CLINICAL STUDIES
Double-oblique free-breathing high resolution three-dimensional coronary magnetic resonance angiography
Matthias Stuber, PhD*  ,
René M. Botnar, PhD* ,
Peter G. Danias, MD, PhD*,
Daniel K. Sodickson, MD, PhD*,
Kraig V. Kissinger, RT, MS*,
Marc Van Cauteren, PhD ,
Jan De Becker, PhD and
Warren J. Manning, MD* 
* Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Philips Medical Systems, Best, The Netherlands
Philips Medical Systems, Tokyo, Japan
Manuscript received November 28, 1998;
revised manuscript received March 19, 1999,
accepted April 23, 1999.
Reprint requests and correspondence: Dr. Matthias Stuber, Beth Israel Deaconess Medical Center, Cardiovascular Division, 330 Brookline Ave., Boston, Massachusetts 02215
mstuber{at}caregroup.harvard.edu
OBJECTIVES
The goal of the present study was to develop a strategy for three-dimensional (3D) volume acquisition along the major axes of the coronary arteries.
BACKGROUND
For high-resolution 3D free-breathing coronary magnetic resonance angiography (MRA), coverage of the coronary artery tree may be limited due to excessive measurement times associated with large volume acquisitions. Planning the 3D volume along the major axis of the coronary vessels may help to overcome such limitations.
METHODS
Fifteen healthy adult volunteers and seven patients with X-ray angiographically confirmed coronary artery disease underwent free-breathing navigator-gated and corrected 3D coronary MRA. For an accurate volume targeting of the high resolution scans, a three-point planscan software tool was applied.
RESULTS
The average length of contiguously visualized left main and left anterior descending coronary artery was 81.8 ± 13.9 mm in the healthy volunteers and 76.2 ± 16.5 mm in the patients (p = NS). For the right coronary artery, a total length of 111.7 ± 27.7 mm was found in the healthy volunteers and 79.3 ± 4.6 mm in the patients (p = NS). Comparing coronary MRA and X-ray angiography, a good agreement of anatomy and pathology was found in the patients.
CONCLUSIONS
Double-oblique submillimeter free-breathing coronary MRA allows depiction of extensive parts of the native coronary arteries. The results obtained in patients suggest that the method has the potential to be applied in broader prospective multicenter studies where coronary MRA is compared with X-ray angiography.
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Abbreviations and Acronyms
| | CNR | = contrast-to-noise ratio | | ECG | = electrocardiogram/electrocardiographic | | LAD | = left anterior descending coronary artery | | LCX | = left circumflex coronary artery | | LM | = left main coronary artery | | MR | = magnetic resonance | | MRA | = magnetic resonance angiography | | RCA | = right coronary artery | | RHD | = right hemidiaphragm | | ROI | = region of interest | | SNR | = signal-to-noise ratio | | TE | = echo time | | TFE-EPI | = turbo field echo-echo planar imaging | | TR | = repetition time | | 2D | = two-dimensional | | 3D | = three-dimensional |
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