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CLINICAL RESEARCH: MINI-FOCUS: TRANSCATHETER CLOSURE OF ASD AND PFO

Long-term outcome of transcatheter secundum-type atrial septal defect closure using Amplatzer septal occluders

Jozef Masura, MD, PhD, Pavol Gavora, MD and Toma Podnar, MD, PhD^*

Children's Cardiac Center, University Children's Hospital, Bratislava, Slovakia

Manuscript received June 3, 2004; revised manuscript received September 13, 2004, accepted October 25, 2004.

^* Reprint requests and correspondence: Dr. Toma Podnar, University Children's Hospital, University Medical Center, Vrazov trg 1, 1525 Ljubljana, Slovenia (Email: tomaz.podnar{at}mf.uni-lj.si).

OBJECTIVES: The aim of this study was to assess long-term results of percutaneous closure of secundum-type atrial septal defect (ASD II) using Amplatzer septal occluders (ASO).

BACKGROUND: Only immediate-, short-, and intermediate-term results of ASO implantation are known so far.

METHODS: Between September 1995 and January 2000, 151 patients underwent a successful percutaneous closure of ASD II in our institution. All were included in the present study and were followed up until September 2004.

RESULTS: This group of patients was followed up from 56 to 108 months (median 78 months). The mean stretched defect diameter was 15.9 ± 4.8 mm. There were no deaths or significant complications during the study. At three years of follow-up, all defects were completely closed and remained closed thereafter.

CONCLUSIONS: Since the first human implantations in September 1995, the Amplatzer septal occluder proved as a safe and effective device for percutaneous closure of ASD II.

Abbreviations and Acronyms   ASD II = secundum-type atrial septal defect   ASO = Amplatzer septal occluder   TEE = transesophageal echocardiography   TTE = transthoracic echocardiography

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