JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
 QUICK SEARCH:   [advanced]


     


J Am Coll Cardiol, 1992; 20:1391-1396
© 1992 by the American College of Cardiology Foundation
This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Brugada, P
Right arrow Articles by Brugada, J
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Brugada, P
Right arrow Articles by Brugada, J

Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report

P Brugada and J Brugada

Cardiovascular Center, OLV Hospital, Aalst, Belgium.

OBJECTIVES. The objectives of this study were to present data on eight patients with recurrent episodes of aborted sudden death unexplainable by currently known diseases whose common clinical and electrocardiographic (ECG) features define them as having a distinct syndrome different from idiopathic ventricular fibrillation. BACKGROUND. Among patients with ventricular arrhythmias who have no structural heart disease, several subgroups have been defined. The present patients constitute an additional subgroup with these findings. METHODS. The study group consisted of eight patients, six male and two female, with recurrent episodes of aborted sudden death. Clinical and laboratory data and results of electrocardiography, electrophysiology, echocardiography, angiography, histologic study and exercise testing were available in most cases. RESULTS. The ECG during sinus rhythm showed right bundle branch block, normal QT interval and persistent ST segment elevation in precordial leads V1 to V2-V3 not explainable by electrolyte disturbances, ischemia or structural heart disease. No histologic abnormalities were found in the four patients in whom ventricular biopsies were performed. The arrhythmia leading to (aborted) sudden death was a rapid polymorphic ventricular tachycardia initiating after a short coupled ventricular extrasystole. A similar arrhythmia was initiated by two to three ventricular extrastimuli in four of the seven patients studied by programmed electrical stimulation. Four patients had a prolonged HV interval during sinus rhythm. One patient receiving amiodarone died suddenly during implantation of a demand ventricular pacemaker. The arrhythmia of two patients was controlled with a beta-adrenergic blocking agent. Four patients received an implantable defibrillator that was subsequently used by one of them, and all four are alive. The remaining patient received a demand ventricular pacemaker and his arrhythmia is controlled with amiodarone and diphenylhydantoin. CONCLUSIONS. Common clinical and ECG features define a distinct syndrome in this group of patients. Its causes remain unknown.


This article has been cited by other articles:


Home page
Circ. Res.Home page
H. M. Barajas-Martinez, D. Hu, J. M. Cordeiro, Y. Wu, R. J. Kovacs, H. Meltser, H. Kui, B. Elena, R. Brugada, C. Antzelevitch, et al.
Lidocaine-Induced Brugada Syndrome Phenotype Linked to a Novel Double Mutation in the Cardiac Sodium Channel
Circ. Res., August 15, 2008; 103(4): 396 - 404.
[Abstract] [Full Text] [PDF]


Home page
Circ Arrhythmia ElectrophysiolHome page
E. Delpon, J. M. Cordeiro, L. Nunez, P. E. B. Thomsen, A. Guerchicoff, G. D. Pollevick, Y. Wu, J. K. Kanters, C. T. Larsen, E. Burashnikov, et al.
Functional Effects of KCNE3 Mutation and Its Role in the Development of Brugada Syndrome
Circ Arrhythmia Electrophysiol, August 1, 2008; 1(3): 209 - 218.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
M. A. Babaee Bigi, A. Aslani, and A. Aslani
Significance of cardiac autonomic neuropathy in risk stratification of Brugada syndrome
Europace, July 1, 2008; 10(7): 821 - 824.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
D. Erkapic, T. Neumann, J. Schmitt, J. Sperzel, A. Berkowitsch, M. Kuniss, C. W. Hamm, and H.-F. Pitschner
Electrical storm in a patient with arrhythmogenic right ventricular cardiomyopathy and SCN5A mutation
Europace, July 1, 2008; 10(7): 884 - 887.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
T. Wichter
What role for autonomic dysfunction in Brugada Syndrome? Pathophysiological and prognostic implications
Europace, July 1, 2008; 10(7): 782 - 783.
[Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
M. Bebarova, T. O'Hara, J. L. M. C. Geelen, R. J. Jongbloed, C. Timmermans, Y. H. Arens, L.-M. Rodriguez, Y. Rudy, and P. G. A. Volders
Subepicardial phase 0 block and discontinuous transmural conduction underlie right precordial ST-segment elevation by a SCN5A loss-of-function mutation
Am J Physiol Heart Circ Physiol, July 1, 2008; 295(1): H48 - H58.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
A. E. Epstein, J. P. DiMarco, K. A. Ellenbogen, N.A. M. Estes III, R. A. Freedman, L. S. Gettes, A. M. Gillinov, G. Gregoratos, S. C. Hammill, D. L. Hayes, et al.
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) Developed in Collaboration With the American Association for Thoracic Surgery and Society of Thoracic Surgeons
J. Am. Coll. Cardiol., May 27, 2008; 51(21): e1 - e62.
[Full Text] [PDF]


Home page
CirculationHome page
A. E. Epstein, J. P. DiMarco, K. A. Ellenbogen, N.A. M. Estes III, R. A. Freedman, L. S. Gettes, A. M. Gillinov, G. Gregoratos, S. C. Hammill, D. L. Hayes, et al.
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): Developed in Collaboration With the American Association for Thoracic Surgery and Society of Thoracic Surgeons
Circulation, May 27, 2008; 117(21): e350 - e408.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
Y. Aizawa, M. Chinushi, M. Tagawa, H. Furushima, S. Okada, K. Iijima, D. Izumi, H. Watanabe, and S. Komura
A Post-QRS Potential in Brugada Syndrome: Its Relation to Electrocardiographic Pattern and Possible Genesis
J. Am. Coll. Cardiol., April 29, 2008; 51(17): 1720 - 1721.
[Full Text] [PDF]


Home page
CirculationHome page
M. J. Junttila, M. Gonzalez, E. Lizotte, B. Benito, K. Vernooy, A. Sarkozy, H. V. Huikuri, P. Brugada, J. Brugada, and R. Brugada
Induced Brugada-Type Electrocardiogram, a Sign for Imminent Malignant Arrhythmias
Circulation, April 8, 2008; 117(14): 1890 - 1893.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J. Francis and C. Antzelevitch
Atrial Fibrillation and Brugada Syndrome
J. Am. Coll. Cardiol., March 25, 2008; 51(12): 1149 - 1153.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
S. Nagase, K. F. Kusano, H. Morita, N. Nishii, K. Banba, A. Watanabe, S. Hiramatsu, K. Nakamura, S. Sakuragi, and T. Ohe
Longer Repolarization in the Epicardium at the Right Ventricular Outflow Tract Causes Type 1 Electrocardiogram in Patients With Brugada Syndrome
J. Am. Coll. Cardiol., March 25, 2008; 51(12): 1154 - 1161.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
M. Hayashi, S. Takatsuki, P. Maison-Blanche, A. Messali, A. Haggui, P. Milliez, A. Leenhardt, and F. Extramiana
Ventricular Repolarization Restitution Properties in Patients Exhibiting Type 1 Brugada Electrocardiogram With and Without Inducible Ventricular Fibrillation
J. Am. Coll. Cardiol., March 25, 2008; 51(12): 1162 - 1168.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
K. F. Kusano, M. Taniyama, K. Nakamura, D. Miura, K. Banba, S. Nagase, H. Morita, N. Nishii, A. Watanabe, T. Tada, et al.
Atrial Fibrillation in Patients With Brugada Syndrome: Relationships of Gene Mutation, Electrophysiology, and Clinical Backgrounds
J. Am. Coll. Cardiol., March 25, 2008; 51(12): 1169 - 1175.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
P.-S. Chen and S. G. Priori
The Brugada Syndrome
J. Am. Coll. Cardiol., March 25, 2008; 51(12): 1176 - 1180.
[Full Text] [PDF]


Home page
Emerg. Med. J.Home page
S Chutani, N Imran, B Grubb, and Y Kanjwal
Propafenone-induced Brugada-like ECG changes mistaken as acute myocardial infarction
Emerg. Med. J., February 1, 2008; 25(2): 117 - 118.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
T. Ueyama, A. Shimizu, M. Esato, Y. Yoshiga, A. Sawa, S. Suzuki, N. Sugi, and M. Matsuzaki
Pilsicainide-induced Brugada-type ECG and ventricular arrhythmias originating from the left posterior fascicle in a case with Brugada syndrome associated with idiopathic left ventricular tachycardia
Europace, January 1, 2008; 10(1): 86 - 90.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
I. Six, J.-S. Hermida, H. Huang, L. Gouas, V. Fressart, N. Benammar, B. Hainque, I. Denjoy, M. Chahine, and P. Guicheney
The occurrence of Brugada syndrome and isolated cardiac conductive disease in the same family could be due to a single SCN5A mutation or to the accidental association of both diseases
Europace, January 1, 2008; 10(1): 79 - 85.
[Abstract] [Full Text] [PDF]


Home page
ANN INTERN MEDHome page
S. Kalra, S. B. Iskandar, S. Duggal, and R. D. Smalligan
Fever-Induced ST-Segment Elevation with a Brugada Syndrome-Type Electrocardiogram
Ann Intern Med, January 1, 2008; 148(1): 82 - 84.
[Full Text] [PDF]


Home page
Eur Heart J SupplHome page
R. Sutton, J. D. Fisher, C. Linde, and D. G. Benditt
History of electrical therapy for the heart
Eur. Heart J. Suppl., December 1, 2007; 9(suppl_I): I3 - I10.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart J SupplHome page
A. Sarkozy, P. Brugada, L. Mont, and J. Brugada
Optimizing the clinical use of implantable defibrillators in patients with Brugada syndrome
Eur. Heart J. Suppl., December 1, 2007; 9(suppl_I): I74 - I80.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
H. V.M. van Rijen and J. M.T. de Bakker
Penetrance of monogenetic cardiac conduction diseases. A matter of conduction reserve?
Cardiovasc Res, December 1, 2007; 76(3): 379 - 380.
[Full Text] [PDF]


Home page
CirculationHome page
S. E. Lehnart, M. J. Ackerman, D. W. Benson Jr, R. Brugada, C. E. Clancy, J. K. Donahue, A. L. George Jr, A. O. Grant, S. C. Groft, C. T. January, et al.
Inherited Arrhythmias: A National Heart, Lung, and Blood Institute and Office of Rare Diseases Workshop Consensus Report About the Diagnosis, Phenotyping, Molecular Mechanisms, and Therapeutic Approaches for Primary Cardiomyopathies of Gene Mutations Affecting Ion Channel Function
Circulation, November 13, 2007; 116(20): 2325 - 2345.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
B. London, M. Michalec, H. Mehdi, X. Zhu, L. Kerchner, S. Sanyal, P. C. Viswanathan, A. E. Pfahnl, L. L. Shang, M. Madhusudanan, et al.
Mutation in Glycerol-3-Phosphate Dehydrogenase 1-Like Gene (GPD1-L) Decreases Cardiac Na+ Current and Causes Inherited Arrhythmias
Circulation, November 13, 2007; 116(20): 2260 - 2268.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
M. A. Babai Bigi, A. Aslani, and S. Shahrzad
Clinical predictors of atrial fibrillation in Brugada syndrome
Europace, October 1, 2007; 9(10): 947 - 950.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
H. Furushima, M. Chinushi, K. Okamura, K. Iijima, S. Komura, Y. Tanabe, S. Okada, D. Izumi, and Y. Aizawa
Comparison of conduction delay in the right ventricular outflow tract between Brugada syndrome and right ventricular cardiomyopathy: investigation of signal average ECG in the precordial leads
Europace, October 1, 2007; 9(10): 951 - 956.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
C. Antzelevitch
Role of spatial dispersion of repolarization in inherited and acquired sudden cardiac death syndromes
Am J Physiol Heart Circ Physiol, October 1, 2007; 293(4): H2024 - H2038.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
M. Paul, J. Gerss, E. Schulze-Bahr, T. Wichter, C. Vahlhaus, A. A.M. Wilde, G. Breithardt, and L. Eckardt
Role of programmed ventricular stimulation in patients with Brugada syndrome: a meta-analysis of worldwide published data
Eur. Heart J., September 1, 2007; 28(17): 2126 - 2133.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
N. van Dijk, M. C. Boer, T. De Santo, N. Grovale, A. J.J. Aerts, L. Boersma, and W. Wieling
Daily, weekly, monthly, and seasonal patterns in the occurrence of vasovagal syncope in an older population
Europace, September 1, 2007; 9(9): 823 - 828.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
E. A. Stephenson and C. I. Berul
Electrophysiological Interventions for Inherited Arrhythmia Syndromes
Circulation, August 28, 2007; 116(9): 1062 - 1080.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
N. H. Robin, P. B. Tabereaux, R. Benza, and B. R. Korf
Genetic Testing in Cardiovascular Disease
J. Am. Coll. Cardiol., August 21, 2007; 50(8): 727 - 737.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
M. Hesse, C. S. Kondo, R. B. Clark, L. Su, F. L. Allen, C. T.M. Geary-Joo, S. Kunnathu, D. L. Severson, A. Nygren, W. R. Giles, et al.
Dilated cardiomyopathy is associated with reduced expression of the cardiac sodium channel Scn5a
Cardiovasc Res, August 1, 2007; 75(3): 498 - 509.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
R. K. Riezebos, K. de Man, M. S. Patterson, and G. S. de Ruiter
A bridge to Brugada
Europace, June 1, 2007; 9(6): 398 - 400.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
G. Frigo, A. Rampazzo, B. Bauce, K. Pilichou, G. Beffagna, G. A. Danieli, A. Nava, and B. Martini
Homozygous SCN5A mutation in Brugada syndrome with monomorphic ventricular tachycardia and structural heart abnormalities
Europace, June 1, 2007; 9(6): 391 - 397.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
M. M. Scheinman and E. Keung
The Year in Clinical Cardiac Electrophysiology
J. Am. Coll. Cardiol., May 22, 2007; 49(20): 2061 - 2069.
[Full Text] [PDF]


Home page
J. Physiol.Home page
K. S. Stokoe, R. Balasubramaniam, C. A. Goddard, W. H. Colledge, A. A. Grace, and C. L.-H. Huang
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/ murine hearts modelling the Brugada syndrome
J. Physiol., May 15, 2007; 581(1): 255 - 275.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
E R Behr, A Casey, M Sheppard, M Wright, T J Bowker, M J Davies, W J McKenna, and D A Wood
Sudden arrhythmic death syndrome: a national survey of sudden unexplained cardiac death
Heart, May 1, 2007; 93(5): 601 - 605.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
V. Probst, I. Denjoy, P. G. Meregalli, J.-C. Amirault, F. Sacher, J. Mansourati, D. Babuty, E. Villain, J. Victor, J.-J. Schott, et al.
Clinical Aspects and Prognosis of Brugada Syndrome in Children
Circulation, April 17, 2007; 115(15): 2042 - 2048.
[Abstract] [Full Text] [PDF]


Home page
EuropaceHome page
M. A. Babaee Bigi, A. Aslani, and S. Shahrzad
Prevalence of Brugada sign in patients presenting with palpitation in southern Iran
Europace, April 1, 2007; 9(4): 252 - 255.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
S. Basavarajaiah, A. Shah, and S. Sharma
Sudden cardiac death in young athletes
Heart, March 1, 2007; 93(3): 287 - 289.
[Abstract] [Full Text] [PDF]


Home page
Br. J. Sports. Med.Home page
H. D Esperer, O. Hoos, and K. Hottenrott
Syncope due to Brugada syndrome in a young athlete
Br. J. Sports Med., March 1, 2007; 41(3): 180 - 181.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
M. J. Junttila, M.J. P. Raatikainen, J. S. Perkiomaki, K. Hong, R. Brugada, and H. V. Huikuri
Familial clustering of lone atrial fibrillation in patients with saddleback-type ST-segment elevation in right precordial leads
Eur. Heart J., February 2, 2007; 28(4): 463 - 468.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
A. Sarkozy, T. Boussy, G. Kourgiannides, G.-B. Chierchia, S. Richter, T. De Potter, P. Geelen, F. Wellens, M. Dingena Spreeuwenberg, and P. Brugada
Long-term follow-up of primary prophylactic implantable cardioverter-defibrillator therapy in Brugada syndrome
Eur. Heart J., February 1, 2007; 28(3): 334 - 344.
[Abstract] [Full Text] [PDF]


Home page
Emerg. Med. J.Home page
M Unlu, F Bengi, B Amasyali, and S Kose
Brugada-like electrocardiographic changes induced by fever
Emerg. Med. J., January 1, 2007; 24(1): e4 - e4.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
R. Coronel, G. Berecki, and T. Opthof
Why the Brugada syndrome is not yet a disease: Syndromes, diseases, and genetic causality
Cardiovasc Res, December 1, 2006; 72(3): 361 - 363.
[Full Text] [PDF]


Home page
CirculationHome page
F. Sacher, V. Probst, Y. Iesaka, P. Jacon, J. Laborderie, F. Mizon-Gerard, P. Mabo, S. Reuter, D. Lamaison, Y. Takahashi, et al.
Outcome After Implantation of a Cardioverter-Defibrillator in Patients With Brugada Syndrome: A Multicenter Study
Circulation, November 28, 2006; 114(22): 2317 - 2324.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J. M. Cordeiro, H. Barajas-Martinez, K. Hong, E. Burashnikov, R. Pfeiffer, A.-M. Orsino, Y. S. Wu, D. Hu, J. Brugada, P. Brugada, et al.
Compound Heterozygous Mutations P336L and I1660V in the Human Cardiac Sodium Channel Associated With the Brugada Syndrome
Circulation, November 7, 2006; 114(19): 2026 - 2033.
[Abstract] [Full Text] [PDF]


Home page
AAP Grand RoundsHome page
M. Dubik
Screening for Long QT Syndrome
AAP Grand Rounds, November 1, 2006; 16(5): 49 - 50.
[Full Text] [PDF]


Home page
Eur Heart JHome page
C. Veltmann, R. Schimpf, C. Echternach, L. Eckardt, J. Kuschyk, F. Streitner, S. Spehl, M. Borggrefe, and C. Wolpert
A prospective study on spontaneous fluctuations between diagnostic and non-diagnostic ECGs in Brugada syndrome: implications for correct phenotyping and risk stratification
Eur. Heart J., November 1, 2006; 27(21): 2544 - 2552.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
Developed in Collaboration With the European Heart, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death--Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death)
J. Am. Coll. Cardiol., September 5, 2006; 48(5): 1064 - 1108.
[Full Text] [PDF]


Home page
J Am Coll CardiolHome page
Developed in Collaboration With the European Heart, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death)
J. Am. Coll. Cardiol., September 5, 2006; 48(5): e247 - e346.
[Full Text] [PDF]


Home page
Eur Heart JHome page
D. P. Zipes, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death--executive summary: A report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society.
Eur. Heart J., September 1, 2006; 27(17): 2099 - 2140.
[Full Text] [PDF]


Home page
EuropaceHome page
Writing Committee Members, D. P. Zipes, A. J. Camm, M. Borggrefe, A. E. Buxton, B. Chaitman, M. Fromer, G. Gregoratos, G. Klein, A. J. Moss, et al.
ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: A report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society
Europace, September 1, 2006; 8(9): 746 - 837.
[Full Text] [PDF]


Home page
CirculationHome page
S. Poelzing, C. Forleo, M. Samodell, L. Dudash, S. Sorrentino, M. Anaclerio, R. Troccoli, M. Iacoviello, R. Romito, P. Guida, et al.
SCN5A Polymorphism Restores Trafficking of a Brugada Syndrome Mutation on a Separate Gene
Circulation, August 1, 2006; 114(5): 368 - 376.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
A. Watanabe, K. Fukushima Kusano, H. Morita, D. Miura, W. Sumida, S. Hiramatsu, K. Banba, N. Nishii, S. Nagase, K. Nakamura, et al.
Low-dose isoproterenol for repetitive ventricular arrhythmia in patients with Brugada syndrome
Eur. Heart J., July 1, 2006; 27(13): 1579 - 1583.
[Abstract] [Full Text] [PDF]


Home page
HeartHome page
C. Wren
Screening children with a family history of sudden cardiac death.
Heart, July 1, 2006; 92(7): 1001 - 1006.
[Full Text] [PDF]


Home page
J CARDIOVASC PHARMACOL THERHome page
R. Teijeiro, H. A. Garro, R. S. Acunzo, E. Albino, and P. A. Chiale
Recording of High V1-V3 Precordial Leads May Be Essential to the Diagnosis of Brugada Syndrome During the Ajmaline Test
Journal of Cardiovascular Pharmacology and Therapeutics, June 1, 2006; 11(2): 153 - 155.
[Abstract] [PDF]


Home page
Br J AnaesthHome page
A. P. Hall and J. A. Henry
Acute toxic effects of 'Ecstasy' (MDMA) and related compounds: overview of pathophysiology and clinical management
Br. J. Anaesth., June 1, 2006; 96(6): 678 - 685.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
D. I. Keller, H. Huang, J. Zhao, R. Frank, V. Suarez, E. Delacretaz, M. Brink, S. Osswald, N. Schwick, and M. Chahine
A novel SCN5A mutation, F1344S, identified in a patient with Brugada syndrome and fever-induced ventricular fibrillation
Cardiovasc Res, June 1, 2006; 70(3): 521 - 529.