|
|
||||||||||
|
J Am Coll Cardiol, 2004; 44:2157-2165, doi:10.1016/j.jacc.2004.08.065 © 2004 by the American College of Cardiology Foundation |
Hôpital Cardiologique du Haut Leveque, Pessac, France
Manuscript received March 26, 2004; accepted August 23, 2004.
* Reprint requests and correspondence: Dr. Stephane Garrigue, Hôpital Cardiologique du Haut Lévèque, 19 Avenue de Magellan, Pessac Cedex 33604, France (Email: stephane.garrigue{at}chu-bordeaux.fr).
OBJECTIVES: We sought to evaluate the relationship between hemodynamic and ventricular dyssynchrony parameters in patients undergoing simultaneous and sequential biventricular pacing (BVP).
BACKGROUND: Various echocardiographic parameters of ventricular dyssynchrony have been proposed to screen and optimize BVP therapy.
METHODS: Forty-one patients with heart failure undergoing BVP implantation were studied. Echocardiography coupled with tissue tracking and pulsed Doppler tissue imaging (DTI) was performed before and after BVP implantation and after three months of optimized BVP. Indexes of inter- or intraventricular dyssynchrony were correlated with hemodynamic changes during simultaneous and sequential BVP (10 intervals of right ventricular [RV] or left ventricular [LV] pre-excitation).
RESULTS: Variations in intra-LV delaypeak, intra-LV delayonset, and index of LV dyssynchrony measured by pulsed DTI were highly correlated with those of cardiac output (r = 0.67, r = 0.64, and r = 0.67, respectively; p < 0.001) and mitral regurgitation (r = 0.68, r = 0.63, and r = 0.68, respectively; p < 0.001), whereas variations in the extent of myocardium displaying delayed longitudinal contraction (r = 0.48 and r = 0.51, respectively; p < 0.05) and the variations in septal-to-posterior wall motion delay (r = 0.41, p < 0.05 and r = 0.24, p = NS, respectively) were less correlated. The changes in interventricular dyssynchrony were not significantly correlated (p = NS). Compared with simultaneous BVP, individually optimized sequential BVP significantly increased cardiac output (p < 0.01), decreased mitral regurgitation (p < 0.05), and improved all parameters of intra-LV dyssynchrony (p < 0.01). At three months, a significant reverse mechanical LV remodeling was observed with significantly decreased LV volumes (p < 0.01) associated with an increased LV ejection fraction (p = 0.035).
CONCLUSIONS: Specific echocardiographic measurements of ventricular dyssynchrony are highly correlated with hemodynamic changes and may be a useful adjunct in the selection and optimization of BVP. Individually optimized sequential BVP provided a significant early hemodynamic improvement compared with simultaneous BVP.
| ||||||||||||
This article has been cited by other articles:
![]() |
T. Stanton, N. M. Hawkins, K. J. Hogg, N. E.R. Goodfield, M. C. Petrie, and J. J.V. McMurray How should we optimize cardiac resynchronization therapy? Eur. Heart J., August 28, 2008; (2008) ehn380v1. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. H. Lim, G. Y.H. Lip, and J. E. Sanderson Ventricular optimization of biventricular pacing: a systematic review Europace, August 1, 2008; 10(8): 901 - 906. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. J. Anderson, C. Miyazaki, G. R. Sutherland, and J. K. Oh Patient Selection and Echocardiographic Assessment of Dyssynchrony in Cardiac Resynchronization Therapy Circulation, April 15, 2008; 117(15): 2009 - 2023. [Full Text] [PDF] |
||||
![]() |
M. Brignole, D. Oddone, R. Maggi, G. Lupi, R. Bollini, S. Corallo, S. Robotti, A. Solano, P. Donateo, and F. Croci Resynchronization of the left ventricular contraction by tailored programming of right and left ventricular pacing Europace, April 1, 2008; 10(4): 489 - 495. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Bordachar, L. Labrousse, J.-B. Thambo, P. Reant, S. Lafitte, M. D. O'Neill, P. Jais, M. Haissaguerre, J. Clementy, and P. Dos Santos Haemodynamic impact of the left ventricular pacing site during graded ischaemia in an open-chest pig model Europace, February 1, 2008; 10(2): 242 - 248. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Stockburger, S. Fateh-Moghadam, A. Nitardy, O. Celebi, A. Krebs, D. Habedank, and R. Dietz Baseline Doppler parameters are useful predictors of chronic left ventricular reduction in size by cardiac resynchronization therapy Europace, January 1, 2008; 10(1): 69 - 74. [Abstract] [Full Text] [PDF] |
||||
![]() |
R E Lane, A W C Chow, J Mayet, D P Francis, N S Peters, R J Schilling, and D W Davies The interaction of interventricular pacing intervals and left ventricular lead position during temporary biventricular pacing evaluated by tissue Doppler imaging Heart, November 1, 2007; 93(11): 1426 - 1432. [Abstract] [Full Text] [PDF] |
||||
![]() |
Authors/Task Force Members, P. E. Vardas, A. Auricchio, J.-J. Blanc, J.-C. Daubert, H. Drexler, H. Ector, M. Gasparini, C. Linde, F. B. Morgado, et al. Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in Collaboration with the European Heart Rhythm Association Europace, October 1, 2007; 9(10): 959 - 998. [Full Text] [PDF] |
||||
![]() |
Authors/Task Force Members, P. E. Vardas, A. Auricchio, J.-J. Blanc, J.-C. Daubert, H. Drexler, H. Ector, M. Gasparini, C. Linde, F. B. Morgado, et al. Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in Collaboration with the European Heart Rhythm Association Eur. Heart J., September 2, 2007; 28(18): 2256 - 2295. [Full Text] [PDF] |
||||
![]() |
P. Lim, C. Bars, L. Mitchell-Heggs, C. Roiron, N. Elbaz, B. Hamdaoui, N. Lellouche, J.-L. Dubois-Rande, and P. Gueret Importance of contractile reserve for CRT Europace, September 1, 2007; 9(9): 739 - 743. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Arita, G. P. Sorescu, B. T. Schuler, L. S. Schmarkey, J. D. Merlino, J. Vinten-Johansen, A. R. Leon, R. P. Martin, and D. Sorescu Speckle-tracking strain echocardiography for detecting cardiac dyssynchrony in a canine model of dyssynchrony and heart failure Am J Physiol Heart Circ Physiol, July 1, 2007; 293(1): H735 - H742. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. A. McAlister, J. Ezekowitz, N. Hooton, B. Vandermeer, C. Spooner, D. M. Dryden, R. L. Page, M. A. Hlatky, and B. H. Rowe Cardiac Resynchronization Therapy for Patients With Left Ventricular Systolic Dysfunction: A Systematic Review JAMA, June 13, 2007; 297(22): 2502 - 2514. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Schmidt, J. Frielingsdorf, M. Debrunner, R. Tavakoli, M. Genoni, E. Straumann, O. Bertel, and B. Naegeli Acute biventricular pacing after cardiac surgery has no influence on regional and global left ventricular systolic function Europace, June 1, 2007; 9(6): 432 - 436. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. D. Burkhardt and B. L. Wilkoff Interventional Electrophysiology and Cardiac Resynchronization Therapy: Delivering Electrical Therapies for Heart Failure Circulation, April 24, 2007; 115(16): 2208 - 2220. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. H. Schoenfeld Contemporary Pacemaker and Defibrillator Device Therapy: Challenges Confronting the General Cardiologist Circulation, February 6, 2007; 115(5): 638 - 653. [Full Text] [PDF] |
||||
![]() |
O. I.I. Soliman, D. A.M.J. Theuns, M. L. Geleijnse, A. M. Anwar, A. Nemes, K. Caliskan, W. B. Vletter, L. J. Jordaens, and F. J. T. Cate Spectral pulsed-wave tissue Doppler imaging lateral-to-septal delay fails to predict clinical or echocardiographic outcome after cardiac resynchronization therapy Europace, February 1, 2007; 9(2): 113 - 118. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. P. Badano, O. Gaddi, C. Peraldo, G. Lupi, M. Sitges, F. Parthenakis, S. Molteni, M. R. Pagliuca, B. Sassone, P. Di Stefano, et al. Left ventricular electromechanical delay in patients with heart failure and normal QRS duration and in patients with right and left bundle branch block Europace, January 1, 2007; 9(1): 41 - 47. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. B. Bleeker, E. R. Holman, P. Steendijk, E. Boersma, E. E. van der Wall, M. J. Schalij, and J. J. Bax Cardiac Resynchronization Therapy in Patients With a Narrow QRS Complex J. Am. Coll. Cardiol., December 5, 2006; 48(11): 2243 - 2250. [Abstract] [Full Text] [PDF] |
||||
![]() |
Z I Whinnett, J E R Davies, K Willson, C H Manisty, A W Chow, R A Foale, D Wyn Davies, A D Hughes, J Mayet, and D P Francis Haemodynamic effects of changes in atrioventricular and interventricular delay in cardiac resynchronisation therapy show a consistent pattern: analysis of shape, magnitude and relative importance of atrioventricular and interventricular delay Heart, November 1, 2006; 92(11): 1628 - 1634. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. A. Quinn, G. Berberian, S. E. Cabreriza, L. J. Maskin, A. D. Weinberg, J. W. Holmes, and H. M. Spotnitz Effects of sequential biventricular pacing during acute right ventricular pressure overload Am J Physiol Heart Circ Physiol, November 1, 2006; 291(5): H2380 - H2387. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Lafitte, P. Bordachar, M. Lafitte, S. Garrigue, S. Reuter, P. Reant, K. Serri, V. Lebouffos, M. Berrhouet, P. Jais, et al. Dynamic Ventricular Dyssynchrony: An Exercise-Echocardiography Study J. Am. Coll. Cardiol., June 6, 2006; 47(11): 2253 - 2259. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Donal, C. Leclercq, C. Linde, and J.-C. Daubert Effects of cardiac resynchronization therapy on disease progression in chronic heart failure Eur. Heart J., May 1, 2006; 27(9): 1018 - 1025. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Steendijk, S. A. Tulner, J. J. Bax, P. V. Oemrawsingh, G. B. Bleeker, L. van Erven, H. Putter, H. F. Verwey, E. E. van der Wall, and M. J. Schalij Hemodynamic Effects of Long-Term Cardiac Resynchronization Therapy: Analysis by Pressure-Volume Loops Circulation, March 14, 2006; 113(10): 1295 - 1304. [Abstract] [Full Text] [PDF] |
||||
![]() |
X. A. A. M. Verbeek, A. Auricchio, Y. Yu, J. Ding, T. Pochet, K. Vernooy, A. Kramer, J. Spinelli, and F. W. Prinzen Tailoring cardiac resynchronization therapy using interventricular asynchrony. Validation of a simple model Am J Physiol Heart Circ Physiol, March 1, 2006; 290(3): H968 - H977. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. E. Weyman The Year in Echocardiography J. Am. Coll. Cardiol., February 21, 2006; 47(4): 856 - 863. [Full Text] [PDF] |
||||
![]() |
J. J. Bax, T. Abraham, S. S. Barold, O. A. Breithardt, J. W.H. Fung, S. Garrigue, J. Gorcsan III, D. L. Hayes, D. A. Kass, J. Knuuti, et al. Cardiac Resynchronization Therapy: Part 1--Issues Before Device Implantation J. Am. Coll. Cardiol., December 20, 2005; 46(12): 2153 - 2167. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. M. Aranda Jr, G. W. Woo, R. S. Schofield, E. M. Handberg, J. A. Hill, A. B. Curtis, S. F. Sears, J. S. Goff, D. F. Pauly, and J. B. Conti Management of Heart Failure After Cardiac Resynchronization Therapy: Integrating Advanced Heart Failure Treatment With Optimal Device Function J. Am. Coll. Cardiol., December 20, 2005; 46(12): 2193 - 2198. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. N. DeMaria, O. Ben-Yehuda, D. Berman, G. K. Feld, B. H. Greenberg, J. D. Knoke, K. U. Knowlton, W. Y.W. Lew, J. Narula, D. Sahn, et al. Highlights of the year in JACC 2004 J. Am. Coll. Cardiol., January 4, 2005; 45(1): 137 - 153. [Full Text] [PDF] |
||||
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |