|
|
||||||||||
|
J Am Coll Cardiol, 2004; 44:2149-2156, doi:10.1016/j.jacc.2004.08.064 © 2004 by the American College of Cardiology Foundation |






* Southern Arizona VA Health Care System and the University of Arizona Sarver Heart Center, Tucson, Arizona
VA Cooperative Studies Program Coordinating Center, Hines, Illinois
Manuscript received May 6, 2004; revised manuscript received August 16, 2004, accepted August 25, 2004.
* Reprint requests and correspondence: Dr. Steven Goldman, Cardiology Section (1-111C), Southern Arizona VA Health Care System, 3601 South 6th Avenue, Tucson, Arizona 85723 (Email: steven.goldman{at}med.va.gov).
OBJECTIVES: This study defined long-term patency of saphenous vein grafts (SVG) and internal mammary artery (IMA) grafts.
BACKGROUND: This VA Cooperative Studies Trial defined 10-year SVG patency in 1,074 patients and left IMA patency in 457 patients undergoing coronary artery bypass grafting (CABG).
METHODS: Patients underwent cardiac catheterizations at 1 week and 1, 3, 6, and 10 years after CABG.
RESULTS: Patency at 10 years was 61% for SVGs compared with 85% for IMA grafts (p < 0.001). If a SVG or IMA graft was patent at 1 week, that graft had a 68% and 88% chance, respectively, of being patent at 10 years. The SVG patency to the left anterior descending artery (LAD) (69%) was better (p < 0.001) than to the right coronary artery (56%), or circumflex (58%). Recipient vessel size was a significant predictor of graft patency, in vessels >2.0 mm in diameter SVG patency was 88% versus 55% in vessels
2.0 mm (p < 0.001). Other positive significant predictors of graft patency were use of aspirin after bypass, older age, lower serum cholesterol, and lowest Canadian Functional Class (p < 0.001 to 0.058).
CONCLUSIONS: The 10-year patency of IMA grafts is better than SVGs. The 10-year patency for SVGs is better and the 10-year patency for IMA grafts is worse than expected. The 10-year patency of SVGs to the LAD is better than that to the right or circumflex. The best long-term predictors of SVG graft patency are grafting into the LAD and grafting into a vessel that is >2.0 mm in diameter.
| ||||||||
This article has been cited by other articles:
![]() |
J. Kempfert, U. T. Opfermann, M. Richter, T. Bossert, F. W. Mohr, and J. F. Gummert Twelve-month patency with the PAS-port proximal connector device: a single center prospective randomized trial. Ann. Thorac. Surg., May 1, 2008; 85(5): 1579 - 1584. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. V. Ozcan, H. Evrengul, I. Goksin, S. Gur, and A. Kaftan 30-Year Patency of a Saphenous Vein Graft in Coronary Bypass Graft Surgery Ann. Thorac. Surg., April 1, 2008; 85(4): e23 - e23. [Full Text] [PDF] |
||||
![]() |
N. S. Burris, E. N. Brown, M. Grant, Z. N. Kon, M. Gibber, J. Gu, K. Schwartz, S. Kallam, A. Joshi, R. Vitali, et al. Optical Coherence Tomography Imaging as a Quality Assurance Tool for Evaluating Endoscopic Harvest of the Radial Artery Ann. Thorac. Surg., April 1, 2008; 85(4): 1271 - 1277. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. B. Barner Operative Treatment of Coronary Atherosclerosis Ann. Thorac. Surg., April 1, 2008; 85(4): 1473 - 1482. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. J. Magee, J. H. Alexander, G. Hafley, T. B. Ferguson Jr, C. M. Gibson, R. A. Harrington, E. D. Peterson, R. M. Califf, N. T. Kouchoukos, M. A. Herbert, et al. Coronary Artery Bypass Graft Failure After On-Pump and Off-Pump Coronary Artery Bypass: Findings From PREVENT IV Ann. Thorac. Surg., February 1, 2008; 85(2): 494 - 500. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. A.R. Hayward and B. F. Buxton Contemporary Coronary Graft Patency: 5-Year Observational Data From a Randomized Trial of Conduits Ann. Thorac. Surg., September 1, 2007; 84(3): 795 - 799. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. J. Murphy, A. C. Newby, J. Y. Jeremy, A. Baumbach, and G. D. Angelini A randomized trial of an external Dacron sheath for the prevention of vein graft disease: The Extent study J. Thorac. Cardiovasc. Surg., August 1, 2007; 134(2): 504 - 505. [Full Text] [PDF] |
||||
![]() |
E. J.W. Wallitt, M. Jevon, and P. I. Hornick Therapeutics of Vein Graft Intimal Hyperplasia: 100 Years On Ann. Thorac. Surg., July 1, 2007; 84(1): 317 - 323. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. J. Botman, J. Schonberger, S. Koolen, O. Penn, H. Botman, N. Dib, E. Eeckhout, and N. Pijls Does Stenosis Severity of Native Vessels Influence Bypass Graft Patency? A Prospective Fractional Flow Reserve-Guided Study Ann. Thorac. Surg., June 1, 2007; 83(6): 2093 - 2097. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Renda, R. Di Pillo, A. D'Alleva, A. Sciartilli, M. Zimarino, E. De Candia, R. Landolfi, G. Di Giammarco, A. Calafiore, and R. De Caterina Surgical bleeding after pre-operative unfractionated heparin and low molecular weight heparin for coronary bypass surgery Haematologica, March 1, 2007; 92(3): 366 - 373. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Burris, K. Schwartz, C.-M. Tang, M. S. Jafri, J. Schmitt, M. H. Kwon, O. Toshinaga, J. Gu, J. Brown, E. Brown, et al. Catheter-based infrared light scanner as a tool to assess conduit quality in coronary artery bypass surgery J. Thorac. Cardiovasc. Surg., February 1, 2007; 133(2): 419 - 427. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Schachner, G. Laufer, and J. Bonatti In vivo (animal) models of vein graft disease. Eur. J. Cardiothorac. Surg., September 1, 2006; 30(3): 451 - 463. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Rigatelli, M. Giordan, P. Cardaioli, L. Roncon, G. Faggian, G. Rigatelli, and P. Zonzin Subclavian artery angioplasty allows for implantation of the in situ internal thoracic artery graft in patients scheduled for surgical myocardial revascularization J. Thorac. Cardiovasc. Surg., June 1, 2006; 131(6): e9 - e10. [Full Text] [PDF] |
||||
![]() |
T. Schachner Pharmacologic inhibition of vein graft neointimal hyperplasia J. Thorac. Cardiovasc. Surg., May 1, 2006; 131(5): 1065 - 1072. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Gossl and A. Lerman Endothelin: Beyond a Vasoconstrictor Circulation, March 7, 2006; 113(9): 1156 - 1158. [Full Text] [PDF] |
||||
![]() |
J. P. Greelish, S. S. Eagle, D. X. Zhao, R. J. Deegan, M. H. Crenshaw, J. M. Balaguer, R. M. Ahmad, and J. G. Byrne Management of new-onset mitral regurgitation with intraoperative angiography and intraoperative percutaneous coronary intervention J. Thorac. Cardiovasc. Surg., January 1, 2006; 131(1): 239 - 240. [Full Text] [PDF] |
||||
![]() |
PREVENT IV Investigators Efficacy and Safety of Edifoligide, an E2F Transcription Factor Decoy, for Prevention of Vein Graft Failure Following Coronary Artery Bypass Graft Surgery: PREVENT IV: A Randomized Controlled Trial JAMA, November 16, 2005; 294(19): 2446 - 2454. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Kitamura, H. Okabayashi, M. Hanyu, Y. Soga, T. Nomoto, H. Johno, J. Nakano, T. Matsuo, M. Kai, and E. Umehara Early and midterm patency of the proximal anastomoses of saphenous vein grafts made with a Symmetry Aortic Connector System J. Thorac. Cardiovasc. Surg., October 1, 2005; 130(4): 1028 - 1031. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. H. Jones The Year in Cardiovascular Surgery J. Am. Coll. Cardiol., May 3, 2005; 45(9): 1517 - 1528. [Full Text] [PDF] |
||||
![]() |
PREVENT IV Investigators Efficacy and Safety of Edifoligide, an E2F Transcription Factor Decoy, for Prevention of Vein Graft Failure Following Coronary Artery Bypass Graft Surgery: PREVENT IV: A Randomized Controlled Trial JAMA, November 16, 2005; 294(19): 2446 - 2454. [Abstract] [Full Text] [PDF] |
||||
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |