JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
 QUICK SEARCH:   [advanced]


     


J Am Coll Cardiol, 1997; 30:1417-1419
© 1997 by the American College of Cardiology Foundation
This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lindenfeld, J
Right arrow Articles by Salerno, J
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lindenfeld, J
Right arrow Articles by Salerno, J

Where are all the women with heart failure?

J Lindenfeld, H Krause-Steinrauf, and J Salerno

In recent clinical trials of medical therapy for heart failure, only approximately 20% of patients enrolled were women. The reasons for the low enrollment of women have not been clear. Although the incidence of heart failure is higher in men than in women, the prevalence is equal. When men and women with heart failure and a low left ventricular ejection fraction are compared, the women are more symptomatic and have a similarly poor outcome. Because mortality is worse in men than in women in large populations of patients with heart failure, there may be important pathophysiologic differences. Substantial data suggest that women may have diastolic dysfunction more often than men. This difference would explain differences in mortality and the difficulty in enrolling women in studies of medical therapy for heart failure with underlying systolic dysfunction.


This article has been cited by other articles:


Home page
CirculationHome page
J. P. Konhilas and L. A. Leinwand
The Effects of Biological Sex and Diet on the Development of Heart Failure
Circulation, December 4, 2007; 116(23): 2747 - 2759.
[Full Text] [PDF]


Home page
CirculationHome page
E. O'Meara, T. Clayton, M. B. McEntegart, J. J.V. McMurray, I. L. Pina, C. B. Granger, J. Ostergren, E. L. Michelson, S. D. Solomon, S. Pocock, et al.
Sex Differences in Clinical Characteristics and Prognosis in a Broad Spectrum of Patients With Heart Failure: Results of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) Program
Circulation, June 19, 2007; 115(24): 3111 - 3120.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
A. L. Taylor, J. Lindenfeld, S. Ziesche, M. N. Walsh, J. E. Mitchell, K. Adams, S. W. Tam, E. Ofili, M. L. Sabolinski, M. Worcel, et al.
Outcomes by Gender in the African-American Heart Failure Trial
J. Am. Coll. Cardiol., December 5, 2006; 48(11): 2263 - 2267.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J. K. Ghali, H. J. Krause-Steinrauf, K. F. Adams Jr, S. S. Khan, Y. D. Rosenberg, C. W. Yancy Jr, J. B. Young, S. Goldman, M. A. Peberdy, and J. Lindenfeld
Gender differences in advanced heart failure: insights from the BEST study
J. Am. Coll. Cardiol., December 17, 2003; 42(12): 2128 - 2134.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
M. Martinez-Selles, J. A.G. Robles, L. Prieto, M. D. Munoa, E. Frades, O. Diaz-Castro, and J. Almendral
Systolic dysfunction is a predictor of long term mortality in men but not in women with heart failure
Eur. Heart J., November 2, 2003; 24(22): 2046 - 2053.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J. Lindenfeld, J. K. Ghali, H. J. Krause-Steinrauf, S. Khan, K. Adams Jr, S. Goldman, M. A. Peberdy, C. Yancy, S. Thaneemit-Chen, R. L. Larsen, et al.
Hormone replacement therapy is associated with improved survival in women with advanced heart failure
J. Am. Coll. Cardiol., October 1, 2003; 42(7): 1238 - 1245.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
F. A. Masoudi, E. P. Havranek, G. Smith, R. H. Fish, J. F. Steiner, D. L. Ordin, and H. M. Krumholz
Gender, age, and heart failure with preserved left ventricular systolic function
J. Am. Coll. Cardiol., January 15, 2003; 41(2): 217 - 223.
[Abstract] [Full Text] [PDF]


Home page
NEJMHome page
S. S. Rathore, Y. Wang, and H. M. Krumholz
Sex-Based Differences in the Effect of Digoxin for the Treatment of Heart Failure
N. Engl. J. Med., October 31, 2002; 347(18): 1403 - 1411.
[Abstract] [Full Text] [PDF]


Home page
Am J Crit CareHome page
M. S. Riedinger, K. A. Dracup, M.-L. Brecht, and for the SOLVD Investigators
Quality of Life in Women With Heart Failure, Normative Groups, and Patients With Other Chronic Conditions
Am. J. Crit. Care., May 1, 2002; 11(3): 211 - 219.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
M. Gomberg-Maitland, D. A. Baran, and V. Fuster
Treatment of Congestive Heart Failure: Guidelines for the Primary Care Physician and the Heart Failure Specialist
Arch Intern Med, February 12, 2001; 161(3): 342 - 352.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
C. S Hayward, W. V Kalnins, and R. P Kelly
Gender-related differences in left ventricular chamber function
Cardiovasc Res, February 1, 2001; 49(2): 340 - 350.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
A Cohen-Solal, M Desnos, F Delahaye, J.P Emeriau, and G Hanania
A national survey of heart failure in French hospitals
Eur. Heart J., May 1, 2000; 21(9): 763 - 769.
[Abstract] [PDF]


Home page
Cardiovasc ResHome page
C. S. Hayward, R. P. Kelly, and P. Collins
The roles of gender, the menopause and hormone replacement on cardiovascular function
Cardiovasc Res, April 1, 2000; 46(1): 28 - 49.
[Full Text] [PDF]


Home page
Arch Intern MedHome page
G. Gambassi, K. L. Lapane, A. Sgadari, P. Carbonin, C. Gatsonis, L. A. Lipsitz, V. Mor, R. Bernabei, and for the SAGE Study Group
Effects of Angiotensin-Converting Enzyme Inhibitors and Digoxin on Health Outcomes of Very Old Patients With Heart Failure
Arch Intern Med, January 10, 2000; 160(1): 53 - 60.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
B.A. Bart, G. Ertl, P. Held, J. Kuch, A.P. Maggioni, J. McMurray, E.L. Michelson, J.L. Rouleau, L. Warner Stevenson, K. Swedberg, et al.
Contemporary management of patients with left ventricular systolic dysfunction. Results from the Study of Patients Intolerant of Converting Enzyme Inhibitors (SPICE) Registry
Eur. Heart J., August 2, 1999; 20(16): 1182 - 1190.
[Abstract] [PDF]




HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
Copyright © 1997 by the American College of Cardiology Foundation.