Ventricular tachycardia and sudden death in myotonic dystrophy: clinical, electrophysiologic and pathologic features
LE Grigg,
W Chan,
HG Mond,
JK Vohra,
and
WF Downey
A 37 year old man who presented with a cardiomyopathy, conduction defects and atrial and ventricular arrhythmias was found to have the neuromuscular manifestations of myotonic dystrophy. Despite implantation of a permanent cardiac pacemaker, antiarrhythmic drug therapy and antiarrhythmic surgery, sudden death occurred. The results of electrophysiologic studies, coronary arteriography and pathologic findings are described. This case confirms previous observations that ventricular arrhythmias, in addition to atrial arrhythmias and conduction disturbances, are cardiac manifestations of myotonic dystrophy and can lead to sudden death.
This article has been cited by other articles:
|
|
|
|
 
W. J. Groh, M. R. Groh, C. Saha, J. C. Kincaid, Z. Simmons, E. Ciafaloni, R. Pourmand, R. F. Otten, D. Bhakta, G. V. Nair, et al.
Electrocardiographic Abnormalities and Sudden Death in Myotonic Dystrophy Type 1
N. Engl. J. Med.,
June 19, 2008;
358(25):
2688 - 2697.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G Pelargonio, A D. Russo, T Sanna, G De Martino, and F Bellocci
MYOTONIC DYSTROPHY AND THE HEART
Heart,
December 1, 2002;
88(6):
665 - 670.
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Lazarus, J. Varin, D. Babuty, F. Anselme, J. Coste, and D. Duboc
Long-term follow-up of arrhythmias in patients with myotonic dystrophy treated by pacing: A multicenter diagnostic pacemaker study
J. Am. Coll. Cardiol.,
November 6, 2002;
40(9):
1645 - 1652.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N R A Clarke, A D Kelion, J Nixon, D Hilton-Jones, and J C Forfar
Does cytosine-thymine-guanine (CTG) expansion size predict cardiac events and electrocardiographic progression in myotonic dystrophy?
Heart,
October 1, 2001;
86(4):
411 - 416.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Lazarus, J. Varin, Z. Ounnoughene, H. Radvanyi, C. Junien, J. Coste, P. Laforet, B. Eymard, H. M. Becane, S. Weber, et al.
Relationships Among Electrophysiological Findings and Clinical Status, Heart Function, and Extent of DNA Mutation in Myotonic Dystrophy
Circulation,
March 2, 1999;
99(8):
1041 - 1046.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
F A Bu'Lock, M Sood, J V De Giovanni, and S H Green
Left ventricular diastolic function in congenital myotonic dystrophy
Arch. Dis. Child.,
March 1, 1999;
80(3):
267 - 270.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
M.F. Phillips and P.S. Harper
Cardiac disease in myotonic dystrophy
Cardiovasc Res,
January 1, 1997;
33(1):
13 - 22.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. R. Milner, R. J. Hawley, M. Jachim, J. Lindsay Jr., and R. D. Fletcher
Ventricular Late Potentials in Myotonic Dystrophy
Ann Intern Med,
October 15, 1991;
115(8):
607 - 613.
[Abstract]
[PDF]
|
|
|
|
