|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
|
|
|
|||||||||
|
|||||||||||
|
J Am Coll Cardiol, 1991; 17:717-721 © 1991 by the American College of Cardiology Foundation |
Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892.
Alcohol has direct toxic effects on the myocardium and is associated with elevated blood pressure, but its relation to left ventricular mass independent of blood pressure level has not been assessed. Reported alcohol intake and left ventricular mass measured by echocardiography were evaluated in 1,980 men and 2,511 women 17 to 90 years of age and free of cardiovascular disease in the Framingham offspring and cohort study. The relation of reported alcohol intake to left ventricular mass was assessed by gender-specific multivariate regression analysis adjusting for age, height, body mass index, systolic blood pressure, history of hypertension and cigarette smoking. Alcohol intake was positively associated with left ventricular mass in men (p less than 0.01) but not in women (p = 0.64). When stratified by beverage type, beer and wine in both men and women and liquor in men were positively related to left ventricular mass. The lack of association of total alcohol intake to left ventricular mass in women appeared to be due to a negative association (p less than 0.01) with liquor. The strongest positive associations were with wine in men (p less than 0.001) and beer in women (p less than 0.05). Alcohol use is independently associated with left ventricular mass; this association may vary by beverage type. In persons with unexplained left ventricular hypertrophy, excessive alcohol intake should be considered.
This article has been cited by other articles:
|
|
 |
|
  M. Kannan, L. Wang, and Y. J. Kang Myocardial Oxidative Stress and Toxicity Induced by Acute Ethanol Exposure in Mice Experimental Biology and Medicine, June 1, 2004; 229(6): 553 - 559. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Kuznetsova, J. A. Staessen, A. Olszanecka, A. Ryabikov, K. Stolarz, S. Malyutina, R. Fagard, K. Kawecka-Jaszcz, and Y. Nikitin Maternal and Paternal Influences on Left Ventricular Mass of Offspring Hypertension, January 1, 2003; 41(1): 69 - 74. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. R. Walsh, M. G. Larson, J. C. Evans, L. Djousse, R. C. Ellison, R. S. Vasan, and D. Levy Alcohol Consumption and Risk for Congestive Heart Failure in the Framingham Heart Study Ann Intern Med, February 5, 2002; 136(3): 181 - 191. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O A Kajander, M Kupari, P Laippala, V Savolainen, J Pajarinen, A Penttila, and P J Karhunen Dose dependent but non-linear effects of alcohol on the left and right ventricle Heart, October 1, 2001; 86(4): 417 - 423. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Sundstrom, L. Lind, B. Vessby, B. Andren, A. Aro, and H. O. Lithell Dyslipidemia and an Unfavorable Fatty Acid Profile Predict Left Ventricular Hypertrophy 20 Years Later Circulation, February 13, 2001; 103(6): 836 - 841. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Mannami, S. Baba, and J. Ogata Potential of Carotid Enlargement as a Useful Indicator Affected by High Blood Pressure in a Large General Population of a Japanese City : The Suita Study Stroke, December 1, 2000; 31(12): 2958 - 2965. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.A. Papadakis, E.S. Ganotakis, and D.P. Mikhailidis Beneficial effect of moderate alcohol consumption on vascular disease: myth or reality? The Journal of the Royal Society for the Promotion of Health, March 1, 2000; 120(1): 11 - 15. [Abstract] [PDF]
|
|
|
|
 |
|
 H. Schirmer, P. Lunde, and K. Rasmussen Prevalence of left ventricular hypertrophy in a general population; The Tromso Study Eur. Heart J., March 2, 1999; 20(6): 429 - 438. [Abstract] [PDF]
|
|
|
|
 |
|
 R. A. Phillips, L. R. Krakoff, A. Dunaif, D. T. Finegood, R. Gorlin, and S. Shimabukuro Relation among Left Ventricular Mass, Insulin Resistance, and Blood Pressure in Nonobese Subjects J. Clin. Endocrinol. Metab., December 1, 1998; 83(12): 4284 - 4288. [Abstract] [Full Text]
|
|
|
|
|
|
M. Kupari, A. Hautanen, L. Lankinen, P. Koskinen, J. Virolainen, H. Nikkila, and P. C. White Associations Between Human Aldosterone Synthase (CYP11B2) Gene Polymorphisms and Left Ventricular Size, Mass, and Function Circulation, February 17, 1998; 97(6): 569 - 575. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Bonithon-Kopp, P. J. Touboul, C. Berr, C. Magne, and P. Ducimetiere Factors of Carotid Arterial Enlargement in a Population Aged 59 to 71 Years : The EVA Study Stroke, April 1, 1996; 27(4): 654 - 660. [Abstract] [Full Text]
|
|
|
|
|
|
J. M. Gardin, L. E. Wagenknecht, H. Anton-Culver, J. Flack, S. Gidding, T. Kurosaki, N. D. Wong, and T. A. Manolio Relationship of Cardiovascular Risk Factors to Echocardiographic Left Ventricular Mass in Healthy Young Black and White Adult Men and Women : The CARDIA Study Circulation, August 1, 1995; 92(3): 380 - 387. [Abstract] [Full Text]
|
|
|
|
|
|
P. R. Liebson, G. A. Grandits, S. Dianzumba, R. J. Prineas, R. H. Grimm Jr, J. D. Neaton, and J. Stamler Comparison of Five Antihypertensive Monotherapies and Placebo for Change in Left Ventricular Mass in Patients Receiving Nutritional-Hygienic Therapy in the Treatment of Mild Hypertension Study (TOMHS) Circulation, February 1, 1995; 91(3): 698 - 706. [Abstract] [Full Text]
|
|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
