|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
|
|
|
|||||||||
|
|||||||||||
|
J Am Coll Cardiol, 1994; 23:358-363 © 1994 by the American College of Cardiology Foundation |
Department of Pathophysiology, Katholieke Universiteit Leuven, Belgium.
OBJECTIVES. The aim of this study was to investigate the prognostic significance of peak oxygen uptake in patients with coronary artery disease who had an exercise test that could be sustained to exhaustion without limiting symptoms. BACKGROUND. Many studies have reported an inverse association between the level of exercise reached during a stress test and mortality or cardiovascular morbidity. These studies have used submaximal or symptom-limited exercise testing in patients with a recent myocardial infarction. METHODS. Peak oxygen uptake was measured in male patients > or = 4 weeks after myocardial infarction (312 patients) or coronary artery surgery (215 patients) by use of a graded uninterrupted exercise test performed to exhaustion. Apart from peak oxygen uptake, several risk factors for cardiovascular disease, patient and exercise characteristics and drug treatment were considered in the Cox proportional hazards model. RESULTS. During the total follow-up period of 3,213 patient-years, 53 patients died. Of these 53 patients, 33 died of cardiovascular causes. All-cause and cardiovascular mortality decreased with increasing peak oxygen uptake, even after adjustment for significant covariates. The relative hazard rates of 0.43 and 0.29 indicate that a hypothetic increase in peak oxygen uptake by 1 liter/min could be associated with decreases in all-cause and cardiovascular mortality of 57% and 71%, respectively. CONCLUSIONS. Exercise capacity is an independent predictor for subsequent all-cause and cardiovascular mortality in patients able to perform an exercise test until exhaustion.
This article has been cited by other articles:
|
|
 |
|
  M. A. Williams, W. L. Haskell, P. A. Ades, E. A. Amsterdam, V. Bittner, B. A. Franklin, M. Gulanick, S. T. Laing, and K. J. Stewart Resistance Exercise in Individuals With and Without Cardiovascular Disease: 2007 Update: A Scientific Statement From the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism Circulation, July 31, 2007; 116(5): 572 - 584. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J A Laukkanen, S Kurl, J T Salonen, T A Lakka, and R Rauramaa Peak oxygen pulse during exercise as a predictor for coronary heart disease and all cause death Heart, September 1, 2006; 92(9): 1219 - 1224. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. A. Ades, P. D. Savage, C. A. Brawner, C. E. Lyon, J. K. Ehrman, J. Y. Bunn, and S. J. Keteyian Aerobic Capacity in Patients Entering Cardiac Rehabilitation Circulation, June 13, 2006; 113(23): 2706 - 2712. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Barker, N. Artis, L.-B. Tan, A. deJong, B. A. Franklin, and P. A. McCullough Correcting data for body size may confound results. Chest, February 1, 2006; 129(2): 493 - 494. [Full Text] [PDF]
|
|
|
|
|
|
A Hager and J Hess Comparison of health related quality of life with cardiopulmonary exercise testing in adolescents and adults with congenital heart disease Heart, April 1, 2005; 91(4): 517 - 520. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R R T Castro, G Porphirio, S M Serra, and A C L Nobrega Cholinergic stimulation with pyridostigmine protects against exercise induced myocardial ischaemia Heart, October 1, 2004; 90(10): 1119 - 1123. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Laukkanen, S. Kurl, R. Salonen, R. Rauramaa, and J. T. Salonen The predictive value of cardiorespiratory fitness for cardiovascular events in men with various risk profiles: a prospective population-based cohort study Eur. Heart J., August 2, 2004; 25(16): 1428 - 1437. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Kavanagh, D. J. Mertens, L. F. Hamm, J. Beyene, J. Kennedy, P. Corey, and R. J. Shephard Peak oxygen intake and cardiac mortality in women referred for cardiac rehabilitation J. Am. Coll. Cardiol., December 17, 2003; 42(12): 2139 - 2143. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. J. Quell, J. P. Porcari, B. A. Franklin, C. Foster, R. A. Andreuzzi, and R. M. Anthony Is Brisk Walking an Adequate Aerobic Training Stimulus for Cardiac Patients? Chest, November 1, 2002; 122(5): 1852 - 1856. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kavanagh, D. J. Mertens, L. F. Hamm, J. Beyene, J. Kennedy, P. Corey, and R. J. Shephard Prediction of Long-Term Prognosis in 12 169 Men Referred for Cardiac Rehabilitation Circulation, August 6, 2002; 106(6): 666 - 671. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Franklin, K. Bonzheim, J. Warren, S. Haapaniemi, N. Byl, and N. Gordon Effects of a Contemporary, Exercise-Based Rehabilitation and Cardiovascular Risk-Reduction Program on Coronary Patients With Abnormal Baseline Risk Factors* Chest, July 1, 2002; 122(1): 338 - 343. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Thompson, S. Jabbour, R. J. Goldberg, R. Y. S. McClean, B. Z. Bilchik, C. M. Blatt, S. Ravid, and T. B. Graboys Exercise performance-based outcomes of medically treated patients with coronary artery disease and profound ST segment depression J. Am. Coll. Cardiol., December 1, 2000; 36(7): 2140 - 2145. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Reybrouck Gas Exchange Kinetics in Patients With Cardiovascular Disease Chest, August 1, 2000; 118(2): 285 - 286. [Full Text] [PDF]
|
|
|
|
|
|
M. Schwaiblmair, W. v. Scheidt, P. Uberfuhr, B. Reichart, and C. Vogelmeier Lung Function and Cardiopulmonary Exercise Performance After Heart Transplantation: Influence of Cardiac Allograft Vasculopathy Chest, August 1, 1999; 116(2): 332 - 339. [Abstract] [Full Text] [PDF]
|
|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
