|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
|
|
|
|||||||||
|
|||||||||||
|
J Am Coll Cardiol, 1995; 25:1282-1285 © 1995 by the American College of Cardiology Foundation |
First Department of Internal Medicine, National Defense Medical College, Saitama, Japan.
OBJECTIVES. The purpose of this study was to determine the prevalence of intracoronary thrombus and associated anatomic abnormalities in patients with postinfarction angina using coronary angioscopy and angiography. BACKGROUND. Postinfarction angina, previously studied by angiographic methods only, identifies patients at high risk for sudden death, recurrent angina and refractory angina. The recent development of coronary angioscopy, which permits direct observation of a thrombus or atheroma and is especially used for the detection of intraluminal changes, encourages a reexamination of the pathogenesis of postinfarction angina. METHODS. Fifty-one consecutive patients with a diagnosis of acute myocardial infarction underwent cardiac catheterization. Coronary angiography followed immediately by coronary angioscopy was performed in 17 patients with and 34 without postinfarction angina during the same period of time (10.2 +/- 3.7 or 15.7 +/- 5.5 days [mean +/- SD]) after the onset of acute myocardial infarction. RESULTS. The frequency of thrombus, as observed by angioscopy, was significantly higher in patients with than without postinfarction angina (17 of 17 vs. 5 of 34, respectively, p < 0.01). There were no significant differences between groups with respect to degree of stenosis in the infarct-related artery, number of vessels with significant stenosis, presence of collateral flow, type of therapy and risk factors. CONCLUSIONS. Infarct-related artery thrombus is universally present in postinfarction angina and may be the primary pathogenic factor. Angioscopy is much more sensitive than coronary angiography for the detection of coronary thrombus.
This article has been cited by other articles:
|
|
 |
|
  A. Rodriguez-Sinovas, J. Bis, I. Anivarro, J. de la Torre, A. Bayes-Genis, and J. Cinca Coronary smooth muscle reactivity to muscarinic stimulation after ischemia-reperfusion in porcine myocardial infarction J Appl Physiol, July 1, 2003; 95(1): 81 - 88. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Ueda, M. Asakura, O. Yamaguchi, A. Hirayama, M. Hori, and K. Kodama The healing process of infarct-related plaques: Insights from 18 months of serial angioscopic follow-up J. Am. Coll. Cardiol., December 1, 2001; 38(7): 1916 - 1922. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. W. Smalling and H. V. Anderson Pathophysiological Insight Into the Possible Optimal Therapies for Acute Myocardial Infarction and Unstable Angina Circulation, January 13, 1998; 97(1): 10 - 11. [Full Text] [PDF]
|
|
|
|
|
|
E. Van Belle, J.-M. Lablanche, C. Bauters, N. Renaud, E. P. McFadden, and M. E. Bertrand Coronary Angioscopic Findings in the Infarct-Related Vessel Within 1 Month of Acute Myocardial Infarction : Natural History and the Effect of Thrombolysis Circulation, January 13, 1998; 97(1): 26 - 33. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. G. Lehmann, R. J. van Suylen, J. Stibbe, C. J. Slager, J. A. Oomen, A. Maas, C. di Mario, P. deFeyter, and P. W. Serruys Composition of Human Thrombus Assessed by Quantitative Colorimetric Angioscopic Analysis Circulation, November 4, 1997; 96(9): 3030 - 3041. [Abstract] [Full Text]
|
|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
