Complications of transvenous right ventricular endomyocardial biopsy in adult patients with cardiomyopathy: a seven-year survey of 546 consecutive diagnostic procedures in a tertiary referral center
JW Deckers,
JM Hare,
and
KL Baughman
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
To determine the incidence, nature and subsequent management of complications occurring during right ventricular endomyocardial biopsy in patients with cardiomyopathy, all events occurring during 546 procedures in 464 consecutive patients were prospectively recorded. The internal jugular vein was the primary site of introduction in 96% of cases. A total of 33 complications (6%) occurred: 15 (2.7%) during catheter insertion including 12 arterial punctures (2%), 2 vasovagal reactions (0.4%) and 1 episode of prolonged bleeding (0.2%), all without sequelae; 18 (3.3%) during biopsy included 6 arrhythmias (1.1%), 5 conduction abnormalities (1%), 4 possible perforations (0.7%) and 3 definite perforations (0.5%) (pericardial fluid). Two (0.4%) of the three patients with a perforation died. There was no secular trend in the complication rate, nor were complications associated with specific clinical or hemodynamic characteristics. It is concluded that the overall rate of endomyocardial biopsy complications (6%) is low, but mortality may occur.
This article has been cited by other articles:
|
|
|
|
 
M. Paul, J. Stypmann, J. Gerss, S. Wirdeier, S. Zumhagen, G. Breithardt, E. Schulze-Bahr, and T. Wichter
Safety of Endomyocardial Biopsy in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy: A Study Analyzing 161 Diagnostic Procedures
J. Am. Coll. Cardiol. Intv.,
October 1, 2011;
4(10):
1142 - 1148.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. Mahfoud, B. Gartner, M. Kindermann, C. Ukena, K. Gadomski, K. Klingel, R. Kandolf, M. Bohm, and I. Kindermann
Virus serology in patients with suspected myocarditis: utility or futility?
Eur. Heart J.,
April 1, 2011;
32(7):
897 - 903.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Yilmaz, I. Kindermann, M. Kindermann, F. Mahfoud, C. Ukena, A. Athanasiadis, S. Hill, H. Mahrholdt, M. Voehringer, M. Schieber, et al.
Comparative Evaluation of Left and Right Ventricular Endomyocardial Biopsy: Differences in Complication Rate and Diagnostic Performance
Circulation,
August 31, 2010;
122(9):
900 - 909.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Platts, M. Brown, G. Javorsky, C. West, N. Kelly, and D. Burstow
Comparison of fluoroscopic versus real-time three-dimensional transthoracic echocardiographic guidance of endomyocardial biopsies
Eur Heart J Cardiovasc Imaging,
August 1, 2010;
11(7):
637 - 643.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Mahrholdt and U. Sechtem
Noninvasive differentiation between active and healed myocarditis by cardiac magnetic resonance: are we there yet?
J. Am. Coll. Cardiol. Img.,
February 1, 2009;
2(2):
139 - 142.
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. T. Cooper Jr
Right from the heart: when should myocardial biopsy be performed for suspected arrhythmogenic right ventricular cardiomyopathy/dysplasia?
Eur. Heart J.,
November 2, 2008;
29(22):
2705 - 2707.
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Holzmann, A. Nicko, U. Kuhl, M. Noutsias, W. Poller, W. Hoffmann, A. Morguet, B. Witzenbichler, C. Tschope, H.-P. Schultheiss, et al.
Complication Rate of Right Ventricular Endomyocardial Biopsy via the Femoral Approach: A Retrospective and Prospective Study Analyzing 3048 Diagnostic Procedures Over an 11-Year Period
Circulation,
October 21, 2008;
118(17):
1722 - 1728.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
I. Kindermann, M. Kindermann, R. Kandolf, K. Klingel, B. Bultmann, T. Muller, A. Lindinger, and M. Bohm
Predictors of Outcome in Patients With Suspected Myocarditis
Circulation,
August 5, 2008;
118(6):
639 - 648.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. T. Cooper, K. L. Baughman, A. M. Feldman, A. Frustaci, M. Jessup, U. Kuhl, G. N. Levine, J. Narula, R. C. Starling, J. Towbin, et al.
The role of endomyocardial biopsy in the management of cardiovascular disease: A Scientific Statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology Endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology
Eur. Heart J.,
December 2, 2007;
28(24):
3076 - 3093.
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. T. Cooper, K. L. Baughman, A. M. Feldman, A. Frustaci, M. Jessup, U. Kuhl, G. N. Levine, J. Narula, R. C. Starling, J. Towbin, et al.
The Role of Endomyocardial Biopsy in the Management of Cardiovascular Disease: A Scientific Statement From the American Heart Association, the American College of Cardiology, and the European Society of Cardiology Endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology
J. Am. Coll. Cardiol.,
November 6, 2007;
50(19):
1914 - 1931.
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. T. Cooper, K. L. Baughman, A. M. Feldman, A. Frustaci, M. Jessup, U. Kuhl, G. N. Levine, J. Narula, R. C. Starling, J. Towbin, et al.
The Role of Endomyocardial Biopsy in the Management of Cardiovascular Disease: A Scientific Statement From the American Heart Association, the American College of Cardiology, and the European Society of Cardiology
Circulation,
November 6, 2007;
116(19):
2216 - 2233.
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. G. Assomull, J. C. Lyne, N. Keenan, A. Gulati, N. H. Bunce, S. W. Davies, D. J. Pennell, and S. K. Prasad
The role of cardiovascular magnetic resonance in patients presenting with chest pain, raised troponin, and unobstructed coronary arteries
Eur. Heart J.,
May 3, 2007;
(2007)
ehm113v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Anversa, J. Kajstura, and A. Leri
If I Can Stop One Heart From Breaking
Circulation,
February 20, 2007;
115(7):
829 - 832.
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. R. Smith, L. Barile, H. C. Cho, M. K. Leppo, J. M. Hare, E. Messina, A. Giacomello, M. R. Abraham, and E. Marban
Regenerative Potential of Cardiosphere-Derived Cells Expanded From Percutaneous Endomyocardial Biopsy Specimens
Circulation,
February 20, 2007;
115(7):
896 - 908.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. G. Assomull, S. K. Prasad, J. Lyne, G. Smith, E. D. Burman, M. Khan, M. N. Sheppard, P. A. Poole-Wilson, and D. J. Pennell
Cardiovascular Magnetic Resonance, Fibrosis, and Prognosis in Dilated Cardiomyopathy
J. Am. Coll. Cardiol.,
November 21, 2006;
48(10):
1977 - 1985.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Kilo, G. Laufer, and H. Antretter
Endomyocardial biopsy - jugular/subclavian vein approach
MMCTS,
January 1, 2006;
2006(1110):
mmcts.2005.001149 - mmcts.2005.001149.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Knaapen, R. Boellaard, M. J.W. Gotte, P. A. Dijkmans, L. M.C. van Campen, C. C. de Cock, G. Luurtsema, C. A. Visser, A. A. Lammertsma, and F. C. Visser
Perfusable Tissue Index as a Potential Marker of Fibrosis in Patients with Idiopathic Dilated Cardiomyopathy
J. Nucl. Med.,
August 1, 2004;
45(8):
1299 - 1304.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. G. Pophal, G. Sigfusson, K. L. Booth, S.-A. Bacanu, S. A. Webber, J. A. Ettedgui, W. H. Neches, and S. C. Park
Complications of endomyocardial biopsy in children
J. Am. Coll. Cardiol.,
December 1, 1999;
34(7):
2105 - 2110.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. S. M. Tsang, W. K. Freeman, M. E. Barnes, G. S. Reeder, D. L. Packer, and J. B. Seward
Rescue echocardiographically guided pericardiocentesis for cardiac perforation complicating catheter-based procedures: The Mayo Clinic experience
J. Am. Coll. Cardiol.,
November 1, 1998;
32(5):
1345 - 1350.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. B. Huddleston, M. Rosenbloom, J. A. Goldstein, and M. K. Pasque
Biopsy-induced tricuspid regurgitation after cardiac transplantation
Ann. Thorac. Surg.,
April 1, 1994;
57(4):
832 - 837.
[Abstract]
[PDF]
|
|
|
|
|
|
|
COMPLICATIONS OF MYOCARDIAL BIOPSY
Journal Watch (General),
January 17, 1992;
1992(117):
3 - 3.
[Full Text]
|
|
|
|
