|
|
||||||||||
|
J Am Coll Cardiol, 1990; 16:165-170 © 1990 by the American College of Cardiology Foundation |
Department of Pediatrics, Northwestern University, Children's Memorial Hospital, Chicago, Illinois 60614.
Syncope in apparently normal patients has been attributed to an inhibitory reflex originating in cardiac sensory receptors. The reflex may be elicited by upright tilt with or without isoproterenol infusion. In this study, an upright 90 degree tilt protocol was evaluated in 20 young patients aged 7 to 22 years with syncope but with normal cardiac and neurologic evaluations. The electrocardiogram and blood pressure were noninvasively recorded at 1 min intervals while the patient was supine (5 to 10 min) and during tilt (15 min) in the baseline state. The protocol was repeated during isoproterenol infusion at increasing doses until symptoms of syncope or near syncope were provoked or the maximal isoproterenol dose was achieved (0.07 to 0.1 microgram/kg per min). Mean heart rate, mean blood pressure and RR interval variability, expressed as the standard deviation and the mean of the absolute difference between consecutive RR intervals, were assessed. Symptoms were elicited during tilt in 16 of the 20 patients (in 4 at baseline and in 12 with isoproterenol infusion); no symptoms were induced in 4 patients.(ABSTRACT TRUNCATED AT 250 WORDS)
This article has been cited by other articles:
![]() |
G. Foglia-Manzillo, F. Giada, N. Fteita, I. Nessi, M. Santarone, and A. Raviele Tilt testing potentiated with sublingual nitroglycerin in children with unexplained syncope Eur. Heart J., November 1, 2007; 28(21): 2605 - 2609. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. P. Vlahos, M. Tzoufi, C. S. Katsouras, T. Barka, I. Sionti, L. K. Michalis, A. Siamopoulou, and T. M. Kolettis Provocation of Neurocardiogenic Syncope During Head-up Tilt Testing in Children: Comparison Between Isoproterenol and Nitroglycerin Pediatrics, February 1, 2007; 119(2): e419 - e425. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Raviele Tilt-induced asystole: a useful prognostic marker or clinically unrelevant finding? Eur. Heart J., March 2, 2002; 23(6): 433 - 437. [Full Text] [PDF] |
||||
![]() |
C.M. Seifer and R.A. Kenny Head-up tilt testing in children Eur. Heart J., November 1, 2001; 22(21): 1968 - 1971. [PDF] |
||||
![]() |
J Sagrista-Sauleda, B Romero-Ferrer, A Moya, G Permanyer-Miralda, and J Soler-Soler Variations in diagnostic yield of head-up tilt test and electrophysiology in groups of patients with syncope of unknown origin Eur. Heart J., May 2, 2001; 22(10): 857 - 865. [Abstract] [PDF] |
||||
![]() |
A. M. Fenton, S. C. Hammill, R. F. Rea, P. A. Low, and W.-K. Shen Vasovagal Syncope Ann Intern Med, November 7, 2000; 133(9): 714 - 725. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. P. Fitzpatrick and A. Zaidi Tilt methodology in reflex syncope: emerging evidence J. Am. Coll. Cardiol., July 1, 2000; 36(1): 179 - 180. [Full Text] [PDF] |
||||
![]() |
T. R. Burklow, J. P. Moak, J. J. Bailey, and F. T. Makhlouf Neurally mediated cardiac syncope: autonomic modulation after normal saline infusion J. Am. Coll. Cardiol., June 1, 1999; 33(7): 2059 - 2066. [Abstract] [Full Text] [PDF] |
||||
![]() |
S Oraii, M Maleki, M Minooii, and P Kafaii Comparing two different protocols for tilt table testing: sublingual glyceryl trinitrate versus isoprenaline infusion Heart, June 1, 1999; 81(6): 603 - 605. [Abstract] [Full Text] |
||||
![]() |
W.-K. Shen, A. Jahangir, D. Beinborn, C. M. Lohse, D. O. Hodge, R. F. Rea, and S. C. Hammill Utility of a single-stage isoproterenol tilt table test in adults: A randomized comparison with passive head-up tilt J. Am. Coll. Cardiol., March 15, 1999; 33(4): 985 - 990. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Sagrista-Sauleda, B. Romero, G. Permanyer-Miralda, A. Moya, T. Rius-Gelabert, L. Mont Girbau, and J. Soler-Soler Clinical usefulness of head-up tilt test in patients with syncope and intraventricular conduction defect Europace, January 1, 1999; 1(1): 63 - 68. [Abstract] [PDF] |
||||
![]() |
A. K. Younoszai, W. H. Franklin, D. P. Chan, S. C. Cassidy, and H. D. Allen Oral Fluid Therapy: A Promising Treatment for Vasodepressor Syncope Arch Pediatr Adolesc Med, February 1, 1998; 152(2): 165 - 168. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. E. Boehm, K. T. Kip, B. P. Grubb, and D. J. Kosinski Neurocardiogenic Syncope: Response to Hormonal Therapy Pediatrics, April 1, 1997; 99(4): 623 - 623. [Full Text] [PDF] |
||||
![]() |
T. Lerman-Sagie, P. Lerman, M. Mukamel, L. Blieden, and M. Mimouni A Prospective Evaluation of Pediatric Patients With Syncope Clinical Pediatrics, February 1, 1994; 33(2): 66 - 70. [Abstract] [PDF] |
||||
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |