JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
 QUICK SEARCH:   [advanced]


     


J Am Coll Cardiol, 2002; 39:1151-1158
© 2002 by the American College of Cardiology Foundation
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Allman, K. C.
Right arrow Articles by Udelson, J. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Allman, K. C.
Right arrow Articles by Udelson, J. E.

CLINICAL STUDY: CORONARY REVASCULARIZATION

Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: a meta-analysis

Kevin C. Allman, MB, BS, FRACP, FACC*,*, Leslee J. Shaw, PhD{dagger}, Rory Hachamovitch, MD, FACC{dagger} and James E. Udelson, MD, FACC{ddagger}

* Concord Hospital, Concord NSW, Australia
{dagger} Atlanta Cardiovascular Research Institute, Atlanta, Georgia, USA
{ddagger} Tufts University School of Medicine/New England Medical Center Hospitals, Boston, Massachusetts, USA

Manuscript received May 22, 2001; revised manuscript received October 10, 2001, accepted January 10, 2002.

* Reprint requests and correspondence: Kevin C. Allman, Nuclear Cardiology Laboratory, Concord Hospital, Concord 2139, Australia
kevina{at}nucmed.crg.cs.nsw.gov.au

OBJECTIVES: This study pools data from published series examining late survival with revascularization versus medical therapy after myocardial viability testing in patients with severe coronary artery disease (CAD) and left ventricular (LV) dysfunction.

BACKGROUND: Previous observational studies have suggested survival benefit in such patients if they are revascularized when myocardial viability is detected on imaging tests.

METHODS: A MEDLINE database search returned 24 viability studies reporting patient survival using thallium perfusion imaging, F-18 fluorodeoxyglucose metabolic imaging or dobutamine echocardiography. Annual death rates were extracted, pooled and analyzed with a random effects model. The risk-adjusted relationship between severity of LV dysfunction, presence of viability and survival benefit associated with revascularization was assessed by meta-regression.

RESULTS: There were 3,088 patients (2,228 men), ejection fraction 32 ± 8%, followed for 25 ± 10 months. In patients with viability, revascularization was associated with 79.6% reduction in annual mortality (16% vs. 3.2%, chi-square = 147, p < 0.0001) compared with medical treatment. Patients without viability had intermediate mortality, trending to higher rates with revascularization versus medical therapy (7.7% vs. 6.2%, p = NS). Patients with viability showed a direct relationship between severity of LV dysfunction and magnitude of benefit with revascularization (p < 0.001). There was no measurable performance difference for predicting revascularization benefit between the three testing techniques.

CONCLUSIONS: This meta-analysis demonstrates a strong association between myocardial viability on noninvasive testing and improved survival after revascularization in patients with chronic CAD and LV dysfunction. Absence of viability was associated with no significant difference in outcomes, irrespective of treatment strategy.

Abbreviations and Acronyms
  CAD
  coronary artery disease
  DASE
  dobutamine/atropine stress echocardiography
  EF
  ejection fraction
  FDG
  F-18 fluorodeoxyglucose
  LDDE
  low-dose dobutamine echocardiography
  LV
  left ventricular
  LVEF
  left ventricular ejection fraction
  NYHA
  New York Heart Association
  PET
  positron emission tomography
  RALES
  Randomized Spironolactone Evaluation study
  SPECT
  single photon emission computed tomography




This article has been cited by other articles:


Home page
Eur Heart JHome page
S. Ghostine, C. Caussin, M. Habis, Y. Habib, C. Clement, A. Sigal-Cinqualbre, C.-Y. Angel, B. Lancelin, A. Capderou, and J.-F. Paul
Non-invasive diagnosis of ischaemic heart failure using 64-slice computed tomography
Eur. Heart J., September 1, 2008; 29(17): 2133 - 2140.
[Abstract] [Full Text] [PDF]


Home page
JNMHome page
X. Zhang, X.-j. Liu, S. Hu, T. H. Schindler, Y. Tian, Z.-x. He, R. Gao, Q. Wu, H. Wei, J. W. Sayre, et al.
Long-Term Survival of Patients with Viable and Nonviable Aneurysms Assessed by 99mTc-MIBI SPECT and 18F-FDG PET: A Comparative Study of Medical and Surgical Treatment
J. Nucl. Med., August 1, 2008; 49(8): 1288 - 1298.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll Cardiol ImgHome page
S. H. Rahimtoola, V. Dilsizian, C. M. Kramer, T. H. Marwick, and J.-L. J. Vanoverschelde
Chronic Ischemic Left Ventricular Dysfunction: From Pathophysiology to Imaging and its Integration Into Clinical Practice
J. Am. Coll. Cardiol. Img., July 1, 2008; 1(4): 536 - 555.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
J. Chan, F. Khafagi, A. A. Young, B. R. Cowan, C. Thompson, and T. H. Marwick
Impact of coronary revascularization and transmural extent of scar on regional left ventricular remodelling
Eur. Heart J., July 1, 2008; 29(13): 1608 - 1617.
[Abstract] [Full Text] [PDF]


Home page
Eur J EchocardiogrHome page
R. Sicari, P. Nihoyannopoulos, A. Evangelista, J. Kasprzak, P. Lancellotti, D. Poldermans, J.-U. Voigt, J. L. Zamorano, and on behalf of the European Association of Echocardi
Stress echocardiography expert consensus statement: European Association of Echocardiography (EAE) (a registered branch of the ESC)
Eur J Echocardiogr, July 1, 2008; 9(4): 415 - 437.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
G. T. O'Connor, E. M. Olmstead, W. C. Nugent, B. J. Leavitt, R. A. Clough, P. W. Weldner, D. C. Charlesworth, K. Chaisson, D. Sisto, E. R. Nowicki, et al.
Appropriateness of coronary artery bypass graft surgery performed in northern New England.
J. Am. Coll. Cardiol., June 17, 2008; 51(24): 2323 - 2328.
[Abstract] [Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
D. D. Potter, P. A. Araoz, K. P. McGee, W. S. Harmsen, J. N. Mandrekar, and T. M. Sundt III
Low-dose dobutamine cardiac magnetic resonance imaging with myocardial strain analysis predicts myocardial recoverability after coronary artery bypass grafting.
J. Thorac. Cardiovasc. Surg., June 1, 2008; 135(6): 1342 - 1347.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
D. D. Schocken, E. J. Benjamin, G. C. Fonarow, H. M. Krumholz, D. Levy, G. A. Mensah, J. Narula, E. S. Shor, J. B. Young, and Y. Hong
Prevention of Heart Failure: A Scientific Statement From the American Heart Association Councils on Epidemiology and Prevention, Clinical Cardiology, Cardiovascular Nursing, and High Blood Pressure Research; Quality of Care and Outcomes Research Interdisciplinary Working Group; and Functional Genomics and Translational Biology Interdisciplinary Working Group
Circulation, May 13, 2008; 117(19): 2544 - 2565.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
J Knuuti and F M Bengel
Positron emission tomography and molecular imaging
Heart, March 1, 2008; 94(3): 360 - 367.
[Abstract] [Full Text] [PDF]


Home page
Card Surg AdultHome page
M. L. Brown, T. M. Sundt III, and B. J. Gersh
Indications for Revascularization
Card. Surg. Adult, January 1, 2008; 3(2008): 551 - 572.
[Full Text]


Home page
CirculationHome page
P. G. Camici, S. K. Prasad, and O. E. Rimoldi
Stunning, Hibernation, and Assessment of Myocardial Viability
Circulation, January 1, 2008; 117(1): 103 - 114.
[Full Text] [PDF]


Home page
J. Thorac. Cardiovasc. Surg.Home page
E. J. Velazquez, K. L. Lee, C. M. O'Connor, J. K. Oh, R. O. Bonow, G. M. Pohost, A. M. Feldman, D. B. Mark, J. A. Panza, G. Sopko, et al.
The rationale and design of the Surgical Treatment for Ischemic Heart Failure (STICH) trial.
J. Thorac. Cardiovasc. Surg., December 1, 2007; 134(6): 1540 - 1547.e4.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
R. S.B. Beanlands, G. Nichol, E. Huszti, D. Humen, N. Racine, M. Freeman, K. Y. Gulenchyn, L. Garrard, R. deKemp, A. Guo, et al.
F-18-Fluorodeoxyglucose Positron Emission Tomography Imaging-Assisted Management of Patients With Severe Left Ventricular Dysfunction and Suspected Coronary Disease: A Randomized, Controlled Trial (PARR-2)
J. Am. Coll. Cardiol., November 13, 2007; 50(20): 2002 - 2012.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
S. Chalil, P. W.X. Foley, S. A. Muyhaldeen, K. C.R. Patel, Z. R. Yousef, R. E.A. Smith, M. P. Frenneaux, and F. Leyva
Late gadolinium enhancement-cardiovascular magnetic resonance as a predictor of response to cardiac resynchronization therapy in patients with ischaemic cardiomyopathy
Europace, November 1, 2007; 9(11): 1031 - 1037.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
M. Penicka, J. Bartunek, O. Lang, K. Medilek, P. Tousek, M. Vanderheyden, B. De Bruyne, M. Maruskova, and P. Widimsky
Severe Left Ventricular Dyssynchrony Is Associated With Poor Prognosis in Patients With Moderate Systolic Heart Failure Undergoing Coronary Artery Bypass Grafting
J. Am. Coll. Cardiol., October 2, 2007; 50(14): 1315 - 1323.
[Abstract] [Full Text] [PDF]


Home page
NEJMHome page
D. G. Katritsis, J. P.A. Ioannidis, T. P. Wharton Jr., V. A. Umans, H. O. Peels, A. P. Shah, D. M. Shavelle, W. J. French, S. De Servi, H. Kiat, et al.
PCI for Stable Coronary Disease
N. Engl. J. Med., July 26, 2007; 357(4): 414 - 418.
[Full Text] [PDF]


Home page
JNMHome page
A. F.L. Schinkel, D. Poldermans, A. Elhendy, and J. J. Bax
Assessment of Myocardial Viability in Patients with Heart Failure
J. Nucl. Med., July 1, 2007; 48(7): 1135 - 1146.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
L. M. Fedoruk, C. G. Tribble, J. A. Kern, B. B. Peeler, and I. L. Kron
Predicting Operative Mortality After Surgery for Ischemic Cardiomyopathy
Ann. Thorac. Surg., June 1, 2007; 83(6): 2029 - 2035.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
C.-M. Yu, J. E. Sanderson, T. H. Marwick, and J. K. Oh
Tissue Doppler Imaging: A New Prognosticator for Cardiovascular Diseases
J. Am. Coll. Cardiol., May 15, 2007; 49(19): 1903 - 1914.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
M. F. Di Carli and R. Hachamovitch
New Technology for Noninvasive Evaluation of Coronary Artery Disease
Circulation, March 20, 2007; 115(11): 1464 - 1480.
[Full Text] [PDF]


Home page
Circ. Res.Home page
V. Bito, J. van der Velden, P. Claus, C. Dommke, A. Van Lommel, L. Mortelmans, E. Verbeken, B. Bijnens, G. Stienen, and K. R. Sipido
Reduced Force Generating Capacity in Myocytes From Chronically Ischemic, Hibernating Myocardium
Circ. Res., February 2, 2007; 100(2): 229 - 237.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
M. Pocar, A. Moneta, A. Grossi, and F. Donatelli
Coronary Artery Bypass for Heart Failure in Ischemic Cardiomyopathy: 17-Year Follow-Up
Ann. Thorac. Surg., February 1, 2007; 83(2): 468 - 474.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
V Rizzello, D Poldermans, A F L Schinkel, E Biagini, E Boersma, A Elhendy, F B Sozzi, A Palazzuoli, A Maat, F Crea, et al.
Outcome after redo coronary artery bypass grafting in patients with ischaemic cardiomyopathy and viable myocardium
Heart, February 1, 2007; 93(2): 221 - 225.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J. J. Mahmarian, L. J. Shaw, N. G. Filipchuk, H. A. Dakik, S. S. Iskander, T. D. Ruddy, M. J. Henzlova, F. Keng, A. Allam, L. A. Moye, et al.
A Multinational Study to Establish the Value of Early Adenosine Technetium-99m Sestamibi Myocardial Perfusion Imaging in Identifying a Low-Risk Group for Early Hospital Discharge After Acute Myocardial Infarction
J. Am. Coll. Cardiol., December 19, 2006; 48(12): 2448 - 2457.
[Abstract] [Full Text] [PDF]


Home page
CMAJHome page
C. B. Marcu, A. M. Beek, and A. C. van Rossum
Clinical applications of cardiovascular magnetic resonance imaging.
Can. Med. Assoc. J., October 10, 2006; 175(8): 911 - 917.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
M. Gheorghiade, G. Sopko, L. De Luca, E. J. Velazquez, J. D. Parker, P. F. Binkley, Z. Sadowski, K. S. Golba, D. L. Prior, J. L. Rouleau, et al.
Navigating the Crossroads of Coronary Artery Disease and Heart Failure
Circulation, September 12, 2006; 114(11): 1202 - 1213.
[Full Text] [PDF]


Home page
CMAJHome page
R. Senior
To revascularize or not to revascularize: a dilemma in heart failure.
Can. Med. Assoc. J., August 15, 2006; 175(4): 372 - 372.
[Full Text] [PDF]


Home page
CirculationHome page
D. Bree, J. R. Wollmuth, B. P. Cupps, M. D. Krock, A. Howells, J. Rogers, N. Moazami, and M. K. Pasque
Low-Dose Dobutamine Tissue-Tagged Magnetic Resonance Imaging With 3-Dimensional Strain Analysis Allows Assessment of Myocardial Viability in Patients With Ischemic Cardiomyopathy
Circulation, July 4, 2006; 114(1_suppl): I-33 - I-36.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
M. Di Mauro, G. Di Giammarco, G. Vitolla, M. Contini, A. L. Iaco, A. Bivona, L. Weltert, and A. M. Calafiore
Impact of No-to-Moderate Mitral Regurgitation on Late Results After Isolated Coronary Artery Bypass Grafting in Patients With Ischemic Cardiomyopathy
Ann. Thorac. Surg., June 1, 2006; 81(6): 2128 - 2134.
[Abstract] [Full Text] [PDF]


Home page
RadiologyHome page
R. M. Setser, J. K. Kim, Y. C. Chung, K. Chen, A. E. Stillman, R. Loeffler, O. P. Simonetti, J. A. Weaver, M. L. Lieber, and R. D. White
Cine Delayed-Enhancement MR Imaging of the Heart: Initial Experience
Radiology, June 1, 2006; 239(3): 856 - 862.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
H. P. Kuhl, C. S.A. Lipke, G. A. Krombach, M. Katoh, T. F. Battenberg, B. Nowak, N. Heussen, A. Buecker, and W. M. Schaefer
Assessment of reversible myocardial dysfunction in chronic ischaemic heart disease: comparison of contrast-enhanced cardiovascular magnetic resonance and a combined positron emission tomography-single photon emission computed tomography imaging protocol
Eur. Heart J., April 1, 2006; 27(7): 846 - 853.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
V Rizzello, D Poldermans, A F L Schinkel, E Biagini, E Boersma, A Elhendy, F B Sozzi, A Maat, F Crea, J R T C Roelandt, et al.
Long term prognostic value of myocardial viability and ischaemia during dobutamine stress echocardiography in patients with ischaemic cardiomyopathy undergoing coronary revascularisation
Heart, February 1, 2006; 92(2): 239 - 244.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
R. J. Gibbons, P. Chareonthaitawee, and K. R. Bailey
Revascularization in Systolic Heart Failure: A Difficult Decision
Circulation, January 17, 2006; 113(2): 180 - 182.
[Full Text] [PDF]


Home page
CirculationHome page
K. G. Tarakji, R. Brunken, P. M. McCarthy, M. O. Al-Chekakie, A. Abdel-Latif, C. E. Pothier, E. H. Blackstone, and M. S. Lauer
Myocardial Viability Testing and the Effect of Early Intervention in Patients With Advanced Left Ventricular Systolic Dysfunction
Circulation, January 17, 2006; 113(2): 230 - 237.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
J. A. Fallavollita, B. J. Riegel, G. Suzuki, U. Valeti, and J. M. Canty Jr.
Mechanism of sudden cardiac death in pigs with viable chronically dysfunctional myocardium and ischemic cardiomyopathy
Am J Physiol Heart Circ Physiol, December 1, 2005; 289(6): H2688 - H2696.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
A. Desideri, L. Cortigiani, A. I. Christen, S. Coscarelli, D. Gregori, P. Zanco, R. Komorovsky, and J. J. Bax
The Extent of Perfusion-F18-Fluorodeoxyglucose Positron Emission Tomography Mismatch Determines Mortality in Medically Treated Patients With Chronic Ischemic Left Ventricular Dysfunction
J. Am. Coll. Cardiol., October 4, 2005; 46(7): 1264 - 1269.
[Abstract] [Full Text] [PDF]


Home page
JNMHome page
M. Schwaiger, S. Ziegler, and S. G. Nekolla
PET/CT: Challenge for Nuclear Cardiology
J. Nucl. Med., October 1, 2005; 46(10): 1664 - 1678.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
V. Ovchinnikov, G. Suzuki, J. M. Canty Jr., and J. A. Fallavollita
Blunted functional responses to pre- and postjunctional sympathetic stimulation in hibernating myocardium
Am J Physiol Heart Circ Physiol, October 1, 2005; 289(4): H1719 - H1728.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
M. Zimarino, A. M. Calafiore, and R. De Caterina
Complete myocardial revascularization: between myth and reality
Eur. Heart J., September 2, 2005; 26(18): 1824 - 1830.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
P. Chareonthaitawee, B. J. Gersh, P. A. Araoz, and R. J. Gibbons
Revascularization in Severe Left Ventricular Dysfunction: The Role of Viability Testing
J. Am. Coll. Cardiol., August 16, 2005; 46(4): 567 - 574.
[Abstract] [Full Text] [PDF]


Home page
JNMHome page
F. M. Bengel
When the Heart Loses Its Nerves...and How Nuclear Imaging Helps to Understand
J. Nucl. Med., August 1, 2005; 46(8): 1252 - 1253.
[Full Text] [PDF]


Home page
JNMHome page
A. J. Luisi Jr., G. Suzuki, R. deKemp, M. S. Haka, S. A. Toorongian, J. M. Canty Jr., and J. A. Fallavollita
Regional 11C-Hydroxyephedrine Retention in Hibernating Myocardium: Chronic Inhomogeneity of Sympathetic Innervation in the Absence of Infarction
J. Nucl. Med., August 1, 2005; 46(8): 1368 - 1374.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
Y. L. Tang, Q. Zhao, X. Qin, L. Shen, L. Cheng, J. Ge, and M. I. Phillips
Paracrine Action Enhances the Effects of Autologous Mesenchymal Stem Cell Transplantation on Vascular Regeneration in Rat Model of Myocardial Infarction
Ann. Thorac. Surg., July 1, 2005; 80(1): 229 - 237.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
G I W Galasko, R Senior, and A Lahiri
Ethnic differences in the prevalence and aetiology of left ventricular systolic dysfunction in the community: the Harrow heart failure watch
Heart, May 1, 2005; 91(5): 595 - 600.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
F Piscione, G Galasso, G De Luca, G Marrazzo, G Sarno, O Viola, D Accardo, and M Chiariello
Late reopening of an occluded infarct related artery improves left ventricular function and long term clinical outcome
Heart, May 1, 2005; 91(5): 646 - 651.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
R Senior, M Monaghan, H Becher, J Mayet, and P Nihoyannopoulos
Stress echocardiography for the diagnosis and risk stratification of patients with suspected or known coronary artery disease: a critical appraisal. Supported by the British Society of Echocardiography
Heart, April 1, 2005; 91(4): 427 - 436.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
V Rizzello, D Poldermans, E Biagini, A F L Schinkel, R van Domburg, A Elhendy, E C Vourvouri, M Bountioukos, A Lombardo, B Krenning, et al.
Improvement of stress LVEF rather than rest LVEF after coronary revascularisation in patients with ischaemic cardiomyopathy and viable myocardium
Heart, March 1, 2005; 91(3): 319 - 323.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
G. Heusch, R. Schulz, and S. H. Rahimtoola
Myocardial hibernation: a delicate balance
Am J Physiol Heart Circ Physiol, March 1, 2005; 288(3): H984 - H999.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
A. Yamaguchi, H. Adachi, K. Kawahito, S. Murata, and T. Ino
Left Ventricular Reconstruction Benefits Patients With Dilated Ischemic Cardiomyopathy
Ann. Thorac. Surg., February 1, 2005; 79(2): 456 - 461.
[Abstract] [Full Text] [PDF]


Home page
JNMHome page
C. Brogsitter, T. Gruning, R. Weise, P. Wielepp, O. Lindner, R. Korfer, and W. Burchert
18F-FDG PET for Detecting Myocardial Viability: Validation of 3D Data Acquisition
J. Nucl. Med., January 1, 2005; 46(1): 19 - 24.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
H Becher, J Chambers, K Fox, R Jones, G J Leech, N Masani, M Monaghan, R More, P Nihoyannopoulos, H Rimington, et al.
BSE procedure guidelines for the clinical application of stress echocardiography, recommendations for performance and interpretation of stress echocardiography: A report of the British Society of Echocardiography Policy Committee
Heart, December 1, 2004; 90(suppl_6): vi23 - vi30.
[Full Text] [PDF]


Home page
CirculationHome page
V. Rizzello, D. Poldermans, E. Boersma, E. Biagini, A. F.L. Schinkel, B. Krenning, A. Elhendy, E. C. Vourvouri, F. B. Sozzi, A. Maat, et al.
Opposite Patterns of Left Ventricular Remodeling After Coronary Revascularization in Patients With Ischemic Cardiomyopathy: Role of Myocardial Viability
Circulation, October 19, 2004; 110(16): 2383 - 2388.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J. J. Bax, A. F.L. Schinkel, E. Boersma, A. Elhendy, V. Rizzello, A. Maat, J. R.T.C. Roelandt, E. E. van der Wall, and D. Poldermans
Extensive Left Ventricular Remodeling Does Not Allow Viable Myocardium to Improve in Left Ventricular Ejection Fraction After Revascularization and Is Associated With Worse Long-Term Prognosis
Circulation, September 14, 2004; 110(11_suppl_1): II-18 - II-22.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
S.R. Underwood, J. J Bax, J. v. Dahl, M. Y Henein, A. C van Rossum, E. R Schwarz, J.-L. Vanoverschelde, E. E.v. d. Wall, and W. Wijns
Imaging techniques for the assessment of myocardial hibernation: Report of a Study Group of the European Society of Cardiology
Eur. Heart J., May 2, 2004; 25(10): 815 - 836.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
G. Heusch and K. R. Sipido
Myocardial Hibernation: A Double-Edged Sword
Circ. Res., April 30, 2004; 94(8): 1005 - 1007.
[Full Text] [PDF]


Home page
Circ. Res.Home page
J. M. Canty Jr, G. Suzuki, M. D. Banas, F. Verheyen, M. Borgers, and J. A. Fallavollita
Hibernating Myocardium: Chronically Adapted to Ischemia but Vulnerable to Sudden Death
Circ. Res., April 30, 2004; 94(8): 1142 - 1149.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
K. Shan, G. Constantine, M. Sivananthan, and S. D. Flamm
Role of Cardiac Magnetic Resonance Imaging in the Assessment of Myocardial Viability
Circulation, March 23, 2004; 109(11): 1328 - 1334.
[Full Text] [PDF]


Home page