|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
|
|
|
|||||||||
|
|||||||||||
|
J Am Coll Cardiol, 1994; 24:74-80 © 1994 by the American College of Cardiology Foundation |
Department of Cardiology, Cleveland Clinic Foundation, Ohio.
OBJECTIVES. We attempted to develop a statistical model to facilitate risk stratification for long-term outcome after elective coronary angioplasty. BACKGROUND. Our understanding of factors related to long-term outcome after coronary angioplasty is limited. Adequate assessment of risk indexes could potentially lead to more appropriate use of percutaneous revascularization. METHODS. We studied 5,000 consecutive patients and assessed 19 clinical and anatomic variables as predictors of long-term event-free survival. Events were defined as death of any cause, myocardial infarction, bypass surgery or repeat percutaneous transluminal coronary angioplasty. Cox proportional hazards models were used to develop an equation for predicting event-free survival in a subset of 4,000 patients. The equation was validated with the remaining 1,000 patients. Variables that were significantly associated with an adverse outcome in the multivariate model included age > 60 years, extent of disease, Canadian Cardiovascular Society functional class, previous coronary angioplasty, male gender, history of diabetes mellitus, history of hypertension and history of congestive heart failure. RESULTS. The statistical model was used to develop a simplified scoring system, and the patients were assigned to three risk subgroups. Event-free survival curves for the three groups were significantly different (p = 0.0001). High risk patients had worse outcomes for each of the end points compared with low and moderate risk patients (p < 0.02). CONCLUSIONS. We demonstrated that clinical and anatomic variables can be used to risk-stratify long-term outcome after angioplasty, that a simplified scoring system can be used for risk stratification and that high risk patients have a low event-free survival.
This article has been cited by other articles:
|
|
 |
|
  S J Hong, M H Kim, T H Ahn, Y K Ahn, J H Bae, W J Shim, Y M Ro, and D-S Lim Multiple predictors of coronary restenosis after drug-eluting stent implantation in patients with diabetes Heart, August 1, 2006; 92(8): 1119 - 1124. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Sharma and S. J Brecker Dobutamine stress echocardiography in diabetes The British Journal of Diabetes & Vascular Disease, January 1, 2005; 5(1): 42 - 46. [Abstract] [PDF]
|
|
|
|
 |
|
 M. A. Qureshi, R. D. Safian, C. L. Grines, J. A. Goldstein, D. C. Westveer, S. Glazier, M. Balasubramanian, and W. W. O'Neill Simplified scoring system for predicting mortality after percutaneous coronary intervention J. Am. Coll. Cardiol., December 3, 2003; 42(11): 1890 - 1895. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Singh, C. S. Rihal, F. Selzer, K. E. Kip, K. Detre, and D. R. Holmes Jr Validation of Mayo clinic risk adjustment model for in-hospital complications after percutaneous coronary interventions, using the National Heart, Lung, and Blood Institute dynamic registry J. Am. Coll. Cardiol., November 19, 2003; 42(10): 1722 - 1728. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P M Schofield Indications for percutaneous and surgical revascularisation: how far does the evidence base guide us? Heart, May 1, 2003; 89(5): 565 - 570. [Full Text] [PDF]
|
|
|
|
 |
|
 A. Heiat, C. P. Gross, and H. M. Krumholz Representation of the Elderly, Women, and Minorities in Heart Failure Clinical Trials Arch Intern Med, August 12, 2002; 162(15): 1682 - 1688. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. H. Marwick, C. Case, S. Sawada, C. Vasey, L. Short, and M. Lauer Use of Stress Echocardiography to Predict Mortality in Patients With Diabetes and Known or Suspected Coronary Artery Disease Diabetes Care, June 1, 2002; 25(6): 1042 - 1048. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. T. O'Connor, D. J. Malenka, H. Quinton, J. F. Robb, M. A. Kellett Jr., S. Shubrooks, W. A. Bradley, M. J. Hearne, M. W. Watkins, D. E. Wennberg, et al. Multivariate prediction of in-hospital mortality after percutaneous coronary interventions in 1994-1996 J. Am. Coll. Cardiol., September 1, 1999; 34(3): 681 - 691. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Aristides, M. Gliksman, N. Rajan, and P. Davey Effectiveness and cost-effectiveness of single bolus treatment with abciximab (Reo Pro) in preventing restenosis following percutaneous transluminal coronary angioplasty in high risk patients Heart, January 1, 1998; 79(1): 12 - 17. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. E. Kip, D. P. Faxon, K. M. Detre, W. Yeh, S. F. Kelsey, and J. W. Currier Coronary Angioplasty in Diabetic Patients: The National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry Circulation, October 15, 1996; 94(8): 1818 - 1825. [Abstract] [Full Text]
|
|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
