JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
QUICK SEARCH:   [advanced]


     

J Am Coll Cardiol, 2001; 38:1718-1724
© 2001 by the American College of Cardiology Foundation
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wyse, D. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wyse, D. G.

CLINICAL STUDY

Life-threatening ventricular arrhythmias due to transient or correctable causes: high risk for death in follow-up

D. George Wyse, MD, PhD, FACC*,*, Peter L. Friedman, MD, FACC{dagger}, Michael A. Brodsky, MD, FACC{ddagger}, Karen J. Beckman, MD, FACC§, Mark D. Carlson, MD, FACC||, Anne B. Curtis, MD, FACC, Alfred P. Hallstrom, PhD#, Merritt H. Raitt, MD, FACC**, Bruce L. Wilkoff, MD, FACC{dagger}{dagger}, H. Leon Greene, MD, FACC# for the AVID Investigators

* Cardiology Division, University of Calgary, Calgary, Alberta, Canada
{dagger} Cardiovascular Division, Brigham and Women’s Hospital, Boston, Massachusetts, USA
{ddagger} Cardiology Division, University of California at Irvine, Irvine, California, USA
§ Cardiovascular Section, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
|| Cardiology Division, Case Western Reserve University, Cleveland, Ohio, USA
Cardiovascular Division, University of Florida, Gainesville, Florida, USA
# Department of Biostatistics, University of Washington, Seattle, Washington, USA
** Division of Cardiology, Oregon Health Sciences University, Portland, Oregon, USA
{dagger}{dagger} Cardiology Division, the Cleveland Clinic Foundation, Cleveland, Ohio, USA

Manuscript received February 7, 2001; revised manuscript received May 29, 2001, accepted August 8, 2001.

* Correspondence: Dr. D. George Wyse, University of Calgary, 3330 Hospital Drive, Northwest, Calgary, Alberta, T2N 4N1 Canada. Reprint requests: AVID Clinical Trial Center, 1107 NE 45th Street, Suite 505, Seattle, Washington 98105 USA
dgwyse{at}ucalgary.ca

OBJECTIVES

This study evaluated the prognosis of patients resuscitated from ventricular tachycardia (VT) or ventricular fibrillation (VF) with a transient or correctable cause suspected as the cause of the VT/VF.

BACKGROUND

Patients resuscitated from VT/VF in whom a transient or correctable cause has been identified are thought to be at low risk for recurrence and often receive no primary treatment for their arrhythmias.

METHODS

In the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial, patients with a potentially transient or correctable cause of VT/VF were not eligible for randomization. The mortality of these patients was compared with the mortality of patients with a known high risk of recurrence of VT/VF in the AVID registry.

RESULTS

Compared with patients having high risk VT/VF, those with a transient or correctable cause for their presenting VT/VF were younger and had a higher left ventricular ejection fraction. These patients were more often treated with revascularization as the primary therapy, more commonly received a beta-blocker, less often required therapy for congestive heart failure and less commonly received either an antiarrhythmic drug or an implantable cardioverter defibrillator. Nevertheless, subsequent mortality of patients with a transient or correctable cause of VT/VF was no different or perhaps even worse than that of the primary VT/VF population.

CONCLUSIONS

Patients identified with a transient or correctable cause for their VT/VF remain at high risk for death. Further research is needed to define truly reversible causes of VT/VF. Meanwhile, these patients may require more aggressive evaluation, treatment and follow-up than is currently practiced.

Abbreviations and Acronyms
  AVID = Antiarrhythmics Versus Implantable Defibrillators trial
  CAD = coronary artery disease
  CHF = congestive heart failure
  MI = myocardial infarction
  NDIS = National Death Index Service
  VF = ventricular fibrillation
  VT = ventricular tachycardia




This article has been cited by other articles:


Home page
 JAMAHome page
L. H. Curtis, S. M. Al-Khatib, A. M. Shea, B. G. Hammill, A. F. Hernandez, and K. A. Schulman
Sex Differences in the Use of Implantable Cardioverter-Defibrillators for Primary and Secondary Prevention of Sudden Cardiac Death
JAMA, October 3, 2007; 298(13): 1517 - 1524.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
R. Passman and A. Kadish
Sudden Death Prevention With Implantable Devices
Circulation, July 31, 2007; 116(5): 561 - 571.
[Full Text] [PDF]

Home page
 CirculationHome page
L. R.C. Dekker, C. R. Bezzina, J. P.S. Henriques, M. W. Tanck, K. T. Koch, M. W. Alings, A. E.R. Arnold, M.-J. de Boer, A. P.M. Gorgels, H. R. Michels, et al.
Familial Sudden Death Is an Important Risk Factor for Primary Ventricular Fibrillation: A Case-Control Study in Acute Myocardial Infarction Patients
Circulation, September 12, 2006; 114(11): 1140 - 1145.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
Developed in Collaboration With the European Heart, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death--Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death)
J. Am. Coll. Cardiol., September 5, 2006; 48(5): 1064 - 1108.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
Developed in Collaboration With the European Heart, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death)
J. Am. Coll. Cardiol., September 5, 2006; 48(5): e247 - e346.
[Full Text] [PDF]

Home page
 Eur Heart JHome page
D. P. Zipes, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death--executive summary: A report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society.
Eur. Heart J., September 1, 2006; 27(17): 2099 - 2140.
[Full Text] [PDF]

Home page
 EuropaceHome page
Writing Committee Members, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: A report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society
Europace, September 1, 2006; 8(9): 746 - 837.
[Full Text] [PDF]

Home page
 CMAJHome page
R. Parkash, A. Tang, G. Wells, J. Blackburn, I. Stiell, C. Simpson, P. Dorian, R. Yee, D. Cameron, S. Connolly, et al.
Use of implantable cardioverter defibrillators after out-of-hospital cardiac arrest: a prospective follow-up study
Can. Med. Assoc. J., October 26, 2004; 171(9): 1053 - 1056.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
A. P. van Alem, M. G.W. Dijkgraaf, J. G.P. Tijssen, and R. W. Koster
Health System Costs of Out-of-Hospital Cardiac Arrest in Relation to Time to Shock
Circulation, October 5, 2004; 110(14): 1967 - 1973.
[Abstract] [Full Text] [PDF]

Home page
 EuropaceHome page
B. Sterk, A.P. van Alem, R. Tukkie, T.A. Simmers, and R.W. Koster
ICD-implantation guidelines versus clinical practice: a prospective study of out-of-hospital cardiac arrest survivors
Europace, January 1, 2004; 6(3): 179 - 183.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
J. P. DiMarco
Implantable Cardioverter-Defibrillators
N. Engl. J. Med., November 6, 2003; 349(19): 1836 - 1847.
[Full Text] [PDF]

Home page
 ANN INTERN MEDHome page
A. E. Buxton
The Clinical Use of Implantable Cardioverter Defibrillators: Where Are We Now? Where Should We Go?
Ann Intern Med, March 18, 2003; 138(6): 512 - 514.
[Full Text] [PDF]

Home page
 Journal Watch CardiologyHome page
Think Twice Before Attributing Life-Threatening Arrhythmias to Transient or Correctable Causes
Journal Watch Cardiology, January 11, 2002; 2002(111): 6 - 6.
[Full Text]

Home page
 J Am Coll CardiolHome page
S. Viskin, A. Halkin, and J. E. Olgin
Treatable causes of sudden death: not really "treatable" or not really the cause?
J. Am. Coll. Cardiol., November 15, 2001; 38(6): 1725 - 1727.
[Full Text] [PDF]


HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
Copyright © 2001 by the American College of Cardiology Foundation.