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FOCUS ISSUE: VALVULAR HEART DISEASE: STATE-OF-THE-ART PAPER

Transcatheter Mitral and Pulmonary Valve Therapy

Nicolo Piazza, MD^_*, Anita Asgar, MD, Reda Ibrahim, MD and Raoul Bonan, MD^,_*

^_* Interventional Cardiology Department, Erasmus Medical Center, Thoraxcenter, Rotterdam, the Netherlands
Interventional Cardiology Department, Royal Brompton Hospital, London, United Kingdom
Interventional Cardiology Department, Montreal Heart Institute, Montreal, Quebec, Canada

Manuscript received June 12, 2008; revised manuscript received December 16, 2008, accepted December 23, 2008.

^_* Reprint requests and correspondence: Dr. Raoul Bonan, Institut de Cardiologie de Montreal, 5000 East Belanger, Montreal, H1T 1C8 Quebec, Canada (Email: raoul.bonan{at}mmic.net).

As the percentage of seniors continues to rise in many populations around the world, the already challenging burden of valvular heart disease will become even greater. Unfortunately, a significant proportion of patients with moderate-to-severe valve disease are refused or denied valve surgery based on age and/or accompanying comorbidities. Furthermore, because of advances in pediatric cardiology, the number of adult patients with congenital heart disease is on the rise and over time, these patients will likely require repeat high-risk surgical procedures. The aim of transcatheter valve therapies is to provide a minimally invasive treatment that is at least as effective as conventional valve surgery and is associated with less morbidity and mortality. The objective of this review was to provide an update on the clinical status, applicability, and limitations of transcatheter mitral and pulmonary valve therapies.

Key Words: transcatheter • mitral valve • pulmonary valve

Abbreviations and Acronyms   LV = left ventricle/ventricular   MI = myocardial infarction   MR = myocardial regurgitation   RVOT = right ventricular outflow tract   RV = right ventricle/ventricular

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J. Am. Coll. Cardiol. 2009 53: A28. [Full Text] [PDF]