Advertisement

Submit Manuscripts
Author Information
Subscribe/Renew
Order Reprints
Email Alerts
Feedback
RSS Feed
CME

About the Journal
Editorial Board & Staff

About JACC CME
Hardware/Software Requirements
Contact Us
Policy on Privacy and Confidentiality
Copyright Information

JACC Imaging Homepage JACC Interventions Homepage
Still not a subscriber to JACC Imaging or JACC Interventions?
Click here
to sign up now!

ACC.org
Cardiosmart
Cardiosource
CVN
Imaging Library
JACC Imaging
JACC Interventions

Click here for more guidelines.
2009 Focused Updates: ACC/AHA Guidelines for STEMI and ACC/AHA/SCAI Guidelines for PCI
2009 ACCF/AHA Focused Update on Perioperative Beta Blockade Incorporated Into the ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery
ACC 2009 Advocacy Position Statement: Principles for Comparative Effectiveness Research
CME Topic Collections Past Issues Search Current Issue Home
     

J Am Coll Cardiol, 2005; 45:954-959, doi:10.1016/j.jacc.2004.11.065
© 2005 by the American College of Cardiology Foundation
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (207)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Moreno, R.
Right arrow Articles by Macaya, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Moreno, R.
Right arrow Articles by Macaya, C.

EXPEDITED REVIEWS

Drug-eluting stent thrombosis

Results from a pooled analysis including 10 randomized studies

Raúl Moreno, MD, FESC*, Cristina Fernández, MD, Rosana Hernández, MD, FESC, Fernando Alfonso, MD, FESC, Dominick J. Angiolillo, MD, Manel Sabaté, MD, FESC, Javier Escaned, MD, FESC, Camino Bañuelos, MD, FESC, Antonio Fernández-Ortiz, MD, FESC and Carlos Macaya, MD, FESC

Division of Interventional Cardiology, Cardiovascular Institute, Hospital Clínico San Carlos, Madrid, Spain

Manuscript received September 2, 2004; revised manuscript received October 29, 2004, accepted November 2, 2004.

* Reprint requests and correspondence: Dr. Raúl Moreno, Division of Interventional Cardiology, Hospital Clinico San Carlos, Martín Lagos, s/n. 28040 Madrid, Spain (Email: raulmorenog{at}terra.es).

This work was presented in part at the 77th Annual Scientific Sessions of the American Heart Association, New Orleans, Louisiana, November 2004.

OBJECTIVES: We compared the risk of stent thrombosis (ST) after drug-eluting stents (DES) versus bare-metal stents (BMS), and tested the hypothesis that the risk of DES thrombosis is related to stent length.

BACKGROUND: Whether DES increase the risk of ST remains unclear. Given the very low restenosis rate after drug-eluting stenting, longer stents are frequently implanted for the same lesion length in comparison to BMS.

METHODS: We included in a meta-analysis 10 randomized studies comparing DES and BMS. Overall, 5,030 patients were included (2,602 were allocated to DES and 2,428 to BMS). The risk of thrombosis after DES versus BMS was compared, and the relationship between the rate of DES thrombosis and stent length was evaluated.

RESULTS: Incidence of ST was not increased in patients receiving DES (0.58% vs. 0.54% for BMS; odds ratio: 1.05; 95% confidence interval [CI]: 0.51 to 2.15; p = 1.000). The overall rate of ST did not differ significantly between patients receiving sirolimus- or paclitaxel-eluting stents (0.57% vs. 0.58%; p = 1.000). We found a significant relation between the rate of ST and the stented length (Y = –1.455 + 0.121 X; 95% CI for beta: 0.014 to 0.227; R = 0.716; p = 0.031). In patients with DES, mean stented length was longer in those suffering ST (23.4 ± 8.1 mm vs. 21.3 ± 4.1 mm, p = 0.025).

CONCLUSIONS: Drug-eluting stents do not increase the risk of ST, at least under appropriate anti-platelet therapy. The risk of ST after DES implantation is related to stent length.

Abbreviations and Acronyms
  BMS = bare-metal stents
  CI = confidence interval
  DES = drug-eluting stent
  LST = late stent thrombosis
  OR = odds ratio
  ST = stent thrombosis




This article has been cited by other articles:


Home page
 J Am Coll CardiolHome page
American College of Cardiology Foundation, American Heart Association Task Force on Practice, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interve, Society for Vascular Medicine, Society for Vascular Surgery, L. A. Fleisher, et al.
2009 ACCF/AHA Focused Update on Perioperative Beta Blockade Incorporated Into the ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery
J. Am. Coll. Cardiol., November 24, 2009; 54(22): e13 - e118.
[Full Text] [PDF]

Home page
 CirculationHome page
2007 WRITING COMMITTEE MEMBERS, L. A. Fleisher, J. A. Beckman, K. A. Brown, H. Calkins, E. L. Chaikof, K. E. Fleischmann, W. K. Freeman, J. B. Froehlich, E. K. Kasper, et al.
2009 ACCF/AHA Focused Update on Perioperative Beta Blockade Incorporated Into the ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Circulation, November 24, 2009; 120(21): e169 - e276.
[Full Text] [PDF]

Home page
 Eur Heart JHome page
T. Geisler, C. Zurn, R. Simonenko, M. Rapin, H. Kraibooj, A. Kilias, B. Bigalke, K. Stellos, M. Schwab, A. E. May, et al.
Early but not late stent thrombosis is influenced by residual platelet aggregation in patients undergoing coronary interventions
Eur. Heart J., October 6, 2009; (2009) ehp402v1.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
S. S. Brar, M. B. Leon, G. W. Stone, R. Mehran, J. W. Moses, S. K. Brar, and G. Dangas
Use of drug-eluting stents in acute myocardial infarction: a systematic review and meta-analysis.
J. Am. Coll. Cardiol., May 5, 2009; 53(18): 1677 - 1689.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol IntvHome page
H. Otake, J. Shite, J. Ako, T. Shinke, Y. Tanino, D. Ogasawara, T. Sawada, N. Miyoshi, H. Kato, B.-K. Koo, et al.
Local Determinants of Thrombus Formation Following Sirolimus-Eluting Stent Implantation Assessed by Optical Coherence Tomography
J. Am. Coll. Cardiol. Intv., May 1, 2009; 2(5): 459 - 466.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. Kaltoft, L. O. Jensen, M. Maeng, H. H. Tilsted, P. Thayssen, M. Bottcher, J. F. Lassen, L. R. Krusell, K. Rasmussen, K. N. Hansen, et al.
2-Year Clinical Outcomes After Implantation of Sirolimus-Eluting, Paclitaxel-Eluting, and Bare-Metal Coronary Stents Results From the WDHR (Western Denmark Heart Registry).
J. Am. Coll. Cardiol., February 24, 2009; 53(8): 658 - 664.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
J. Aoki, A. J. Lansky, R. Mehran, J. Moses, M. E. Bertrand, B. T. McLaurin, D. A. Cox, A. M. Lincoff, E. M. Ohman, H. D. White, et al.
Early Stent Thrombosis in Patients With Acute Coronary Syndromes Treated With Drug-Eluting and Bare Metal Stents: The Acute Catheterization and Urgent Intervention Triage Strategy Trial
Circulation, February 10, 2009; 119(5): 687 - 698.
[Abstract] [Full Text] [PDF]

Home page
 Ther Adv Cardiovasc DisHome page
B. E. Stahli, G. G. Camici, and F. C. Tanner
Drug-eluting stent thrombosis
Therapeutic Advances in Cardiovascular Disease, February 1, 2009; 3(1): 45 - 52.
[Abstract] [PDF]

Home page
 Eur Heart JHome page
F. Burzotta, A. Parma, C. Pristipino, A. Manzoli, F. Belloni, G. Sardella, S. Rigattieri, A. Danesi, P. Mazzarotto, F. Summaria, et al.
Angiographic and clinical outcome of invasively managed patients with thrombosed coronary bare metal or drug-eluting stents: the OPTIMIST study
Eur. Heart J., December 2, 2008; 29(24): 3011 - 3021.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc IntervHome page
A. K. Chhatriwalla and D. L. Bhatt
Should dual antiplatelet therapy after drug-eluting stents be continued for more than 1 year?: Dual Antiplatelet Therapy After Drug-Eluting Stents Should Be Continued for More Than One Year and Preferably Indefinitely
Circ Cardiovasc Interv, December 1, 2008; 1(3): 217 - 225.
[Full Text] [PDF]

Home page
 J Am Coll Cardiol IntvHome page
D.-W. Park, S.-C. Yun, S.-W. Lee, Y.-H. Kim, C. W. Lee, M.-K. Hong, S.-S. Cheong, J.-J. Kim, S.-W. Park, and S.-J. Park
Stent Thrombosis, Clinical Events, and Influence of Prolonged Clopidogrel Use After Placement of Drug-Eluting Stent: Data From an Observational Cohort Study of Drug-Eluting Versus Bare-Metal Stents
J. Am. Coll. Cardiol. Intv., October 1, 2008; 1(5): 494 - 503.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. H. Shishehbor, S. S. Goel, S. R. Kapadia, D. L. Bhatt, P. Kelly, R. E. Raymond, J. M. Galla, S. J. Brener, P. L. Whitlow, and S. G. Ellis
Long-Term Impact of Drug-Eluting Stents Versus Bare-Metal Stents on All-Cause Mortality
J. Am. Coll. Cardiol., September 23, 2008; 52(13): 1041 - 1048.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
A. J. Rastan, E. Boudriot, V. Falk, A. P. Kappetein, M. A. Borger, P. W. Serruys, G. Schuler, and F. W. Mohr
Frequency and pattern of de-novo three-vessel and left main coronary artery disease; insights from single center enrolment in the SYNTAX study
Eur. J. Cardiothorac. Surg., August 1, 2008; 34(2): 376 - 383.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
T. Chechi, S. Vecchio, G. Vittori, G. Giuliani, A. Lilli, G. Spaziani, L. Consoli, G. Baldereschi, G. G.L. Biondi-Zoccai, I. Sheiban, et al.
ST-segment elevation myocardial infarction due to early and late stent thrombosis a new group of high-risk patients.
J. Am. Coll. Cardiol., June 24, 2008; 51(25): 2396 - 2402.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol IntvHome page
J. Li, R. Jabara, L. Pendyala, Y. Otsuka, T. Shinke, D. Hou, K. Robinson, and N. Chronos
Abnormal Vasomotor Function of Porcine Coronary Arteries Distal to Sirolimus-Eluting Stents
J. Am. Coll. Cardiol. Intv., June 1, 2008; 1(3): 279 - 285.
[Abstract] [Full Text] [PDF]

Home page
 QJMHome page
P. Foley, S. Foley, T. Kinnaird, and R.A. Anderson
Clinical review: gastrointestinal bleeding after percutaneous coronary intervention: a deadly combination
QJM, June 1, 2008; 101(6): 425 - 433.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
A. Barilli, R. Visigalli, R. Sala, G. C. Gazzola, A. Parolari, E. Tremoli, S. Bonomini, A. Simon, E. I. Closs, V. Dall'Asta, et al.
In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function
Cardiovasc Res, June 1, 2008; 78(3): 563 - 571.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
P. Garg, D. J. Cohen, T. Gaziano, and L. Mauri
Balancing the Risks of Restenosis and Stent Thrombosis in Bare-Metal Versus Drug-Eluting Stents: Results of a Decision Analytic Model
J. Am. Coll. Cardiol., May 13, 2008; 51(19): 1844 - 1853.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
B X Chen, F Y Ma, W Luo, J H Ruan, W L Xie, X Z Zhao, S H Sun, X M Guo, F Wang, T Tian, et al.
Neointimal coverage of bare-metal and sirolimus-eluting stents evaluated with optical coherence tomography
Heart, May 1, 2008; 94(5): 566 - 570.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol IntvHome page
Y. Suzuki, F. Ikeno, T. Koizumi, F. Tio, A. C. Yeung, P. G. Yock, P. J. Fitzgerald, and W. F. Fearon
In Vivo Comparison Between Optical Coherence Tomography and Intravascular Ultrasound for Detecting Small Degrees of In-Stent Neointima After Stent Implantation
J. Am. Coll. Cardiol. Intv., April 1, 2008; 1(2): 168 - 173.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
G. Godet, Y. Le Manach, F. Lesache, S. Perbet, and P. Coriat
Drug-eluting stent thrombosis in patients undergoing non-cardiac surgery: is it always a problem?
Br. J. Anaesth., April 1, 2008; 100(4): 472 - 477.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. M. de la Torre-Hernandez, F. Alfonso, F. Hernandez, J. Elizaga, M. Sanmartin, E. Pinar, I. Lozano, J. M. Vazquez, J. Botas, A. Perez de Prado, et al.
Drug-eluting stent thrombosis: results from the multicenter Spanish registry ESTROFA (Estudio ESpanol sobre TROmbosis de stents FArmacoactivos).
J. Am. Coll. Cardiol., March 11, 2008; 51(10): 986 - 990.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
K. E. Kip, K. Hollabaugh, O. C. Marroquin, and D. O. Williams
The Problem With Composite End Points in Cardiovascular Studies The Story of Major Adverse Cardiac Events and Percutaneous Coronary Intervention.
J. Am. Coll. Cardiol., February 19, 2008; 51(7): 701 - 707.
[Abstract] [Full Text] [PDF]

Home page
 Card Surg AdultHome page
J. M. Wilson and J. T. Willerson
Myocardial Revascularization with Percutaneous Devices
Card. Surg. Adult, January 1, 2008; 3(2008): 573 - 598.
[Full Text]

Home page
 Eur Heart JHome page
E. Grube, K. D. Dawkins, G. Guagliumi, A. P. Banning, K. Zmudka, A. Colombo, L. Thuesen, K. Hauptman, J. Marco, W. Wijns, et al.
TAXUS VI 2-year follow-up: randomized comparison of polymer-based paclitaxel-eluting with bare metal stents for treatment of long, complex lesions
Eur. Heart J., November 1, 2007; 28(21): 2578 - 2582.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
L. A. Fleisher, J. A. Beckman, K. A. Brown, H. Calkins, E. L. Chaikof, K. E. Fleischmann, W. K. Freeman, J. B. Froehlich, E. K. Kasper, J. R. Kersten, et al.
ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery) Developed in Collaboration With the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery
J. Am. Coll. Cardiol., October 23, 2007; 50(17): e159 - e242.
[Full Text] [PDF]

Home page
 CirculationHome page
S. Windecker and B. Meier
Late Coronary Stent Thrombosis
Circulation, October 23, 2007; 116(17): 1952 - 1965.
[Full Text] [PDF]

Home page
 CirculationHome page
L. A. Fleisher, J. A. Beckman, K. A. Brown, H. Calkins, E. L. Chaikof, K. E. Fleischmann, W. K. Freeman, J. B. Froehlich, E. K. Kasper, J. R. Kersten, et al.
ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery)
Circulation, October 23, 2007; 116(17): e418 - e500.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. Schomig, A. Dibra, S. Windecker, J. Mehilli, J. Suarez de Lezo, C. Kaiser, S.-J. Park, J.-J. Goy, J.-H. Lee, E. Di Lorenzo, et al.
A Meta-Analysis of 16 Randomized Trials of Sirolimus-Eluting Stents Versus Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease
J. Am. Coll. Cardiol., October 2, 2007; 50(14): 1373 - 1380.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
G. Sianos, M. I. Papafaklis, J. Daemen, S. Vaina, C. A. van Mieghem, R. T. van Domburg, L. K. Michalis, and P. W. Serruys
Angiographic Stent Thrombosis After Routine Use of Drug-Eluting Stents in ST-Segment Elevation Myocardial Infarction: The Importance of Thrombus Burden
J. Am. Coll. Cardiol., August 14, 2007; 50(7): 573 - 583.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
F. Airoldi, A. Colombo, N. Morici, A. Latib, J. Cosgrave, L. Buellesfeld, E. Bonizzoni, M. Carlino, U. Gerckens, C. Godino, et al.
Incidence and Predictors of Drug-Eluting Stent Thrombosis During and After Discontinuation of Thienopyridine Treatment
Circulation, August 14, 2007; 116(7): 745 - 754.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. Machecourt, N. Danchin, J. M. Lablanche, J. M. Fauvel, J. L. Bonnet, S. Marliere, A. Foote, J. L. Quesada, H. Eltchaninoff, G. Vanzetto, et al.
Risk Factors for Stent Thrombosis After Implantation of Sirolimus-Eluting Stents in Diabetic and Nondiabetic Patients: The EVASTENT Matched-Cohort Registry
J. Am. Coll. Cardiol., August 7, 2007; 50(6): 501 - 508.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
M. R Bennett
Vascular pathology as a result of drug-eluting stents
Heart, August 1, 2007; 93(8): 895 - 896.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
L. O. Jensen, M. Maeng, A. Kaltoft, P. Thayssen, H. H. T. Hansen, M. Bottcher, J. F. Lassen, L. R. Krussel, K. Rasmussen, K. N. Hansen, et al.
Stent Thrombosis, Myocardial Infarction, and Death After Drug-Eluting and Bare-Metal Stent Coronary Interventions
J. Am. Coll. Cardiol., July 31, 2007; 50(5): 463 - 470.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. Jaffe and B. H. Strauss
Late and Very Late Thrombosis of Drug-Eluting Stents: Evolving Concepts and Perspectives
J. Am. Coll. Cardiol., July 10, 2007; 50(2): 119 - 127.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
D. R. Holmes Jr, D. J. Kereiakes, W. K. Laskey, A. Colombo, S. G. Ellis, T. D. Henry, J. J. Popma, P. W.J.C. Serruys, T. Kimura, D. O. Williams, et al.
Thrombosis and Drug-Eluting Stents: An Objective Appraisal
J. Am. Coll. Cardiol., July 10, 2007; 50(2): 109 - 118.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
R. Moreno, C. Fernandez, A. Sanchez-Recalde, G. Galeote, L. Calvo, F. Alfonso, R. Hernandez, R. Sanchez-Aquino, D. J. Angiolillo, S. Villarreal, et al.
Clinical impact of in-stent late loss after drug-eluting coronary stent implantation
Eur. Heart J., July 1, 2007; 28(13): 1583 - 1591.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
P. Buonamici, R. Marcucci, A. Migliorini, G. F. Gensini, A. Santini, R. Paniccia, G. Moschi, A. M. Gori, R. Abbate, and D. Antoniucci
Impact of Platelet Reactivity After Clopidogrel Administration on Drug-Eluting Stent Thrombosis
J. Am. Coll. Cardiol., June 19, 2007; 49(24): 2312 - 2317.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
G. W. Stone, S. G. Ellis, A. Colombo, K. D. Dawkins, E. Grube, D. E. Cutlip, M. Friedman, D. S. Baim, and J. Koglin
Offsetting Impact of Thrombosis and Restenosis on the Occurrence of Death and Myocardial Infarction After Paclitaxel-Eluting and Bare Metal Stent Implantation
Circulation, June 5, 2007; 115(22): 2842 - 2847.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
E. Camenzind, P. G. Steg, and W. Wijns
A Cause for Concern
Circulation, March 20, 2007; 115(11): 1440 - 1455.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
S. G. Ellis, A. Colombo, E. Grube, J. Popma, J. Koglin, K. D. Dawkins, and G. W. Stone
Incidence, Timing, and Correlates of Stent Thrombosis With the Polymeric Paclitaxel Drug-Eluting Stent: A TAXUS II, IV, V, and VI Meta-Analysis of 3,445 Patients Followed for Up to 3 Years
J. Am. Coll. Cardiol., March 13, 2007; 49(10): 1043 - 1051.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
A. Kastrati, J. Mehilli, J. Pache, C. Kaiser, M. Valgimigli, H. Kelbaek, M. Menichelli, M. Sabate, M. J. Suttorp, D. Baumgart, et al.
Analysis of 14 Trials Comparing Sirolimus-Eluting Stents with Bare-Metal Stents
N. Engl. J. Med., March 8, 2007; 356(10): 1030 - 1039.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
L. Mauri, W.-h. Hsieh, J. M. Massaro, K. K.L. Ho, R. D'Agostino, and D. E. Cutlip
Stent Thrombosis in Randomized Clinical Trials of Drug-Eluting Stents
N. Engl. J. Med., March 8, 2007; 356(10): 1020 - 1029.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
H.-P. B.-L. Rocca, C. Kaiser, M. Pfisterer, and on behalf of the BASKET Investigators
Targeted stent use in clinical practice based on evidence from the BAsel Stent Cost Effectiveness Trial (BASKET)
Eur. Heart J., March 2, 2007; 28(6): 719 - 725.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
T. F. Luscher, J. Steffel, F. R. Eberli, M. Joner, G. Nakazawa, F. C. Tanner, and R. Virmani
Drug-Eluting Stent and Coronary Thrombosis: Biological Mechanisms and Clinical Implications
Circulation, February 27, 2007; 115(8): 1051 - 1058.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. Colombo and S. J. Corbett
Reply
J. Am. Coll. Cardiol., February 6, 2007; 49(5): 627 - 627.
[Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
N. N. Lang and D. E. Newby
Emerging Thrombotic Effects of Drug Eluting Stents
Arterioscler Thromb Vasc Biol, February 1, 2007; 27(2): 261 - 262.
[Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
J. A.S. Muldowney III, J. R. Stringham, S. E. Levy, L. A. Gleaves, M. Eren, R. N. Piana, and D. E. Vaughan
Antiproliferative Agents Alter Vascular Plasminogen Activator Inhibitor-1 Expression: A Potential Prothrombotic Mechanism of Drug-Eluting Stents
Arterioscler Thromb Vasc Biol, February 1, 2007; 27(2): 400 - 406.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
E. C. Keeley and L. D. Hillis
Primary PCI for Myocardial Infarction with ST-Segment Elevation
N. Engl. J. Med., January 4, 2007; 356(1): 47 - 54.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. Pfisterer, H. P. Brunner-La Rocca, P. T. Buser, P. Rickenbacher, P. Hunziker, C. Mueller, R. Jeger, F. Bader, S. Osswald, C. Kaiser, et al.
Late Clinical Events After Clopidogrel Discontinuation May Limit the Benefit of Drug-Eluting Stents: An Observational Study of Drug-Eluting Versus Bare-Metal Stents
J. Am. Coll. Cardiol., December 19, 2006; 48(12): 2584 - 2591.
[Abstract] [Full Text] [PDF]

Home page
 Am J Health Syst PharmHome page
R. K. McAllister, G. J. Dehmer, and T. A. Meyer
Premature discontinuation of antiplatelet therapy in patients with drug-eluting coronary stents
Am. J. Health Syst. Pharm., December 1, 2006; 63(23): 2308 - 2310.
[Full Text] [PDF]

Home page
 Eur Heart JHome page
D. R. Holmes Jr, J. W. Moses, J. Schofer, M.-C. Morice, E. Schampaert, and M. B. Leon
Cause of death with bare metal and sirolimus-eluting stents
Eur. Heart J., December 1, 2006; 27(23): 2815 - 2822.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
F. Saia, G. Piovaccari, A. Manari, A. Santarelli, A. Benassi, E. Aurier, P. Sangiorgio, F. Tarantino, G. Geraci, G. Vecchi, et al.
Clinical Outcomes for Sirolimus-Eluting Stents and Polymer-Coated Paclitaxel-Eluting Stents in Daily Practice: Results From a Large Multicenter Registry
J. Am. Coll. Cardiol., October 3, 2006; 48(7): 1312 - 1318.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
W. Desmet
Delayed neointimal healing after drug-eluting stent implantation: seeing is believing
Eur. Heart J., September 2, 2006; 27(18): 2147 - 2149.
[Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
H. B. Barner
Status of percutaneous coronary intervention and coronary artery bypass.
Eur. J. Cardiothorac. Surg., September 1, 2006; 30(3): 419 - 424.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
D. J. Kereiakes, H. Wang, J. J. Popma, R. E. Kuntz, D. J. Donohoe, J. Schofer, E. Schampaert, B. Meier, M. B. Leon, and J. W. Moses
Periprocedural and Late Consequences of Overlapping Cypher Sirolimus-Eluting Stents: Pooled Analysis of Five Clinical Trials
J. Am. Coll. Cardiol., July 4, 2006; 48(1): 21 - 31.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. Colombo and S. J. Corbett
Drug-Eluting Stent Thrombosis: Increasingly Recognized But Too Frequently Overemphasized
J. Am. Coll. Cardiol., July 4, 2006; 48(1): 203 - 205.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. Joner, A. V. Finn, A. Farb, E. K. Mont, F. D. Kolodgie, E. Ladich, R. Kutys, K. Skorija, H. K. Gold, and R. Virmani
Pathology of Drug-Eluting Stents in Humans: Delayed Healing and Late Thrombotic Risk
J. Am. Coll. Cardiol., July 4, 2006; 48(1): 193 - 202.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
J. A. Spertus, R. Kettelkamp, C. Vance, C. Decker, P. G. Jones, J. S. Rumsfeld, J. C. Messenger, S. Khanal, E. D. Peterson, R. G. Bach, et al.
Prevalence, Predictors, and Outcomes of Premature Discontinuation of Thienopyridine Therapy After Drug-Eluting Stent Placement: Results From the PREMIER Registry
Circulation, June 20, 2006; 113(24): 2803 - 2809.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
S. Tsimikas
Drug-Eluting Stents and Late Adverse Clinical Outcomes: Lessons Learned, Lessons Awaited
J. Am. Coll. Cardiol., May 16, 2006; 47(10): 2112 - 2115.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
S. R. Dixon, C. L. Grines, and W. W. O'Neill
The Year in Interventional Cardiology
J. Am. Coll. Cardiol., April 18, 2006; 47(8): 1689 - 1706.
[Full Text] [PDF]

Home page
 CirculationHome page
P. Urban, A. H. Gershlick, G. Guagliumi, P. Guyon, C. Lotan, J. Schofer, A. Seth, J. E. Sousa, W. Wijns, C. Berge, et al.
Safety of Coronary Sirolimus-Eluting Stents in Daily Clinical Practice: One-Year Follow-Up of the e-Cypher Registry
Circulation, March 21, 2006; 113(11): 1434 - 1441.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. G. Raja
Drug-Eluting Stents and the Future of Coronary Artery Bypass Surgery: Facts and Fiction
Ann. Thorac. Surg., March 1, 2006; 81(3): 1162 - 1171.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
F. Alfonso
Residual coronary dissections after drug-eluting stenting: the good, the bad, and the ugly
Eur. Heart J., March 1, 2006; 27(5): 503 - 505.
[Full Text] [PDF]

Home page
 HeartHome page
R. Seabra-Gomes
Percutaneous coronary interventions with drug eluting stents for diabetic patients.
Heart, March 1, 2006; 92(3): 410 - 419.
[Full Text] [PDF]

Home page
 CirculationHome page
P. K. Kuchulakanti, W. W. Chu, R. Torguson, P. Ohlmann, S.-W. Rha, L. C. Clavijo, S.-W. Kim, A. Bui, N. Gevorkian, Z. Xue, et al.
Correlates and Long-Term Outcomes of Angiographically Proven Stent Thrombosis With Sirolimus- and Paclitaxel-Eluting Stents
Circulation, February 28, 2006; 113(8): 1108 - 1113.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
H. Kelbaek, L. Thuesen, S. Helqvist, L. Klovgaard, E. Jorgensen, S. Aljabbari, K. Saunamaki, L. R. Krusell, G. V.H. Jensen, H. E. Botker, et al.
The Stenting Coronary Arteries in Non-stress/benestent Disease (SCANDSTENT) Trial
J. Am. Coll. Cardiol., January 17, 2006; 47(2): 449 - 455.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. N. DeMaria, O. Ben-Yehuda, D. Berman, G. K. Feld, G. S. Ginsburg, B. H. Greenberg, W. Y.W. Lew, D. Sahn, and S. Tsimikas
Highlights of the Year in JACC 2005
J. Am. Coll. Cardiol., January 3, 2006; 47(1): 184 - 202.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
H. Kaneda
Drug-Eluting Stent Thrombosis: A Pooled Analysis
J. Am. Coll. Cardiol., January 3, 2006; 47(1): 214 - 214.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. Moreno, C. Fernandez, and C. Macaya
Drug-eluting stent thrombosis: Results from a pooled analysis including 10 randomized studies: Reply
J. Am. Coll. Cardiol., January 3, 2006; 47(1): 214 - 215.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
H. Kaneda
Drug-Eluting Stent Thrombosis: A Pooled Analysis
J. Am. Coll. Cardiol., December 13, 2005; (2005) j.jacc.2005.10.014v1.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. Moreno, C. Fernandez, and C. Macaya
Drug-eluting stent thrombosis: Results from a pooled analysis including 10 randomized studies.REPLY
J. Am. Coll. Cardiol., December 13, 2005; (2005) j.jacc.2005.10.015v1.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
H. Kelbaek, L. Thuesen, S. Helqvist, L. Klovgaard, E. Jorgensen, S. Aljabbari, K. Saunamaki, L. R. Krusell, G. V.H. Jensen, H. E. Botker, et al.
The Stenting Coronary Arteries in Non-stress/benestent Disease (SCANDSTENT) Trial
J. Am. Coll. Cardiol., December 13, 2005; (2005) j.jacc.2005.10.045v1.
[Abstract] [Full Text] [PDF]


 
  CME Topic Collections Past Issues Search Current Issue Home

Advertisement