Advertisement

Click here for more guidelines.
2012 ACCF/ AATS/ SCAI/ STS Expert Consensus Document on Transcatheter Aortic Valve Replacement
ACCF/ SCAI/ STS/ AATS/ AHA/ ASNC/ HFSA/ SCCT 2012 Appropriate Use Criteria for Coronary Revascularization Focused Update
2012 ACCF/ AHA/ ACR/ SCAI/ SIR/ STS/ SVM/ SVN Key Data Elements and Definitions for Peripheral Atherosclerotic Vascular Disease

 
About JACC CME
Policy on Privacy and Confidentiality
Disclosures
Important Information
 

JACC Imaging Homepage JACC Interventions Homepage
Still not a subscriber to JACC Imaging or JACC Interventions?
Click here
to sign up now!

Submit Manuscripts
Author Information
Subscribe/Renew
Order Reprints
Email Alerts
Feedback
RSS Feed
CME
 
 

Cardiosmart
Cardiosource
CVN
Imaging Library
JACC Imaging
JACC Interventions
 
 

About the Journal
Editorial Board & Staff
 
CME Topic Collections Past Issues Search Current Issue Home
     

J Am Coll Cardiol, 2005; 46:807-814, doi:10.1016/j.jacc.2005.05.049 (Published online 24 August 2005).
© 2005 by the American College of Cardiology Foundation
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
j.jacc.2005.05.049v1
46/5/807    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Taylor, A. J.
Right arrow Articles by O'Malley, P. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Taylor, A. J.
Right arrow Articles by O'Malley, P. G.

PROGNOSTIC MARKERS IN CAD

Coronary Calcium Independently Predicts Incident Premature Coronary Heart Disease Over Measured Cardiovascular Risk Factors

Mean Three-Year Outcomes in the Prospective Army Coronary Calcium (PACC) Project

Allen J. Taylor, MD*, Jody Bindeman, BSN, Irwin Feuerstein, MD, Felix Cao, MS, Michael Brazaitis, MD and Patrick G. O'Malley, MD, MPH

Departments of Medicine and Radiology, Walter Reed Army Medical Center, Washington, DC

Manuscript received February 25, 2005; revised manuscript received April 29, 2005, accepted May 17, 2005.

* Reprint requests and correspondence: Dr. Allen J. Taylor, Cardiology Service, Walter Reed Army Medical Center, 6900 Georgia Avenue NW, Building 2, Room 3L28, Washington, DC 20307-5001 (Email: allen.taylor{at}na.amedd.army.mil).

OBJECTIVES: We sought to examine the independent predictive value of coronary artery calcium detection for coronary outcomes in a non-referred cohort of healthy men and women ages 40 to 50 years.

BACKGROUND: Existing studies have suggested that coronary calcium might have incremental predictive value for coronary outcomes above standard coronary risk factors. However, additional data from non-referred and younger populations are needed.

METHODS: Participants (n = 2,000; mean age 43 years) were evaluated with measured coronary risk variables and coronary calcium detected with electron beam tomography. Incident acute coronary syndromes and sudden cardiac death were ascertained via annual telephonic contacts, with follow-up (mean, 3.0 ± 1.4 years; range, 1 to 6 years) in 99.2% of the cohort.

RESULTS: Coronary calcium was found in 22.4% of men and 7.9% of women. A total of 9 acute events occurred in men at a mean age of 46 years, including 7 of 364 men with coronary calcium (1.95%) and 2 of 1,263 men without coronary calcium (0.16%; p < 0.0001 by log-rank). No events occurred in women. In these men, coronary calcium was associated with an 11.8-fold increased risk for incident coronary heart disease (CHD) (p = 0.002) in a Cox model controlling for the Framingham risk score. Among those with coronary artery calcification, the risk of coronary events increased incrementally across tertiles of coronary calcium severity (hazard ratio 4.3 per tertile). A family history of premature CHD was also predictive of incident events. The marginal cost effectiveness, assuming a 30% improvement in survival associated with primary prevention among at-risk men, was modeled to be $37,633 per quality-adjusted life year saved.

CONCLUSIONS: In young, asymptomatic men, the presence of coronary artery calcification provides substantial, cost-effective, independent prognostic value in predicting incident CHD that is incremental to measured coronary risk factors.

Abbreviations and Acronyms
  BMI = body mass index
  CAC = coronary artery calcium
  CHD = coronary heart disease
  CT = computed tomography
  EBCT = electron beam computed tomography
  FRS = Framingham risk score
  HDL = high-density lipoprotein
  LDL = low-density lipoprotein
  PACC = Prospective Army Coronary Calcium
  QALY = quality-adjusted life years




This article has been cited by other articles:


Home page
 J Am Coll Cardiol ImgHome page
T. M. Okwuosa, P. Greenland, G. L. Burke, J. Eng, M. Cushman, E. D. Michos, H. Ning, and D. M. Lloyd-Jones
Prediction of Coronary Artery Calcium Progression in Individuals With Low Framingham Risk Score: The Multi-Ethnic Study of Atherosclerosis
J. Am. Coll. Cardiol. Img., February 1, 2012; 5(2): 144 - 153.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart J Cardiovasc ImagingHome page
B. Bischoff, C. Kantert, T. Meyer, M. Hadamitzky, S. Martinoff, A. Schomig, and J. Hausleiter
Cardiovascular risk assessment based on the quantification of coronary calcium in contrast-enhanced coronary computed tomography angiography
Eur Heart J Cardiovasc Imaging, December 13, 2011; (2011) jer261v1.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
E. Lin and W. Hwang
Imaging Assessment of Cardiovascular Risk in Asymptomatic Adults
Am. J. Roentgenol., December 1, 2011; 197(6): W1046 - W1051.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. P. DeFilippis, M. J. Blaha, C. E. Ndumele, M. J. Budoff, D. M. Lloyd-Jones, R. L. McClelland, S. G. Lakoski, M. Cushman, N. D. Wong, R. S. Blumenthal, et al.
The Association of Framingham and Reynolds Risk Scores With Incidence and Progression of Coronary Artery Calcification in MESA (Multi-Ethnic Study of Atherosclerosis)
J. Am. Coll. Cardiol., November 8, 2011; 58(20): 2076 - 2083.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
B. J. H. van Kempen, S. Spronk, M. T. Koller, S. E. Elias-Smale, K. E. Fleischmann, M. A. Ikram, G. P. Krestin, A. Hofman, J. C. M. Witteman, and M. G. M. Hunink
Comparative effectiveness and cost-effectiveness of computed tomography screening for coronary artery calcium in asymptomatic individuals.
J. Am. Coll. Cardiol., October 11, 2011; 58(16): 1690 - 1701.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
P. Perrone-Filardi, S. Achenbach, S. Mohlenkamp, Z. Reiner, G. Sambuceti, J. D. Schuijf, E. Van der Wall, P. A. Kaufmann, J. Knuuti, S. Schroeder, et al.
Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: a position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology
Eur. Heart J., August 2, 2011; 32(16): 1986 - 1993.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. Blankstein, M. J. Budoff, L. J. Shaw, D. C. Goff Jr, J. F. Polak, J. Lima, R. S. Blumenthal, and K. Nasir
Predictors of Coronary Heart Disease Events Among Asymptomatic Persons With Low Low-Density Lipoprotein Cholesterol: MESA (Multi-Ethnic Study of Atherosclerosis)
J. Am. Coll. Cardiol., July 19, 2011; 58(4): 364 - 374.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol ImgHome page
M. Scharf, R. Bink, M. S. May, C. Hentschke, S. Achenbach, M. Uder, and M. M. Lell
High-Pitch Thoracic CT With Simultaneous Assessment of Coronary Arteries: Effect of Heart Rate and Heart Rate Variability on Image Quality and Diagnostic Accuracy
J. Am. Coll. Cardiol. Img., June 1, 2011; 4(6): 602 - 609.
[Abstract] [Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
P. Raggi, G. M. Chertow, P. U. Torres, B. Csiky, A. Naso, K. Nossuli, M. Moustafa, W. G. Goodman, N. Lopez, G. Downey, et al.
The ADVANCE study: a randomized study to evaluate the effects of cinacalcet plus low-dose vitamin D on vascular calcification in patients on hemodialysis
Nephrol. Dial. Transplant., April 1, 2011; 26(4): 1327 - 1339.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
T. J. Wang
Assessing the Role of Circulating, Genetic, and Imaging Biomarkers in Cardiovascular Risk Prediction
Circulation, February 8, 2011; 123(5): 551 - 565.
[Full Text] [PDF]

Home page
 CirculationHome page
Writing Committee Members, P. Greenland, J. S. Alpert, G. A. Beller, E. J. Benjamin, M. J. Budoff, Z. A. Fayad, E. Foster, M. A. Hlatky, J. M. Hodgson, et al.
2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Circulation, December 21, 2010; 122(25): e584 - e636.
[Full Text] [PDF]

Home page
 CirculationHome page
Writing Committee Members, P. Greenland, J. S. Alpert, G. A. Beller, E. J. Benjamin, M. J. Budoff, Z. A. Fayad, E. Foster, M. A. Hlatky, J. M. Hodgson, et al.
2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Circulation, December 21, 2010; 122(25): 2748 - 2764.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
P. Greenland, J. S. Alpert, G. A. Beller, E. J. Benjamin, M. J. Budoff, Z. A. Fayad, E. Foster, M. A. Hlatky, J. M. Hodgson, F. G. Kushner, et al.
2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the American Society of Echocardiography, American Society of Nuclear Cardiology, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance
J. Am. Coll. Cardiol., December 14, 2010; 56(25): e50 - e103.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
P. Greenland, J. S. Alpert, G. A. Beller, E. J. Benjamin, M. J. Budoff, Z. A. Fayad, E. Foster, M. A. Hlatky, J. M. Hodgson, F. G. Kushner, et al.
2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the American Society of Echocardiography, American Society of Nuclear Cardiology, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance
J. Am. Coll. Cardiol., December 14, 2010; 56(25): 2182 - 2199.
[Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
Z. Dastani and J. B. Richards
Is Coronary Artery Calcification at the Intersection of Vitamin D and Coronary Artery Disease?
Arterioscler Thromb Vasc Biol, December 1, 2010; 30(12): 2329 - 2330.
[Full Text] [PDF]

Home page
 RadiologyHome page
J. Shemesh, C. I. Henschke, D. Shaham, R. Yip, A. O. Farooqi, M. D. Cham, D. I. McCauley, M. Chen, J. P. Smith, D. M. Libby, et al.
Ordinal Scoring of Coronary Artery Calcifications on Low-Dose CT Scans of the Chest is Predictive of Death from Cardiovascular Disease
Radiology, November 1, 2010; 257(2): 541 - 548.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
P. M. Colletti, L. D. Dustin, N. D. Wong, J. E. Shriki, M. Kawakubo, S. P. Azen, and R. C. Detrano
Does Coronary Calcium Score Predict Future Cardiac Function? Association of Subclinical Atherosclerosis with Left Ventricular Systolic and Diastolic Dysfunction at MR Imaging in an Elderly Cohort
Radiology, October 1, 2010; 257(1): 64 - 70.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
A. D. Furtado, D. D. Adraktas, N. Brasic, S.- C. Cheng, K. Ordovas, W. S. Smith, M. R. Lewin, K. Chun, J. D. Chien, S. Schaeffer, et al.
The Triple Rule-Out for Acute Ischemic Stroke: Imaging the Brain, Carotid Arteries, Aorta, and Heart
AJNR Am. J. Neuroradiol., August 1, 2010; 31(7): 1290 - 1296.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
P. K. Shah
Screening Asymptomatic Subjects for Subclinical Atherosclerosis: Can We, Does It Matter, and Should We?
J. Am. Coll. Cardiol., July 6, 2010; 56(2): 98 - 105.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
J. M. Van Werkhoven, F. Cademartiri, S. Seitun, E. Maffei, A. Palumbo, C. Martini, G. Tarantini, L. J. Kroft, A. de Roos, A. C. Weustink, et al.
Diabetes: Prognostic Value of CT Coronary Angiography--Comparison with a Nondiabetic Population
Radiology, July 1, 2010; 256(1): 83 - 92.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
S. Achenbach and P. Raggi
Imaging of coronary atherosclerosis by computed tomography
Eur. Heart J., June 2, 2010; 31(12): 1442 - 1448.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol ImgHome page
A. P. DeFilippis, H. J. Kramer, R. Katz, N. D. Wong, A. G. Bertoni, J. Carr, M. J. Budoff, R. S. Blumenthal, and K. Nasir
Association Between Coronary Artery Calcification Progression and Microalbuminuria: The MESA Study
J. Am. Coll. Cardiol. Img., June 1, 2010; 3(6): 595 - 604.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
M. Hamer, K. O'Donnell, A. Lahiri, and A. Steptoe
Salivary cortisol responses to mental stress are associated with coronary artery calcification in healthy men and women
Eur. Heart J., February 2, 2010; 31(4): 424 - 429.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc GenetHome page
M. T. Scheuner, C. M. Setodji, J. S. Pankow, R. S. Blumenthal, and E. Keeler
General Cardiovascular Risk Profile Identifies Advanced Coronary Artery Calcium and Is Improved by Family History: The Multiethnic Study of Atherosclerosis
Circ Cardiovasc Genet, February 1, 2010; 3(1): 97 - 105.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
P. G. O'Malley
A Double Take on Serial Measurement of Coronary Artery Calcification
Arch Intern Med, December 14, 2009; 169(22): 2051 - 2052.
[Full Text] [PDF]

Home page
 Eur Heart JHome page
J. M. van Werkhoven, J. D. Schuijf, O. Gaemperli, J. W. Jukema, L. J. Kroft, E. Boersma, A. Pazhenkottil, I. Valenta, G. Pundziute, A. de Roos, et al.
Incremental prognostic value of multi-slice computed tomography coronary angiography over coronary artery calcium scoring in patients with suspected coronary artery disease
Eur. Heart J., November 1, 2009; 30(21): 2622 - 2629.
[Abstract] [Full Text] [PDF]

Home page
 ANN INTERN MEDHome page
U.S. Preventive Services Task Force
Using Nontraditional Risk Factors in Coronary Heart Disease Risk Assessment: U.S. Preventive Services Task Force Recommendation Statement
Ann Intern Med, October 6, 2009; 151(7): 474 - 482.
[Abstract] [Full Text] [PDF]

Home page
 ANN INTERN MEDHome page
M. Helfand, D. I. Buckley, M. Freeman, R. Fu, K. Rogers, C. Fleming, and L. L. Humphrey
Emerging Risk Factors for Coronary Heart Disease: A Summary of Systematic Reviews Conducted for the U.S. Preventive Services Task Force
Ann Intern Med, October 6, 2009; 151(7): 496 - 507.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
C. Uebleis, A. Becker, I. Griesshammer, P. Cumming, C. Becker, M. Schmidt, P. Bartenstein, and M. Hacker
Stable Coronary Artery Disease: Prognostic Value of Myocardial Perfusion SPECT in Relation to Coronary Calcium Scoring--Long-term Follow-up
Radiology, September 1, 2009; 252(3): 682 - 690.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. J. Budoff and K. Nasir
Reply
J. Am. Coll. Cardiol., August 4, 2009; 54(6): 574 - 575.
[Full Text] [PDF]

Home page
 J Am Coll Cardiol ImgHome page
A. Sarwar, L. J. Shaw, M. D. Shapiro, R. Blankstein, U. Hoffman, R. C. Cury, S. Abbara, T. J. Brady, M. J. Budoff, R. S. Blumenthal, et al.
Diagnostic and Prognostic Value of Absence of Coronary Artery Calcification
J. Am. Coll. Cardiol. Img., June 1, 2009; 2(6): 675 - 688.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol ImgHome page
M. Blaha, M. J. Budoff, L. J. Shaw, F. Khosa, J. A. Rumberger, D. Berman, T. Callister, P. Raggi, R. S. Blumenthal, and K. Nasir
Absence of Coronary Artery Calcification and All-Cause Mortality
J. Am. Coll. Cardiol. Img., June 1, 2009; 2(6): 692 - 700.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc ImagingHome page
P. Kaul and P. S. Douglas
Atherosclerosis Imaging: Prognostically Useful or Merely More of What We Know?
Circ Cardiovasc Imaging, March 1, 2009; 2(2): 150 - 160.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. M. van Werkhoven, J. D. Schuijf, O. Gaemperli, J. W. Jukema, E. Boersma, W. Wijns, P. Stolzmann, H. Alkadhi, I. Valenta, M. P.M. Stokkel, et al.
Prognostic Value of Multislice Computed Tomography and Gated Single-Photon Emission Computed Tomography in Patients With Suspected Coronary Artery Disease
J. Am. Coll. Cardiol., February 17, 2009; 53(7): 623 - 632.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. J. Budoff, K. Nasir, R. L. McClelland, R. Detrano, N. Wong, R. S. Blumenthal, G. Kondos, and R. A. Kronmal
Coronary Calcium Predicts Events Better With Absolute Calcium Scores Than Age-Sex-Race/Ethnicity Percentiles: MESA (Multi-Ethnic Study of Atherosclerosis)
J. Am. Coll. Cardiol., January 27, 2009; 53(4): 345 - 352.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc Qual OutcomesHome page
G. A. Diamond and S. Kaul
Cost, Effectiveness, and Cost-Effectiveness
Circ Cardiovasc Qual Outcomes, January 1, 2009; 2(1): 49 - 54.
[Full Text] [PDF]

Home page
 Eur Heart JHome page
M. M. Henneman, J. D. Schuijf, J. M. van Werkhoven, G. Pundziute, E. E. van der Wall, J. W. Jukema, and J. J. Bax
Multi-slice computed tomography coronary angiography for ruling out suspected coronary artery disease: what is the prevalence of a normal study in a general clinical population?
Eur. Heart J., August 2, 2008; 29(16): 2006 - 2013.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
E.-K. Choi, S. I. Choi, J. J. Rivera, K. Nasir, S.-A. Chang, E. J. Chun, H.-K. Kim, D.-J. Choi, R. S. Blumenthal, and H.-J. Chang
Coronary Computed Tomography Angiography as a Screening Tool for the Detection of Occult Coronary Artery Disease in Asymptomatic Individuals
J. Am. Coll. Cardiol., July 29, 2008; 52(5): 357 - 365.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
E. R. Brown, R. A. Kronmal, D. A. Bluemke, A. D. Guerci, J. J. Carr, J. Goldin, and R. Detrano
Coronary Calcium Coverage Score: Determination, Correlates, and Predictive Accuracy in the Multi-Ethnic Study of Atherosclerosis
Radiology, June 1, 2008; 247(3): 669 - 675.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
J. R. Burt, C. Iribarren, J. M. Fair, L. C. Norton, M. Mahbouba, G. D. Rubin, M. A. Hlatky, A. S. Go, S. P. Fortmann, and for the Atherosclerotic Disease, Vascular Function
Incidental Findings on Cardiac Multidetector Row Computed Tomography Among Healthy Older Adults: Prevalence and Clinical Correlates
Arch Intern Med, April 14, 2008; 168(7): 756 - 761.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. J. Taylor, J. Bindeman, I. Feuerstein, T. Le, K. Bauer, C. Byrd, H. Wu, and P. G. O'Malley
Community-Based Provision of Statin and Aspirin After the Detection of Coronary Artery Calcium Within a Community-Based Screening Cohort
J. Am. Coll. Cardiol., April 8, 2008; 51(14): 1337 - 1341.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
P. Greenland and R. O. Bonow
How Low-Risk Is a Coronary Calcium Score of Zero?: The Importance of Conditional Probability
Circulation, April 1, 2008; 117(13): 1627 - 1629.
[Full Text] [PDF]

Home page
 CirculationHome page
I. Gottlieb and J. A. C. Lima
Screening High-Risk Patients With Computed Tomography Angiography
Circulation, March 11, 2008; 117(10): 1318 - 1332.
[Full Text] [PDF]

Home page
 CirculationHome page
C. M. Kramer
All High-Risk Patients Should Not Be Screened With Computed Tomographic Angiography
Circulation, March 11, 2008; 117(10): 1333 - 1339.
[Full Text] [PDF]

Home page
 Eur Heart JHome page
S. Schroeder, S. Achenbach, F. Bengel, C. Burgstahler, F. Cademartiri, P. de Feyter, R. George, P. Kaufmann, A. F. Kopp, J. Knuuti, et al.
Cardiac computed tomography: indications, applications, limitations, and training requirements: Report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology
Eur. Heart J., February 2, 2008; 29(4): 531 - 556.
[Abstract] [Full Text] [PDF]

Home page
 IBMS BoneKEyHome page
T. Winzenberg and G. Jones
Recommended Calcium Intakes in Children: Have We Set the Bar Too High?
IBMS BoneKEy, February 1, 2008; 5(2): 59 - 68.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
S. Stern
Are We Getting Nearer to Screening for Atherosclerosis?
Circulation, January 1, 2008; 117(1): 122 - 126.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
K. Nasir, L. J. Shaw, S. T. Liu, S. R. Weinstein, T. R. Mosler, P. R. Flores, F. R. Flores, P. Raggi, D. S. Berman, R. S. Blumenthal, et al.
Ethnic Differences in the Prognostic Value of Coronary Artery Calcification for All-Cause Mortality
J. Am. Coll. Cardiol., September 4, 2007; 50(10): 953 - 960.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
K. Nasir, M. J. Budoff, N. D. Wong, M. Scheuner, D. Herrington, D. K. Arnett, M. Szklo, P. Greenland, and R. S. Blumenthal
Family History of Premature Coronary Heart Disease and Coronary Artery Calcification: Multi-Ethnic Study of Atherosclerosis (MESA)
Circulation, August 7, 2007; 116(6): 619 - 626.
[Abstract] [Full Text] [PDF]

Home page
 European Journal of Cardiovascular Prevention & RehabilitationHome page
N. Dragano, P. E. Verde, S. Moebus, A. Stang, A. Schmermund, U. Roggenbuck, S. Mohlenkamp, R. Peter, K.-H. Jockel, R. Erbel, et al.
Subclinical coronary atherosclerosis is more pronounced in men and women with lower socio-economic status: associations in a population-based study Coronary atherosclerosis and social status
European Journal of Cardiovascular Prevention & Rehabilitation, August 1, 2007; 14(4): 568 - 574.
[Abstract] [Full Text] [PDF]

Home page
 British Journal of Diabetes & Vascular DiseaseHome page
P. Raggi and A. Bellasi
Review: Imaging to assess effect of medical therapy in patients with diabetes mellitus
The British Journal of Diabetes & Vascular Disease, July 1, 2007; 7(4): 157 - 164.
[Abstract] [PDF]

Home page
 J Am Coll CardiolHome page
O. Ben-Yehuda
High-Sensitivity C-Reactive Protein in Every Chart?: The Use of Biomarkers in Individual Patients
J. Am. Coll. Cardiol., May 29, 2007; 49(21): 2139 - 2141.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
R. A. Kronmal, R. L. McClelland, R. Detrano, S. Shea, J. A. Lima, M. Cushman, D. E. Bild, and G. L. Burke
Risk Factors for the Progression of Coronary Artery Calcification in Asymptomatic Subjects: Results From the Multi-Ethnic Study of Atherosclerosis (MESA)
Circulation, May 29, 2007; 115(21): 2722 - 2730.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
K. Nasir, M. J. Budoff, L. J. Shaw, and R. S. Blumenthal
Value of Multislice Computed Tomography Coronary Angiography in Suspected Coronary Artery Disease
J. Am. Coll. Cardiol., May 22, 2007; 49(20): 2070 - 2071.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. D. Guerci
The Prognostic Accuracy of Coronary Calcification
J. Am. Coll. Cardiol., May 8, 2007; 49(18): 1871 - 1873.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. J. Budoff, L. J. Shaw, S. T. Liu, S. R. Weinstein, T. P. Mosler, P. H. Tseng, F. R. Flores, T. Q. Callister, P. Raggi, and D. S. Berman
Long-Term Prognosis Associated With Coronary Calcification: Observations From a Registry of 25,253 Patients
J. Am. Coll. Cardiol., May 8, 2007; 49(18): 1860 - 1870.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
J. J. Bax, S. E. Inzucchi, R. O. Bonow, J. D. Schuijf, M. R. Freeman, E. J. Barrett, and on behalf of the Global Dialogue Group for the Eva
Cardiac Imaging for Risk Stratification in Diabetes
Diabetes Care, May 1, 2007; 30(5): 1295 - 1304.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
P. Greenland, R. O. Bonow, B. H. Brundage, M. J. Budoff, M. J. Eisenberg, S. M. Grundy, M. S. Lauer, W. S. Post, P. Raggi, R. F. Redberg, et al.
ACCF/AHA 2007 Clinical Expert Consensus Document on Coronary Artery Calcium Scoring By Computed Tomography in Global Cardiovascular Risk Assessment and in Evaluation of Patients With Chest Pain: A Report of the American College of Cardiology Foundation Clinical Expert Consensus Task Force (ACCF/AHA Writing Committee to Update the 2000 Expert Consensus Document on Electron Beam Computed Tomography) Developed in Collaboration With the Society of Atherosclerosis Imaging and Prevention and the Society of Cardiovascular Computed Tomography
J. Am. Coll. Cardiol., January 23, 2007; 49(3): 378 - 402.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
G. Pundziute, J. D. Schuijf, J. W. Jukema, E. Boersma, A. de Roos, E. E. van der Wall, and J. J. Bax
Prognostic Value of Multislice Computed Tomography Coronary Angiography in Patients With Known or Suspected Coronary Artery Disease
J. Am. Coll. Cardiol., January 2, 2007; 49(1): 62 - 70.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. J. Gibbons, P. A. Araoz, and E. E. Williamson
The Year in Cardiac Imaging
J. Am. Coll. Cardiol., December 5, 2006; 48(11): 2324 - 2339.
[Full Text] [PDF]

Home page
 Arch Intern MedHome page
S. S. Gidding, C. A. McMahan, H. C. McGill, L. A. Colangelo, P. J. Schreiner, O. D. Williams, and K. Liu
Prediction of Coronary Artery Calcium in Young Adults Using the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Risk Score: The CARDIA Study
Arch Intern Med, November 27, 2006; 166(21): 2341 - 2347.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
M. J. Budoff, S. Achenbach, R. S. Blumenthal, J. J. Carr, J. G. Goldin, P. Greenland, A. D. Guerci, J. A.C. Lima, D. J. Rader, G. D. Rubin, et al.
Assessment of Coronary Artery Disease by Cardiac Computed Tomography: A Scientific Statement From the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology
Circulation, October 17, 2006; 114(16): 1761 - 1791.
[Full Text] [PDF]

Home page
 Postgrad. Med. J.Home page
T. K Mittal, M. Barbir, and M. Rubens
Role of computed tomography in risk assessment for coronary heart disease.
Postgrad. Med. J., October 1, 2006; 82(972): 664 - 671.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
J. R. Crouse III
Thematic review series: Patient-Oriented Research. Imaging atherosclerosis: state of the art
J. Lipid Res., August 1, 2006; 47(8): 1677 - 1699.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. J. Budoff
Prevalence of Soft Plaque Detection With Computed Tomography
J. Am. Coll. Cardiol., July 18, 2006; 48(2): 319 - 321.
[Full Text] [PDF]

Home page
 JNMHome page
D. S. Berman, R. Hachamovitch, L. J. Shaw, J. D. Friedman, S. W. Hayes, L. E.J. Thomson, D. S. Fieno, G. Germano, N. D. Wong, X. Kang, et al.
Roles of Nuclear Cardiology, Cardiac Computed Tomography, and Cardiac Magnetic Resonance: Noninvasive Risk Stratification and a Conceptual Framework for the Selection of Noninvasive Imaging Tests in Patients with Known or Suspected Coronary Artery Disease
J. Nucl. Med., July 1, 2006; 47(7): 1107 - 1118.
[Abstract] [Full Text] [PDF]

Home page
 CJASNHome page
S. M. Moe and G. M. Chertow
The Case against Calcium-Based Phosphate Binders
Clin. J. Am. Soc. Nephrol., July 1, 2006; 1(4): 697 - 703.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
X. Qin, M. A. Corriere, L. M. Matrisian, and R. J. Guzman
Matrix Metalloproteinase Inhibition Attenuates Aortic Calcification
Arterioscler Thromb Vasc Biol, July 1, 2006; 26(7): 1510 - 1516.
[Abstract] [Full Text] [PDF]

Home page
 Arch Intern MedHome page
P. G. O'Malley
Atherosclerosis imaging of asymptomatic individuals: is the sales cart before the evidence horse?
Arch Intern Med, May 22, 2006; 166(10): 1065 - 1068.
[Full Text] [PDF]

Home page
 Psychosom. Med.Home page
T. T. Lewis, S. A. Everson-Rose, L. H. Powell, K. A. Matthews, C. Brown, K. Karavolos, K. Sutton-Tyrrell, E. Jacobs, and D. Wesley
Chronic Exposure to Everyday Discrimination and Coronary Artery Calcification in African-American Women: The SWAN Heart Study
Psychosom Med, May 1, 2006; 68(3): 362 - 368.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
L. L. Yan, K. Liu, M. L. Daviglus, L. A. Colangelo, C. I. Kiefe, S. Sidney, K. A. Matthews, and P. Greenland
Education, 15-year risk factor progression, and coronary artery calcium in young adulthood and early middle age: the Coronary Artery Risk Development in Young Adults study.
JAMA, April 19, 2006; 295(15): 1793 - 1800.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
L. J. Shaw, P. Raggi, T. Q. Callister, and D. S. Berman
Prognostic value of coronary artery calcium screening in asymptomatic smokers and non-smokers
Eur. Heart J., April 2, 2006; 27(8): 968 - 975.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
D. V. Anand, E. Lim, D. Hopkins, R. Corder, L. J. Shaw, P. Sharp, D. Lipkin, and A. Lahiri
Risk stratification in uncomplicated type 2 diabetes: prospective evaluation of the combined use of coronary artery calcium imaging and selective myocardial perfusion scintigraphy
Eur. Heart J., March 2, 2006; 27(6): 713 - 721.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. A. Rumberger
The Promise of Quantitative Computed Tomography Coronary Angiography and Noninvasive Segmental Coronary Plaque Quantification: Pushing the "Edge"
J. Am. Coll. Cardiol., February 7, 2006; 47(3): 678 - 680.
[Full Text] [PDF]

Home page
 CirculationHome page
L. H. Kuller
Prevention of Coronary Heart Disease and the National Cholesterol Education Program
Circulation, February 7, 2006; 113(5): 598 - 600.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. N. DeMaria, O. Ben-Yehuda, D. Berman, G. K. Feld, G. S. Ginsburg, B. H. Greenberg, W. Y.W. Lew, D. Sahn, and S. Tsimikas
Highlights of the Year in JACC 2005
J. Am. Coll. Cardiol., January 3, 2006; 47(1): 184 - 202.
[Full Text] [PDF]


 
  CME Topic Collections Past Issues Search Current Issue Home

Advertisement