Successful reversal by chelation therapy of congestive cardiomyopathy due to iron overload
PS Rahko,
R Salerni,
and
BF Uretsky
A patient who developed severe iron overload cardiomyopathy is described. Venesection could not be performed because the patient had chronic anemia. Deferoxamine mesylate, a chelating agent, was administered daily for more than 2 years and produced significant improvement in ventricular function which was associated with a biopsy-proven decrease in myocardial iron stores. This is the first reported case in which a severe cardiomyopathy due to iron overload was reversed by chelation therapy alone.
This article has been cited by other articles:
|
|
|
|
 
E. M. Walker Jr., R. G. Morrison, L. Dornon, J. P. Laurino, S. M. Walker, M. Studeny, P. S. Wehner, K. M. Rice, M. Wu, and E. R. Blough
Acetaminophen Combinations Protect Against Iron-Induced Cardiac Damage in Gerbils
Ann. Clin. Lab. Sci.,
January 1, 2009;
39(4):
378 - 385.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. T. Cooper, K. L. Baughman, A. M. Feldman, A. Frustaci, M. Jessup, U. Kuhl, G. N. Levine, J. Narula, R. C. Starling, J. Towbin, et al.
The role of endomyocardial biopsy in the management of cardiovascular disease: A Scientific Statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology Endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology
Eur. Heart J.,
December 2, 2007;
28(24):
3076 - 3093.
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. T. Cooper, K. L. Baughman, A. M. Feldman, A. Frustaci, M. Jessup, U. Kuhl, G. N. Levine, J. Narula, R. C. Starling, J. Towbin, et al.
The Role of Endomyocardial Biopsy in the Management of Cardiovascular Disease: A Scientific Statement From the American Heart Association, the American College of Cardiology, and the European Society of Cardiology Endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology
J. Am. Coll. Cardiol.,
November 6, 2007;
50(19):
1914 - 1931.
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. T. Cooper, K. L. Baughman, A. M. Feldman, A. Frustaci, M. Jessup, U. Kuhl, G. N. Levine, J. Narula, R. C. Starling, J. Towbin, et al.
The Role of Endomyocardial Biopsy in the Management of Cardiovascular Disease: A Scientific Statement From the American Heart Association, the American College of Cardiology, and the European Society of Cardiology
Circulation,
November 6, 2007;
116(19):
2216 - 2233.
[Full Text]
[PDF]
|
|
|
|
|
|
|
Z. J. Wang, L. Lian, Q. Chen, H. Zhao, T. Asakura, and A. R. Cohen
1/T2 and Magnetic Susceptibility Measurements in a Gerbil Cardiac Iron Overload Model
Radiology,
March 1, 2005;
234(3):
749 - 755.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Goland, N. Beilinson, A. Kaftouri, S. Shimoni, A. Caspi, and S. D.H. Malnick
Hemochromatosis mutations are not linked to dilated cardiomyopathy in Israeli patients
Eur J Heart Fail,
August 1, 2004;
6(5):
547 - 550.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. M. Walker
The heart in thalassaemia
Eur. Heart J.,
January 2, 2002;
23(2):
102 - 105.
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Rajappan, N. G. Bellenger, L. Anderson, and D. J. Pennell
The role of cardiovascular magnetic resonance in heart failure
Eur J Heart Fail,
September 1, 2000;
2(3):
241 - 252.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W. J. Bartfay, F. Dawood, W. H. Wen, D. C. Lehotay, D. Hou, E. Bartfay, X. Luo, P. H. Backx, and P. P. Liu
Cardiac function and cytotoxic aldehyde production in a murine model of chronic iron-overload
Cardiovasc Res,
September 1, 1999;
43(4):
892 - 900.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. M. Gore and J. T. Fallon
Case 31-1994- A 25-Year-Old Man with the Recent Onset of Diabetes Mellitus and Congestive Heart Failure
N. Engl. J. Med.,
August 18, 1994;
331(7):
460 - 466.
[Full Text]
|
|
|
|
