CLINICAL RESEARCH: ELECTROPHYSIOLOGY
A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate
Koonlawee Nademanee, MD, FACC*,*,
John McKenzie, MD*,
Erol Kosar, MD*,
Mark Schwab, MD*,
Buncha Sunsaneewitayakul, MD ,
Thaveekiat Vasavakul, MD*,
Chotikorn Khunnawat, MD* and
Tachapong Ngarmukos, MD
* Pacific Rim Electrophysiology Research Institute, Inglewood, California, USA
Chulalongkorn University, Bangkok, Thailand
Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Manuscript received September 23, 2003;
revised manuscript received December 9, 2003,
accepted December 15, 2003.
* Reprint requests and correspondence: Dr. Koonlawee Nademanee, Pacific Rim Electrophysiology Research Institute, 575 East Hardy Street, Suite 201, Inglewood, California 90301, USA.
wee{at}pacificrimep.com
OBJECTIVES: We sought to test the hypothesis that complex fractionated electrograms (CFAEs) recorded during atrial fibrillation (AF) could be used as target sites for catheter ablation of AF.
BACKGROUND: Mapping of AF in humans has shown that areas of CFAEs correlate with areas of slowed conduction and pivot points of reentrant wavelets. We hypothesized that such areas of CFAEs could be identified in patients with AF and might serve as target sites for catheter ablation to maintain sinus rhythm.
METHODS: The study population included 121 patients (29 females; mean age, 63 years) with refractory AF (57 paroxysmal, 64 chronic). All patients underwent nonfluoroscopic electroanatomic mapping (CARTO) during AF. Using CARTO, the biatrial replica, displayed in a three-dimensional color-coded voltage map, was created during AF, and areas associated with CFAEs were identified. Radiofrequency ablation of the area with CFAEs was performed, aiming to eliminate CFAE and/or convert to sinus rhythm.
RESULTS: Complex fractionated atrial electrograms were found in seven of nine regions of both atria, but were mainly confined to the interatrial septum, pulmonary veins, roof of left atrium, and left posteroseptal mitral annulus and coronary sinus ostium. Ablations of the areas associated with CFAEs resulted in termination of AF without external cardioversion in 115 of the 121 patients (95%); 32 (28%) required concomitant ibutilide treatment. At the one-year follow-up, 110 (91%) patients were free of arrhythmia and symptoms, 92 after one ablation and 18 after two.
CONCLUSIONS: Areas with CFAEs represent a defined electrophysiologic substrate and are ideal target sites for ablations to eliminate AF and maintain normal sinus rhythm.
|
Abbreviations and Acronyms
| | AF | = atrial fibrillation | | CAF | = chronic atrial fibrillation | | CARTO | = electroanatomic mapping | | CFAEs | = complex fractionated atrial electrograms | | CS | = coronary sinus | | LIPV | = left inferior pulmonary vein | | LSPV | = left superior pulmonary vein | | PAF | = paroxysmal atrial fibrillation | | RIPV | = right inferior pulmonary vein | | RSPV | = right superior pulmonary vein |
|
This article has been cited by other articles:
|
|
|
|
 
R. Cappato
NICE guidance on catheter ablation of atrial fibrillation using an epicardial (non-thorascopic) approach
Heart,
December 1, 2009;
95(23):
1956 - 1957.
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Bertaglia, C. Tondo, A. De Simone, F. Zoppo, M. Mantica, P. Turco, A. Iuliano, G. Forleo, V. La Rocca, and G. Stabile
Does catheter ablation cure atrial fibrillation? Single-procedure outcome of drug-refractory atrial fibrillation ablation: a 6-year multicentre experience
Europace,
November 3, 2009;
(2009)
eup349v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
X Wang, X Liu, H Shi, J Gu, Y Sun, L Zhou, and W Hu
Pulmonary vein isolation combined with substrate modification for persistent atrial fibrillation treatment in patients with valvular heart diseases
Heart,
November 1, 2009;
95(21):
1773 - 1783.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. W. Davies and M. D O'Neill
What now for atrial fibrillation ablation?
Heart,
November 1, 2009;
95(21):
1723 - 1724.
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Shamiss, Y. Khaykin, R. Oosthuizen, D. Tunney, B. Sarak, M. Beardsall, C. Seabrook, L. Frost, Z. Wulffhart, B. Tsang, et al.
Dofetilide is safe and effective in preventing atrial fibrillation recurrences in patients accepted for catheter ablation
Europace,
November 1, 2009;
11(11):
1448 - 1455.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. P. Redfearn, C. S. Simpson, H. Abdollah, and A. M. Baranchuk
Temporo-spatial stability of complex fractionated atrial electrograms in two distinct and separate episodes of paroxysmal atrial fibrillation
Europace,
November 1, 2009;
11(11):
1440 - 1444.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. De Potter, A. Berruezo, L. Mont, M. Matiello, D. Tamborero, C. Santibanez, B. Benito, N. Zamorano, and J. Brugada
Left ventricular systolic dysfunction by itself does not influence outcome of atrial fibrillation ablation
Europace,
October 31, 2009;
(2009)
eup309v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Scharf, L. Boersma, W. Davies, P. Kanagaratnam, N. S. Peters, V. Paul, E. Rowland, A. Grace, S. Fynn, L. Dang, et al.
Ablation of Persistent Atrial Fibrillation Using Multielectrode Catheters and Duty-Cycled Radiofrequency Energy
J. Am. Coll. Cardiol.,
October 6, 2009;
54(15):
1450 - 1456.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Khaykin, A. Skanes, J. Champagne, S. Themistoclakis, L. Gula, A. Rossillo, A. Bonso, A. Raviele, C. A. Morillo, A. Verma, et al.
A Randomized Controlled Trial of the Efficacy and Safety of Electroanatomic Circumferential Pulmonary Vein Ablation Supplemented by Ablation of Complex Fractionated Atrial Electrograms Versus Potential-Guided Pulmonary Vein Antrum Isolation Guided by Intracardiac Ultrasound
Circ Arrhythm Electrophysiol,
October 1, 2009;
2(5):
481 - 487.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Matsuo, N. Lellouche, M. Wright, M. Bevilacqua, S. Knecht, I. Nault, K.-T. Lim, L. Arantes, M. D. O'Neill, P. G. Platonov, et al.
Clinical predictors of termination and clinical outcome of catheter ablation for persistent atrial fibrillation.
J. Am. Coll. Cardiol.,
August 25, 2009;
54(9):
788 - 795.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Niu, B. J. Scherlag, Z. Lu, M. Ghias, Y. Zhang, E. Patterson, T. W. Dasari, S. Zacharias, R. Lazzara, W. M. Jackman, et al.
An Acute Experimental Model Demonstrating 2 Different Forms of Sustained Atrial Tachyarrhythmias
Circ Arrhythm Electrophysiol,
August 1, 2009;
2(4):
384 - 392.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. M.S. de Groot
Fractionated extracellular potentials: indicators of the arrhythmogenic substrate?
Europace,
August 1, 2009;
11(8):
975 - 976.
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Bencsik, M. Martinek, S. Hassanein, J. Aichinger, H.-J. Nesser, and H. Purerfellner
Acute effects of complex fractionated atrial electrogram ablation on dominant frequency and regulatory index for the fibrillatory process
Europace,
August 1, 2009;
11(8):
1011 - 1017.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Bortone, S. Boveda, J.-L. Pasquie, P. Pujadas-Berthault, E. Marijon, A. Appetiti, and J.-P. Albenque
Sinus rhythm restoration by catheter ablation in patients with long-lasting atrial fibrillation and congestive heart failure: impact of the left ventricular ejection fraction improvement on the implantable cardioverter defibrillator insertion indication
Europace,
August 1, 2009;
11(8):
1018 - 1023.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. R. Edgerton, J. H. McClelland, D. Duke, M. W. Gerdisch, B. M. Steinberg, S. H. Bronleewe, S. L. Prince, M. A. Herbert, S. Hoffman, and M. J. Mack
Minimally invasive surgical ablation of atrial fibrillation: Six-month results
J. Thorac. Cardiovasc. Surg.,
July 1, 2009;
138(1):
109 - 114.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Kirchhof, J. Bax, C. Blomstrom-Lundquist, H. Calkins, A. J. Camm, R. Cappato, F. Cosio, H. Crijns, H.-C. Diener, A. Goette, et al.
Early and comprehensive management of atrial fibrillation: Proceedings from the 2nd AFNET/EHRA consensus conference on atrial fibrillation entitled 'research perspectives in atrial fibrillation'
Europace,
July 1, 2009;
11(7):
860 - 885.
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. A. Crandall, D. J. Bradley, D. L. Packer, and S. J. Asirvatham
Contemporary Management of Atrial Fibrillation: Update on Anticoagulation and Invasive Management Strategies
Mayo Clin. Proc.,
July 1, 2009;
84(7):
643 - 662.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. B. Forleo and C. Tondo
Atrial fibrillation: cure or treat?
Therapeutic Advances in Cardiovascular Disease,
June 1, 2009;
3(3):
187 - 196.
[Abstract]
[PDF]
|
|
|
|
|
|
|
Y.-J. Lin, C.-T. Tai, T. Kao, S.-L. Chang, L.-W. Lo, T.-C. Tuan, A. R. Udyavar, W. Wongcharoen, Y.-F. Hu, H.-W. Tso, et al.
Spatiotemporal Organization of the Left Atrial Substrate After Circumferential Pulmonary Vein Isolation of Atrial Fibrillation
Circ Arrhythm Electrophysiol,
June 1, 2009;
2(3):
233 - 241.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. D. O'Neill, M. Wright, S. Knecht, P. Jais, M. Hocini, Y. Takahashi, A. Jonsson, F. Sacher, S. Matsuo, K. T. Lim, et al.
Long-term follow-up of persistent atrial fibrillation ablation using termination as a procedural endpoint
Eur. Heart J.,
May 1, 2009;
30(9):
1105 - 1112.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Rajappan, V. Baker, L. Richmond, P. M. Kistler, G. Thomas, C. Redpath, S. C. Sporton, M. J. Earley, S. Harris, and R. J. Schilling
A randomized trial to compare atrial fibrillation ablation using a steerable vs. a non-steerable sheath
Europace,
May 1, 2009;
11(5):
571 - 575.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Di Biase, L. C. Saenz, D. J. Burkhardt, M. Vacca, C. S. Elayi, C. D. Barrett, R. Horton, R. Bai, A. Siu, T. S. Fahmy, et al.
Esophageal Capsule Endoscopy After Radiofrequency Catheter Ablation for Atrial Fibrillation: Documented Higher Risk of Luminal Esophageal Damage With General Anesthesia as Compared With Conscious Sedation
Circ Arrhythm Electrophysiol,
April 1, 2009;
2(2):
108 - 112.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. Schmidt, R. R. Tilz, K. Neven, K.R. Julian Chun, A. Furnkranz, and F. Ouyang
Remote Robotic Navigation and Electroanatomical Mapping for Ablation of Atrial Fibrillation: Considerations for Navigation and Impact on Procedural Outcome
Circ Arrhythm Electrophysiol,
April 1, 2009;
2(2):
120 - 128.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Di Biase, C. S. Elayi, T. S. Fahmy, D. O. Martin, C. K. Ching, C. Barrett, R. Bai, D. Patel, Y. Khaykin, R. Hongo, et al.
Atrial Fibrillation Ablation Strategies for Paroxysmal Patients: Randomized Comparison Between Different Techniques
Circ Arrhythm Electrophysiol,
April 1, 2009;
2(2):
113 - 119.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R Balasubramaniam and P M Kistler
Atrial fibrillation in heart failure: the chicken or the egg?
Heart,
April 1, 2009;
95(7):
535 - 539.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Oral, A. Chugh, K. Yoshida, J. F. Sarrazin, M. Kuhne, T. Crawford, N. Chalfoun, D. Wells, W. Boonyapisit, S. Veerareddy, et al.
A randomized assessment of the incremental role of ablation of complex fractionated atrial electrograms after antral pulmonary vein isolation for long-lasting persistent atrial fibrillation.
J. Am. Coll. Cardiol.,
March 3, 2009;
53(9):
782 - 789.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Nademanee and N. Oketani
The role of complex fractionated atrial electrograms in atrial fibrillation ablation moving to the beat of a different drum.
J. Am. Coll. Cardiol.,
March 3, 2009;
53(9):
790 - 791.
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. F. Berntsen, A. Cheng, H. Calkins, and R. D. Berger
Evaluation of spatiotemporal organization of persistent atrial fibrillation with time- and frequency-domain measures in humans
Europace,
March 1, 2009;
11(3):
316 - 323.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Katritsis, E. Giazitzoglou, D. Sougiannis, E. Voridis, and S. S. Po
Complex fractionated atrial electrograms at anatomic sites of ganglionated plexi in atrial fibrillation
Europace,
March 1, 2009;
11(3):
308 - 315.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Tamborero, L. Mont, A. Berruezo, M. Matiello, B. Benito, M. Sitges, B. Vidal, T. M. de Caralt, R. J. Perea, R. Vatasescu, et al.
Left Atrial Posterior Wall Isolation Does Not Improve the Outcome of Circumferential Pulmonary Vein Ablation for Atrial Fibrillation: A Prospective Randomized Study
Circ Arrhythm Electrophysiol,
February 1, 2009;
2(1):
35 - 40.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Ernst
The future of atrial fibrillation ablation: new technologies and indications: Atrial fibrillation
Heart,
January 15, 2009;
95(2):
158 - 163.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J.#x.;n. Farré, H. J.J. Wellens, J.#x. M. Rubio, and J. Benezet
CHAPTER 28 Supraventricular Tachycardias
ESC Textbook of Cardiovascular Medicine,
January 1, 2009;
2(1):
med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. J. Camm, P. Kirchhof, G. Y.H. Lip, I. Savelieva, and S. Ernst
CHAPTER 29 Atrial Fibrillation
ESC Textbook of Cardiovascular Medicine,
January 1, 2009;
2(1):
med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Jais, B. Cauchemez, L. Macle, E. Daoud, P. Khairy, R. Subbiah, M. Hocini, F. Extramiana, F. Sacher, P. Bordachar, et al.
Catheter Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation: The A4 Study
Circulation,
December 9, 2008;
118(24):
2498 - 2505.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Bajpai, I. Savelieva, and A. J. Camm
Treatment of atrial fibrillation
Br. Med. Bull.,
December 5, 2008;
(2008)
ldn046v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. M. Kistler, K. Rajappan, S. Harris, M. J. Earley, L. Richmond, S. C. Sporton, and R. J. Schilling
The impact of image integration on catheter ablation of atrial fibrillation using electroanatomic mapping: a prospective randomized study
Eur. Heart J.,
December 2, 2008;
29(24):
3029 - 3036.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Dixit
Evolving Strategies in Catheter Ablation of Long-Standing Atrial Fibrillation
Circ Arrhythm Electrophysiol,
December 1, 2008;
1(5):
324 - 326.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Rostock, D. Steven, B. Hoffmann, H. Servatius, I. Drewitz, K. Sydow, K. Mullerleile, R. Ventura, K. Wegscheider, T. Meinertz, et al.
Chronic Atrial Fibrillation Is a Biatrial Arrhythmia: Data from Catheter Ablation of Chronic Atrial Fibrillation Aiming Arrhythmia Termination Using a Sequential Ablation Approach
Circ Arrhythm Electrophysiol,
December 1, 2008;
1(5):
344 - 353.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. L. Estner, G. Hessling, G. Ndrepepa, J. Wu, T. Reents, S. Fichtner, C. Schmitt, C. V. Bary, C. Kolb, M. Karch, et al.
Electrogram-guided substrate ablation with or without pulmonary vein isolation in patients with persistent atrial fibrillation
Europace,
November 1, 2008;
10(11):
1281 - 1287.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Knecht, I. Nault, M. Wright, S. Matsuo, N. Lellouche, P. E. Somasundaram, M. D. O'Neill, K.-T. Lim, F. Sacher, A. Deplagne, et al.
Imaging in catheter ablation for atrial fibrillation: enhancing the clinician's view
Europace,
November 1, 2008;
10(suppl_3):
iii2 - iii7.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Knackstedt, P. Schauerte, and P. Kirchhof
Electro-anatomic mapping systems in arrhythmias
Europace,
November 1, 2008;
10(suppl_3):
iii28 - iii34.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Niinuma, R. T. George, A. Arbab-Zadeh, J. A.C. Lima, and C. A. Henrikson
Imaging of pulmonary veins during catheter ablation for atrial fibrillation: the role of multi-slice computed tomography
Europace,
November 1, 2008;
10(suppl_3):
iii14 - iii21.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. J. McGann, E. G. Kholmovski, R. S. Oakes, J. J.E. Blauer, M. Daccarett, N. Segerson, K. J. Airey, N. Akoum, E. Fish, T. J. Badger, et al.
New Magnetic Resonance Imaging-Based Method for Defining the Extent of Left Atrial Wall Injury After the Ablation of Atrial Fibrillation
J. Am. Coll. Cardiol.,
October 7, 2008;
52(15):
1263 - 1271.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. R. Halperin and S. Nazarian
Damage Assessment After Ablation: Role of Cardiovascular Magnetic Resonance
J. Am. Coll. Cardiol.,
October 7, 2008;
52(15):
1272 - 1273.
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Calkins
Further Insight into the Technique and Outcomes of "Curative" Catheter Ablation of Atrial Fibrillation
Circ Arrhythm Electrophysiol,
October 1, 2008;
1(4):
238 - 239.
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. Gaita, D. Caponi, M. Scaglione, A. Montefusco, A. Corleto, F. Di Monte, D. Coin, P. Di Donna, and C. Giustetto
Long-Term Clinical Results of 2 Different Ablation Strategies in Patients With Paroxysmal and Persistent Atrial Fibrillation
Circ Arrhythm Electrophysiol,
October 1, 2008;
1(4):
269 - 275.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Li, Y. Li, L. Sun, X. Liu, C. Xu, J. Han, and X. Meng
Minimally Invasive Surgical Pulmonary Vein Isolation Alone for Persistent Atrial Fibrillation: Preliminary Results of Epicardial Atrial Electrogram Analysis
Ann. Thorac. Surg.,
October 1, 2008;
86(4):
1219 - 1225.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Nitta
Invited Commentary
Ann. Thorac. Surg.,
October 1, 2008;
86(4):
1225 - 1226.
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Knecht, M. Hocini, M. Wright, N. Lellouche, M. D. O'Neill, S. Matsuo, I. Nault, V. S. Chauhan, K. J. Makati, M. Bevilacqua, et al.
Left atrial linear lesions are required for successful treatment of persistent atrial fibrillation
Eur. Heart J.,
October 1, 2008;
29(19):
2359 - 2366.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y Blaauw and H J G M Crijns
Treatment of atrial fibrillation
Heart,
October 1, 2008;
94(10):
1342 - 1349.
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Proclemer, G. Allocca, D. Gregori, C. Bonanno, R. Ometto, A. Fontanelli, R. Mantovan, M. Crosato, V. Calzolari, D. Pavoni, et al.
Radiofrequency ablation of drug-refractory atrial fibrillation: an observational study comparing 'ablate and pace' with pulmonary vein isolation
Europace,
September 1, 2008;
10(9):
1085 - 1090.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Aliot and J. N. Ruskin
Controversies in ablation of atrial fibrillation
Eur. Heart J. Suppl.,
September 1, 2008;
10(suppl_H):
H32 - H54.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. F Tops and M. J Schalij
Multislice CT: is it essential before atrial fibrillation ablation?
Heart,
August 1, 2008;
94(8):
973 - 975.
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Knecht, H. Skali, M. D. O'Neill, M. Wright, S. Matsuo, G. M. Chaudhry, C. I. Haffajee, I. Nault, G. H.M. Gijsbers, F. Sacher, et al.
Computed tomography-fluoroscopy overlay evaluation during catheter ablation of left atrial arrhythmia
Europace,
August 1, 2008;
10(8):
931 - 938.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Takahashi, M. Shoda, T. Manaka, and T. Nakanishi
Successful radiofrequency catheter ablation of atrial fibrillation late after modified Fontan operation
Europace,
August 1, 2008;
10(8):
1012 - 1014.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. G. Katritsis
Catheter Ablation of Atrial Fibrillation: For Whom and How?
Angiology,
August 1, 2008;
59(2_suppl):
103S - 106S.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. R. Edgerton, Z. J. Edgerton, T. Weaver, K. Reed, S. Prince, M. A. Herbert, and M. J. Mack
Minimally Invasive Pulmonary Vein Isolation and Partial Autonomic Denervation for Surgical Treatment of Atrial Fibrillation
Ann. Thorac. Surg.,
July 1, 2008;
86(1):
35 - 39.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Liang, Q. Pan, Y. Liu, H. Chen, J. Li, R. Brugada, P. Brugada, K. Hong, G. J. Perez, C. Zhao, et al.
High sensitivity of the sheep pulmonary vein antrum to acetylcholine stimulation
J Appl Physiol,
July 1, 2008;
105(1):
293 - 298.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W. Saliba, V. Y. Reddy, O. Wazni, J. E. Cummings, J. D. Burkhardt, M. Haissaguerre, J. Kautzner, P. Peichl, P. Neuzil, V. Schibgilla, et al.
Atrial fibrillation ablation using a robotic catheter remote control system initial human experience and long-term follow-up results.
J. Am. Coll. Cardiol.,
June 24, 2008;
51(25):
2407 - 2411.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. A Lubitz, A. Fischer, and V. Fuster
Catheter ablation for atrial fibrillation
BMJ,
April 12, 2008;
336(7648):
819 - 826.
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Steven, T. Rostock, B. Lutomsky, H. Klemm, H. Servatius, I. Drewitz, K. Friedrichs, R. Ventura, T. Meinertz, and S. Willems
What is the real atrial fibrillation burden after catheter ablation of atrial fibrillation? A prospective rhythm analysis in pacemaker patients with continuous atrial monitoring
Eur. Heart J.,
April 2, 2008;
29(8):
1037 - 1042.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Haissaguerre, M. Wright, M. Hocini, and P. Jais
The Substrate Maintaining Persistent Atrial Fibrillation
Circ Arrhythm Electrophysiol,
April 1, 2008;
1(1):
2 - 5.
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Oral, A. Chugh, E. Good, T. Crawford, J. F. Sarrazin, M. Kuhne, N. Chalfoun, D. Wells, W. Boonyapisit, N. Gadeela, et al.
Randomized Evaluation of Right Atrial Ablation After Left Atrial Ablation of Complex Fractionated Atrial Electrograms for Long-Lasting Persistent Atrial Fibrillation
Circ Arrhythm Electrophysiol,
April 1, 2008;
1(1):
6 - 13.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. M. Patel, A. d'Avila, P. Neuzil, S. J. Kim, MSEE, T. Mela, J. P. Singh, J. N. Ruskin, and V. Y. Reddy
Atrial Tachycardia After Ablation of Persistent Atrial Fibrillation: Identification of the Critical Isthmus With a Combination of Multielectrode Activation Mapping and Targeted Entrainment Mapping
Circ Arrhythm Electrophysiol,
April 1, 2008;
1(1):
14 - 22.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. R. Betts
Atrioventricular junction ablation and pacemaker implant for atrial fibrillation: still a valid treatment in appropriately selected patients
Europace,
April 1, 2008;
10(4):
425 - 432.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Takahashi, M. D. O'Neill, M. Hocini, R. Dubois, S. Matsuo, S. Knecht, S. Mahapatra, K.-T. Lim, P. Jais, A. Jonsson, et al.
Characterization of electrograms associated with termination of chronic atrial fibrillation by catheter ablation.
J. Am. Coll. Cardiol.,
March 11, 2008;
51(10):
1003 - 1010.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. E. Marchlinski
Atrial fibrillation catheter ablation: learning by burning continues.
J. Am. Coll. Cardiol.,
March 11, 2008;
51(10):
1011 - 1013.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Chen, M. K. Off, E. Solheim, P. Schuster, P. I. Hoff, and O.-J. Ohm
Treatment of atrial fibrillation by silencing electrical activity in the posterior inter-pulmonary-vein atrium
Europace,
March 1, 2008;
10(3):
265 - 272.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Nademanee, M. C. Schwab, E. M. Kosar, M. Karwecki, M. D. Moran, N. Visessook, A. D. Michael, and T. Ngarmukos
Clinical Outcomes of Catheter Substrate Ablation for High-Risk Patients With Atrial Fibrillation
J. Am. Coll. Cardiol.,
February 26, 2008;
51(8):
843 - 849.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. C. Roberts-Thomson, I. H. Stevenson, P. M. Kistler, H. M. Haqqani, J. C. Goldblatt, P. Sanders, and J. M. Kalman
Anatomically Determined Functional Conduction Delay in the Posterior Left Atrium: Relationship to Structural Heart Disease
J. Am. Coll. Cardiol.,
February 26, 2008;
51(8):
856 - 862.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. P. Gerstenfeld
Functional Block in the Posterior Left Atrium: Another Piece in the Puzzle of Atrial Fibrillation Initiation
J. Am. Coll. Cardiol.,
February 26, 2008;
51(8):
863 - 864.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. A. Cabrera, S. Y. Ho, V. Climent, and D. Sanchez-Quintana
The architecture of the left lateral atrial wall: a particular anatomic region with implications for ablation of atrial fibrillation
Eur. Heart J.,
February 1, 2008;
29(3):
356 - 362.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Schmidt, G. Nolker, H. Marschang, K.-J. Gutleben, V. Schibgilla, H. Rittger, A.-M. Sinha, G. Ritscher, D. Mayer, J. Brachmann, et al.
Incidence of oesophageal wall injury post-pulmonary vein antrum isolation for treatment of patients with atrial fibrillation
Europace,
February 1, 2008;
10(2):
205 - 209.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. N. DeMaria, J. J. Bax, O. Ben-Yehuda, P. Clopton, G. K. Feld, G. S. Ginsburg, B. H. Greenberg, J. D. Knoke, W. Y.W. Lew, J. A.C. Lima, et al.
Highlights of the year in JACC 2007.
J. Am. Coll. Cardiol.,
January 29, 2008;
51(4):
490 - 512.
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. E. Eckart and L. M. Epstein
Interventional Therapy for Atrial and Ventricular Arrhythmias
Card. Surg. Adult,
January 1, 2008;
3(2008):
1357 - 1374.
[Full Text]
|
|
|
|
|
|
|
F. G. Cosio, E. Aliot, G. L. Botto, H. Heidbuchel, C. J. Geller, P. Kirchhof, J.-C. De Haro, R. Frank, J. P. Villacastin, J. Vijgen, et al.
Delayed rhythm control of atrial fibrillation may be a cause of failure to prevent recurrences: reasons for change to active antiarrhythmic treatment at the time of the first detected episode
Europace,
January 1, 2008;
10(1):
21 - 27.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
