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J Am Coll Cardiol, 2002; 39:1026-1032
© 2002 by the American College of Cardiology Foundation
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CLINICAL STUDY: INTERVENTIONAL CARDIOLOGY

Management of coronary artery fistulae

Patient selection and results of transcatheter closure

Laurie R. Armsby, MD*,*, John F. Keane, MD*, Megan C. Sherwood, MBBS, FRACP*, Joseph M. Forbess, MD{dagger}, Stanton B. Perry, MD* and James E. Lock, MD, FACC*

* Department of Cardiology, The Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
{dagger} Department of Cardiovascular Surgery, The Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Manuscript received March 19, 2001; revised manuscript received October 10, 2001, accepted December 21, 2001.

* Reprint requests and correspondence: Dr. Laurie R. Armsby, Department of Cardiology, Children’s Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115 USA.
armsby{at}cardio.tch.harvard.edu

OBJECTIVES: We report short-term findings in 33 patients after transcatheter closure (TCC) of coronary artery fistulae (CAF) and compare our results with those reported in the recent transcatheter and surgical literature.

BACKGROUND: Transcatheter closure of CAF has been advocated as a minimally invasive alternative to surgery.

METHODS: We reviewed all patients presenting with significant CAF between January 1988 and August 2000. Those with additional complex cardiac disease requiring surgical management were excluded.

RESULTS: Of 39 patients considered for TCC, occlusion devices were placed in 33 patients (85%) at 35 procedures and included coils in 28, umbrella devices in 6 and a Grifka vascular occlusion device in 1. Post-deployment angiograms demonstrated complete occlusion in 19, trace in 11, or small residual flow in 5. Follow-up echocardiograms (median, 2.8 years) in 27 patients showed no flow in 22 or small residual flow in 5. Of the 6 patients without follow-up imaging, immediate post-deployment angiograms showed complete occlusion in 5 or small residual flow in 1. Thus, complete occlusion was accomplished in 27 patients (82%). Early complications included transient ST-T wave changes in 5, transient arrhythmias in 4 and single instances of distal coronary artery spasm, fistula dissection and unretrieved coil embolization. There were no deaths or long-term morbidity. Device placement was not attempted in 6 patients (15%), because of multiple fistula drainage sites in 4, extreme vessel tortuosity in 1 and an intracardiac hemangioma in 1.

CONCLUSIONS: A comparison of our results with those in the recent transcatheter and surgical literature shows similar early effectiveness, morbidity and mortality. From data available, TCC of CAF is an acceptable alternative to surgery in most patients.

Abbreviations and Acronyms
  TCC
  CAF
  coronary artery fistulae
  Cx
  circumflex
  ECG
  electrocardiogram
  LAD
  left anterior descending
  LCA
  left coronary artery
  LV
  left ventricle
  RA
  right atrium
  RCA
  right coronary artery
  RV
  right ventricle
  TCC
  transcatheter closure




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