|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
|
|
|
|||||||||
|
|||||||||||
|
J Am Coll Cardiol, 1989; 14:119-126 © 1989 by the American College of Cardiology Foundation |
Department of Internal Medicine, University of Iowa, Iowa City.
The detailed evaluation of regional diastolic filling at multiple ventricular levels in the normal human left ventricle has not previously been reported. Ultrafast computed tomography was used to characterize global and regional early diastolic filling in the left ventricle of 11 normal male volunteers. Regional early diastolic filling data from six distinct ventricular levels (apex to base) were fit to a third-order polynomial curve, and the peak rate of diastolic filling and time of peak filling were determined. Peak filling rate was 259 +/- 17 ml/s (+/- SEM) as a global average, where peak filling rate referenced to end-diastolic volume and stroke volume across the levels examined was 3.78 +/- 0.17 s-1 and 4.83 +/- 0.20 s-1, respectively. Average filling fraction was 39 +/- 1%, and time to peak filling from end-systole was 145 +/- 5 ms. Regional (tomographic) peak filling rates, except for the most apical level examined, were not statistically different across the ventricle. Filling fraction and time to peak filling were remarkably constant from one level to another. However, reference of regional peak filling rate to regional end-diastolic volume demonstrated significant nonuniformity from apex (120% of average for all levels) to base (87% of average for all levels). Peak filling rate referenced to tomographic stroke volume was less variable and not statistically different across the ventricle as a whole.(ABSTRACT TRUNCATED AT 250 WORDS)
This article has been cited by other articles:
|
|
 |
|
  E. Daghini, E. L. Ritman, and L. O. Lerman Examine Thy Heart With All Diligence: Evaluation of Cardiac Function Using Fast Computed Tomography Hypertension, February 1, 2007; 49(2): 249 - 256. [Full Text] [PDF]
|
|
|
|
 |
|
 A. Lembcke, S. Dushe, S. Sonntag, C. Kloeters, C. N. H. Enzweiler, T. H. Wiese, B. Hamm, F.-X. Kleber, and W. F. Konertz Changes in right ventricular dimensions and performance after passive cardiac containment Ann. Thorac. Surg., September 1, 2004; 78(3): 900 - 905. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. P. Katra, E. Pruvot, and K. R. Laurita Intracellular calcium handling heterogeneities in intact guinea pig hearts Am J Physiol Heart Circ Physiol, February 1, 2004; 286(2): H648 - H656. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Lembcke, S. Dushe, C. N.H. Enzweiler, C. Kloeters, T. H. Wiese, K.-G. A. Hermann, B. Hamm, and W. F. Konertz Passive external cardiac constraint improves segmental left ventricular wall motion and reduces akinetic area in patients with non-ischemic dilated cardiomyopathy Eur. J. Cardiothorac. Surg., January 1, 2004; 25(1): 84 - 90. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Hatle and G. R. Sutherland Regional myocardial function--a new approach. Eur. Heart J., August 1, 2000; 21(16): 1337 - 1357. [PDF]
|
|
|
|
 |
|
 W. Stanford and B. H. Thompson Coronary atherosclerosis and its effect on cardiac structure and function: evaluation by electron beam computed tomography Clin. Chem., August 1, 1998; 44(8): 1871 - 1881. [Abstract] [Full Text] [PDF]
|
|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |
