JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
 QUICK SEARCH:   [advanced]


     


J Am Coll Cardiol, 1998; 31:1650-1657
© 1998 by the American College of Cardiology Foundation
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Weiss, B.
Right arrow Articles by Hess, O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Weiss, B.
Right arrow Articles by Hess, O.

Outcome of pulmonary vascular disease in pregnancy: a systematic overview from 1978 through 1996

BM Weiss, L Zemp, B Seifert, and OM Hess

Department of Anesthesiology, University Hospital, Zurich, Switzerland.

OBJECTIVES: Published reports were reviewed to evaluate the characteristics of peripartal management and the late pregnancy outcome in women with pulmonary vascular disease (PVD). BACKGROUND: Pulmonary hypertension poses one of the highest risks for maternal mortality, but actual data on the maternal and neonatal prognosis in this group are lacking. METHODS: Reports published from 1978 through 1996 of Eisenmenger's syndrome (n = 73), primary pulmonary hypertension (PPH) (n = 27) and secondary vascular pulmonary hypertension (SVPH) (n = 25) complicating late pregnancy were included and analyzed using logistic regression analysis. RESULTS: Maternal mortality was 36% in Eisenmenger's syndrome, 30% in PPH and 56% (p < 0.08 vs. other two groups) in SVPH. Except for three prepartal deaths due to Eisenmenger's syndrome, all fatalities occurred within 35 days after delivery. Neonatal survival ranging from 87% to 89% was similar in the three groups. Previous pregnancies, timing of the diagnosis and hospital admission, operative delivery and diastolic pulmonary artery pressure were significant univariate (p < 0.05) maternal risk factors. Late diagnosis (p = 0.002, odds ratio 5.4) and late hospital admission (p = 0.01, odds ratio 1.1 per week of pregnancy) were independent predictive risk factors of maternal mortality. CONCLUSIONS: In the last two decades maternal mortality was comparable in patients with Eisenmenger's syndrome and PPH; however, it was relevantly higher in SVPH. Maternal prognosis depends on the early diagnosis of PVD, early hospital admission, individually tailored treatment during pregnancy and medical therapy and care focused on the postpartal period.


This article has been cited by other articles:


Home page
Obstet GynecolHome page
E. F. Chakravarty, D. Khanna, and L. Chung
Pregnancy Outcomes in Systemic Sclerosis, Primary Pulmonary Hypertension, and Sickle Cell Disease
Obstet. Gynecol., April 1, 2008; 111(4): 927 - 934.
[Abstract] [Full Text] [PDF]


Home page
Am J Health Syst PharmHome page
S. Huang and E. R. H. DeSantis
Treatment of pulmonary arterial hypertension in pregnancy
Am. J. Health Syst. Pharm., September 15, 2007; 64(18): 1922 - 1926.
[Abstract] [Full Text] [PDF]


Home page
Canadian J. AnesthesiaHome page
R. B. George, A. J. Olufolabi, and H. A. Muir
Critical arrhythmia associated with pulmonary artery catheterization in a parturient with severe pulmonary hypertension
Can J Anesth, June 1, 2007; 54(6): 486 - 487.
[Full Text] [PDF]


Home page
The Obstetrician and GynaecologistHome page
E. Gelson, M. Johnson, M. Gatzoulis, and A. Uebing
Cardiac disease in pregnancy. Part 1: congenital heart disease
Obstet Gynaecol (Lond), January 1, 2007; 9(1): 15 - 20.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
S. Thorne, A. MacGregor, and C. Nelson-Piercy
Risks of contraception and pregnancy in heart disease.
Heart, October 1, 2006; 92(10): 1520 - 1525.
[Full Text] [PDF]


Home page
CirculationHome page
V. V. McLaughlin and M. D. McGoon
Pulmonary Arterial Hypertension
Circulation, September 26, 2006; 114(13): 1417 - 1431.
[Full Text] [PDF]


Home page
Obstet GynecolHome page
D. Bendayan, M. Hod, G. Oron, A. Sagie, L. Eidelman, D. Shitrit, and M. R. Kramer
Pregnancy Outcome in Patients With Pulmonary Arterial Hypertension Receiving Prostacyclin Therapy
Obstet. Gynecol., November 1, 2005; 106(5): 1206 - 1210.
[Abstract] [Full Text] [PDF]


Home page
ANN INTERN MEDHome page
L. J. Rubin and D. B. Badesch
Evaluation and Management of the Patient with Pulmonary Arterial Hypertension
Ann Intern Med, August 16, 2005; 143(4): 282 - 292.
[Abstract] [Full Text] [PDF]


Home page
Eur Respir JHome page
C. A. Elliot, P. Stewart, V. J. Webster, G. H. Mills, S. P. Hutchinson, E. S. Howarth, F. A. Bu'Lock, R. A. Lawson, I. J. Armstrong, and D. G. Kiely
The use of iloprost in early pregnancy in patients with pulmonary arterial hypertension
Eur. Respir. J., July 1, 2005; 26(1): 168 - 173.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
A Siva and A M Shah
Moderate mitral stenosis in pregnancy: the haemodynamic impact of diuresis
Heart, January 1, 2005; 91(1): e3 - e3.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
Task Force members, N. Galie, A. Torbicki, R. Barst, P. Dartevelle, S. Haworth, T. Higenbottam, H. Olschewski, A. Peacock, G. Pietra, et al.
Guidelines on diagnosis and treatment of pulmonary arterial hypertension: The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology
Eur. Heart J., December 2, 2004; 25(24): 2243 - 2278.
[Full Text] [PDF]


Home page
Br J AnaesthHome page
P. Ray, G. J. Murphy, and L. E. Shutt
Recognition and management of maternal cardiac disease in pregnancy
Br. J. Anaesth., September 1, 2004; 93(3): 428 - 439.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
W.-R. Chou, P.-H. Kuo, J.-C. Shih, and P.-C. Yang
A 31-Year-Old Pregnant Woman With Progressive Exertional Dyspnea and Differential Cyanosis
Chest, August 1, 2004; 126(2): 638 - 641.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J. S. Child
Fallot's tetralogy and pregnancy: Prognostication and prophesy
J. Am. Coll. Cardiol., July 7, 2004; 44(1): 181 - 183.
[Full Text] [PDF]


Home page
Br J AnaesthHome page
A. T. Lovell
Anaesthetic implications of grown-up congenital heart disease
Br. J. Anaesth., July 1, 2004; 93(1): 129 - 139.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
D. B. Badesch, S. H. Abman, G. S. Ahearn, R. J. Barst, D. C. McCrory, G. Simonneau, and V. V. McLaughlin
Medical Therapy For Pulmonary Arterial Hypertension: ACCP Evidence-Based Clinical Practice Guidelines
Chest, July 1, 2004; 126(1_suppl): 35S - 62S.
[Abstract] [Full Text] [PDF]


Home page
Obstet GynecolHome page
I Bildirici and J B. Shumway
Intravenous and Inhaled Epoprostenol for Primary Pulmonary Hypertension During Pregnancy and Delivery
Obstet. Gynecol., May 1, 2004; 103(5): 1102 - 1105.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
S A Thorne
Pregnancy in heart disease
Heart, April 1, 2004; 90(4): 450 - 456.
[Full Text] [PDF]


Home page
ChestHome page
C. Geohas and V. V. McLaughlin
Successful Management of Pregnancy in a Patient With Eisenmenger Syndrome With Epoprostenol
Chest, September 1, 2003; 124(3): 1170 - 1173.
[Abstract] [Full Text] [PDF]


Home page
Eur. J. Cardiothorac. Surg.Home page
A. F. Corno, P. Tozzi, C. Y. Genton, and L. K. von Segesser
Surgically induced unilateral pulmonary hypertension: time-related analysis of a new experimental model
Eur. J. Cardiothorac. Surg., April 1, 2003; 23(4): 513 - 517.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
A. D. J. Ten Harkel, N. A. Blom, and J. Ottenkamp
Isolated Unilateral Absence of a Pulmonary Artery: A Case Report and Review of the Literature
Chest, October 1, 2002; 122(4): 1471 - 1477.
[Abstract] [Full Text] [PDF]


Home page
LupusHome page
E Mcmillan, W L Martin, J Waugh, I Rushton, M Lewis, T Clutton-Brock, J N Townend, M D Kilby, and C Gordon
Management of pregnancy in women with pulmonary hypertension secondary to SLE and anti-phospholipid syndrome
Lupus, June 1, 2002; 11(6): 392 - 398.
[Abstract] [PDF]


Home page
Obstet GynecolHome page
G. K. Lam, R. E. Stafford, J. Thorp, K. J. Moise Jr, and B. A. Cairns
Inhaled Nitric Oxide for Primary Pulmonary Hypertension in Pregnancy
Obstet. Gynecol., November 1, 2001; 98(5): 895 - 898.
[Abstract] [Full Text] [PDF]


Home page
Canadian J. AnesthesiaHome page
C. Decoene, K. Bourzoufi, D. Moreau, F. Narducci, F. Crepin, and R. Krivosic-Horber
Use of inhaled nitric oxide for emergency Cesarean section in a woman with unexpected primary pulmonary hypertension : [L'inhalation d'oxyde nitrique pour la cesarienne d'urgence associee a une hypertension pulmonaire primitive inattendue]
Can J Anesth, June 1, 2001; 48(6): 584 - 587.
[Abstract] [Full Text]


Home page
HeartHome page
S. C Siu and J. M Colman
CONGENITAL HEART DISEASE: Heart disease and pregnancy
Heart, June 1, 2001; 85(6): 710 - 715.
[Full Text]


Home page
Br J AnaesthHome page
P. J. Cole, M. H. Cross, and M. Dresner
Incremental spinal anaesthesia for elective Caesarean section in a patient with Eisenmenger's syndrome
Br. J. Anaesth., May 1, 2001; 86(5): 723 - 726.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
R. Stewart, D. Tuazon, G. Olson, and A. G. Duarte
Pregnancy and Primary Pulmonary Hypertension : Successful Outcome With Epoprostenol Therapy
Chest, March 1, 2001; 119(3): 973 - 975.
[Abstract] [Full Text] [PDF]


Home page
JRSMHome page
P S C Wong, S Constantinides, V Kanellopoulos, C R Kennedy, D Watson, and M F Shiu
Primary pulmonary hypertension in pregnancy
J R Soc Med, January 10, 2001; 94(10): 523 - 525.
[Full Text] [PDF]


Home page
NEJMHome page
M. E. Brickner, L. D. Hillis, and R. A. Lange
Congenital Heart Disease in Adults- Second of Two Parts
N. Engl. J. Med., February 3, 2000; 342(5): 334 - 342.
[Full Text] [PDF]


Home page
Eur Heart JHome page
B.M Weiss and O.M Hess
Pulmonary vascular disease and pregnancy: current controversies, management strategies, and perspectives
Eur. Heart J., January 2, 2000; 21(2): 104 - 115.
[PDF]




HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
Copyright © 1998 by the American College of Cardiology Foundation.