characterization of noncalcified coronary plaques and identification of culprit lesions in patients with acute coronary syndrome by 64-slice computed tomography.
J. Am. Coll. Cardiol. Img.,
February 1, 2009;
2(2):
153 - 160.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. A. Goldstein
Coronary plaque characterization by computed tomographic angiography: present promise and future hope.
J. Am. Coll. Cardiol. Img.,
February 1, 2009;
2(2):
161 - 163.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. P. Carrigan, D. Nair, P. Schoenhagen, R. J. Curtin, Z. B. Popovic, S. Halliburton, S. Kuzmiak, R. D. White, S. D. Flamm, and M. Y. Desai
Prognostic utility of 64-slice computed tomography in patients with suspected but no documented coronary artery disease
Eur. Heart J.,
February 1, 2009;
30(3):
362 - 371.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. J. de Feyter, S. Achenbach, and K. Nieman
CHAPTER 6 Cardiovascular Computed Tomography
ESC Textbook of Cardiovascular Medicine,
January 1, 2009;
2(1):
med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Aldrovandi, F. Cademartiri, A. Menozzi, F. Ugo, D. Lina, E. Maffei, A. Palumbo, M. Fusaro, G. Crisi, and D. Ardissino
Evaluation of Coronary Atherosclerosis by Multislice Computed Tomography in Patients With Acute Myocardial Infarction and Without Significant Coronary Artery Stenosis: A Comparative Study With Quantitative Coronary Angiography
Circ Cardiovasc Imaging,
November 1, 2008;
1(3):
205 - 211.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. K. Min and L. J. Shaw
Noninvasive Diagnostic and Prognostic Assessment of Individuals With Suspected Coronary Artery Disease: Coronary Computed Tomographic Angiography Perspective
Circ Cardiovasc Imaging,
November 1, 2008;
1(3):
270 - 281.
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Pundziute, J. D. Schuijf, J. W. Jukema, I. Decramer, G. Sarno, P. K. Vanhoenacker, E. Boersma, J. H.C. Reiber, M. J. Schalij, W. Wijns, et al.
Evaluation of plaque characteristics in acute coronary syndromes: non-invasive assessment with multi-slice computed tomography and invasive evaluation with intravascular ultrasound radiofrequency data analysis
Eur. Heart J.,
October 1, 2008;
29(19):
2373 - 2381.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Schoenhagen and E. M. Tuzcu
Identifying patterns of atherosclerotic disease manifestation with coronary computed tomography. Impact on clinical management and outcome?
Eur. Heart J.,
October 1, 2008;
29(19):
2323 - 2324.
[Full Text]
[PDF]
|
|
|
|
|
|
|
A.J.H.A. Scholte, J.D. Schuijf, M.P. Stokkel, A. de Roos, and J.J. Bax
The Difficulty of Adequate Risk Stratification for Patients With Asymptomatic Diabetes
Circulation,
July 15, 2008;
118(3):
e65 - e68.
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Achenbach
Quantification of coronary artery stenoses by computed tomography.
J. Am. Coll. Cardiol. Img.,
July 1, 2008;
1(4):
472 - 474.
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Voros
Can Computed Tomography Angiography of the Coronary Arteries Characterize Atherosclerotic Plaque Composition?: Is the CAT (Scan) Out of the Bag?
J. Am. Coll. Cardiol. Intv.,
April 1, 2008;
1(2):
183 - 185.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. K. Min, L. Hofstra, S. V. Gurudevan, and M. D. Cerqueira
Imaging highlights of the American Heart Association 2007 scientific sessions.
J. Am. Coll. Cardiol. Img.,
March 1, 2008;
1(2):
252 - 262.
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Schroeder, S. Achenbach, F. Bengel, C. Burgstahler, F. Cademartiri, P. de Feyter, R. George, P. Kaufmann, A. F. Kopp, J. Knuuti, et al.
Cardiac computed tomography: indications, applications, limitations, and training requirements: Report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology
Eur. Heart J.,
February 2, 2008;
29(4):
531 - 556.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Williams, L. J. Shaw, P. Raggi, D. Morris, V. Vaccarino, S. T. Liu, S. R. Weinstein, T. P. Mosler, P. H. Tseng, F. R. Flores, et al.
Prognostic value of number and site of calcified coronary lesions compared with the total score.
J. Am. Coll. Cardiol. Img.,
January 1, 2008;
1(1):
61 - 69.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
