JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
 QUICK SEARCH:   [advanced]


     


J Am Coll Cardiol, 1998; 31:577-582
© 1998 by the American College of Cardiology Foundation
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Osada, N
Right arrow Articles by Donohue, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Osada, N
Right arrow Articles by Donohue, T.

Cardiopulmonary exercise testing identifies low risk patients with heart failure and severely impaired exercise capacity considered for heart transplantation

N Osada, BR Chaitman, LW Miller, D Yip, MB Cishek, TL Wolford, and TJ Donohue

Department of Medicine, Saint Louis University School of Medicine, Missouri, USA.

OBJECTIVES: The 3-year survival rates of 500 patients with congestive heart failure (CHF) referred for heart transplantation were assessed to evaluate the clinical and exercise variables most useful for estimating prognostic risk. BACKGROUND: Detailed prognostic risk stratification of patients with a peak exercise oxygen consumption (VO2) < or = 14 ml/min per kg to identify lower risk patient subsets has been limited in earlier series by relatively small sample size. METHODS: Cardiopulmonary exercise testing was performed in 500 patients with CHF referred for heart transplantation; 154 (31%) had a peak exercise VO2 < or = 14 ml/min per kg. Univariate and multivariate analyses were performed to identify the 3-year prognostic risk. RESULTS: The 55% 3-year survival rate of the 77 patients with a peak exercise VO2 < or = 14 ml/min per kg unable to reach a peak exercise systolic blood pressure (SBP) of 120 mm Hg was significantly lower than the 83% survival rate in the 74 patients able to reach this exercise blood pressure (p = 0.004). Multivariate analysis revealed that peak exercise SBP (p = 0.0005) and percent predicted peak VO2 < or = 50% (p = 0.04) were the two most important predictors for the combined end point of death or listing as Status 1. CONCLUSIONS: Peak exercise SBP and percent predicted peak exercise VO2 are two inexpensive and easily measured noninvasive variables that can be used to further prognostically risk stratify ambulatory patients with CHF referred for heart transplantation with a peak exercise VO2 < or = 14 ml/min per kg.


This article has been cited by other articles:


Home page
CirculationHome page
D. Mancini and T. H. LeJemtel
Is Ventilatory Classification Preferable to Peak Oxygen Consumption for Risk Stratification in Heart Failure?
Circulation, May 8, 2007; 115(18): 2376 - 2378.
[Full Text] [PDF]


Home page
ChestHome page
P. A. McCullough, M. J. Gallagher, A. T. deJong, K. R. Sandberg, J. E. Trivax, D. Alexander, G. Kasturi, S. M. A. Jafri, K. R. Krause, D. L. Chengelis, et al.
Cardiorespiratory Fitness and Short-term Complications After Bariatric Surgery.
Chest, August 1, 2006; 130(2): 517 - 525.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
S. Elmariah, L. R. Goldberg, M. T. Allen, and A. Kao
Effects of Gender on Peak Oxygen Consumption and the Timing of Cardiac Transplantation
J. Am. Coll. Cardiol., June 6, 2006; 47(11): 2237 - 2242.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
M. J. Gallagher, B. A. Franklin, J. K. Ehrman, S. J. Keteyian, C. A. Brawner, A. T. deJong, and P. A. McCullough
Comparative Impact of Morbid Obesity vs Heart Failure on Cardiorespiratory Fitness
Chest, June 1, 2005; 127(6): 2197 - 2203.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
U. Corra, A. Mezzani, E. Bosimini, and P. Giannuzzi
Cardiopulmonary Exercise Testing and Prognosis in Chronic Heart Failure*: A Prognosticating Algorithm for the Individual Patient
Chest, September 1, 2004; 126(3): 942 - 950.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart J SupplHome page
F.X Kleber, P Waurick, and M Winterhalter
CPET in heart failure
Eur. Heart J. Suppl., August 1, 2004; 6(suppl_D): D1 - D4.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
H. Rickli, W. Kiowski, M. Brehm, D. Weilenmann, C. Schalcher, A. Bernheim, E. Oechslin, and H. P. Brunner-La Rocca
Combining low-intensity and maximal exercise test results improves prognostic prediction in chronic heart failure
J. Am. Coll. Cardiol., July 2, 2003; 42(1): 116 - 122.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
A. Koike, N. Shimizu, A. Tajima, T. Aizawa, L. T. Fu, H. Watanabe, and H. Itoh
Relation Between Oscillatory Ventilation at Rest Before Cardiopulmonary Exercise Testing and Prognosis in Patients With Left Ventricular Dysfunction
Chest, February 1, 2003; 123(2): 372 - 379.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
J. G Lainchbury and A M. Richards
EXERCISE TESTING IN THE ASSESSMENT OF CHRONIC CONGESTIVE HEART FAILURE
Heart, December 1, 2002; 88(5): 538 - 543.
[Full Text] [PDF]


Home page
ChestHome page
C. Scharf, T. Merz, W. Kiowski, E. Oechslin, C. Schalcher, and H. P. Brunner-La Rocca
Noninvasive Assessment of Cardiac Pumping Capacity During Exercise Predicts Prognosis in Patients With Congestive Heart Failure
Chest, October 1, 2002; 122(4): 1333 - 1339.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
R. Wensel, C. F. Opitz, S. D. Anker, J. Winkler, G. Hoffken, F. X. Kleber, R. Sharma, M. Hummel, R. Hetzer, and R. Ewert
Assessment of Survival in Patients With Primary Pulmonary Hypertension: Importance of Cardiopulmonary Exercise Testing
Circulation, July 16, 2002; 106(3): 319 - 324.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
A. Cohen-Solal, J.Y. Tabet, D. Logeart, P. Bourgoin, M. Tokmakova, and M. Dahan
A non-invasively determined surrogate of cardiac power ('circulatory power') at peak exercise is a powerful prognostic factor in chronic heart failure
Eur. Heart J., May 2, 2002; 23(10): 806 - 814.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
A. Koike, H. Itoh, M. Kato, H. Sawada, T. Aizawa, L. T. Fu, and H. Watanabe
Prognostic Power of Ventilatory Responses During Submaximal Exercise in Patients With Chronic Heart Disease*
Chest, May 1, 2002; 121(5): 1581 - 1588.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
S.G Williams, G.A Cooke, D.J Wright, W.J Parsons, R.L Riley, P Marshall, and L-B Tan
Peak exercise cardiac power output; a direct indicator of cardiac function strongly predictive of prognosis in chronic heart failure
Eur. Heart J., August 2, 2001; 22(16): 1496 - 1503.
[Abstract] [PDF]


Home page
Ann. Thorac. Surg.Home page
C. C. Canver and J. Chanda
Heart transplantation
Ann. Thorac. Surg., August 1, 2001; 72(2): 658 - 660.
[Full Text] [PDF]


Home page
Eur Heart JHome page
Recommendations for exercise testing in chronic heart faliure patients
Eur. Heart J., January 1, 2001; 22(1): 37 - 45.
[PDF]


Home page
J Am Coll CardiolHome page
A. F. Osman, M. R. Mehra, C. J. Lavie, E. Nunez, and R. V. Milani
The incremental prognostic importance of body fat adjusted peak oxygen consumption in chronic heart failure
J. Am. Coll. Cardiol., December 1, 2000; 36(7): 2126 - 2131.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
C Zugck, C Kruger, S Durr, S.H Gerber, A Haunstetter, K Hornig, W Kubler, and M Haass
Is the 6-minute walk test a reliable substitute for peak oxygen uptake in patients with dilated cardiomyopathy?
Eur. Heart J., April 1, 2000; 21(7): 540 - 549.
[Abstract] [PDF]


Home page
CirculationHome page
D. Mancini, T. LeJemtel, and K. Aaronson
Peak VO2 : A Simple yet Enduring Standard
Circulation, March 14, 2000; 101(10): 1080 - 1082.
[Full Text] [PDF]


Home page
HeartHome page
G P Armstrong, S G Carlier, K Fukamachi, J D Thomas, and T H Marwick
Estimation of cardiac reserve by peak power: validation and initial application of a simplified index
Heart, September 1, 1999; 82(3): 357 - 364.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
M. Metra, P. Faggiano, A. D'Aloia, S. Nodari, A. Gualeni, D. Raccagni, and L. Dei Cas
Use of cardiopulmonary exercise testing with hemodynamic monitoring in the prognostic assessment of ambulatory patients with chronic heart failure
J. Am. Coll. Cardiol., March 15, 1999; 33(4): 943 - 950.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
A. Cohen-Solal, Y. Esanu, D. Logeart, F. Pessione, C. Dubois, G. Dreyfus, R. Gourgon, and P. Merlet
Cardiac metaiodobenzylguanidine uptake in patients with moderate chronic heart failure: relationship with peak oxygen uptake and prognosis
J. Am. Coll. Cardiol., March 1, 1999; 33(3): 759 - 766.
[Abstract] [Full Text] [PDF]




HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
Copyright © 1998 by the American College of Cardiology Foundation.