STATE-OF-THE-ART PAPER
Noninvasive Cardiac Imaging in Patients With Hypertrophic Cardiomyopathy
Sherif F. Nagueh, MD, FACC* and
John J. Mahmarian, MD, FACC
Department of Cardiology, The Methodist DeBakey Heart Center, The Methodist Hospital, Houston, Texas
Manuscript received February 2, 2006;
revised manuscript received June 28, 2006,
accepted July 30, 2006.
* Reprint requests and correspondence: Dr. Sherif F. Nagueh, Department of Cardiology, The Methodist DeBakey Heart Center, 6550 Fannin, Suite 677, Houston, Texas 77030. (Email: snagueh{at}tmh.tmc.edu).
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy and the most common cause of cardiac death in young athletes in the U.S. Noninvasive imaging plays an important role in detecting the disease, understanding its pathophysiology, and selecting as well as guiding appropriate therapy. In this review, we discuss the existing methodology with emphasis on current and emerging clinical applications in patients with HCM.
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Abbreviations and Acronyms
| | Aa = late diastolic velocity | | AV = atrioventricular | | Ea = early diastolic velocity | | EF = ejection fraction | | HCM = hypertrophic cardiomyopathy | | LA = left atrium/atrial | | LV = left ventricle/ventricular | | LVH = left ventricular hypertrophy | | LVOT = left ventricular outflow tract | | MR = mitral regurgitation | | RV = right ventricle/ventricular | | SAM = systolic anterior motion | | SPECT = single-photon emission computed tomography | | TD = tissue Doppler |
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