Importance of balloon size in coronary angioplasty

Department of Medicine, College of Physicians and Surgeons, Columbia University.

The effect of balloon size on the success of coronary angioplasty was studied to develop quantitative criteria for optimal selection of balloon size. Coronary dimensions of 165 stenotic lesions were measured by computer-assisted cinevideodensitometry in 120 patients who had undergone angioplasty with a balloon selected by visual estimates. Cross-sectional areas and diameters of normal and stenotic arterial segments were measured before and after angioplasty by a previously validated cinevideodensitometric technique. The diameter of the inflated balloon compared with that of the normal arterial segment was expressed as a ratio for sizing balloons. Oversized balloons with a ratio greater than 1.3 (n = 35) caused a high (37%) incidence of dissection, with three severely compromised arterial lumens. Undersized balloons with a ratio less than 0.9 (n = 29) often resulted in significant (greater than 50% diameter stenosis) residual stenotic lesions (21%) and a significantly (p less than 0.05) higher rate of repeat angioplasty for restenosis. Selection of balloon sizes with ratios in the 0.9 to 1.3 range (n = 101) resulted in a low (4%) incidence of dissection with few patients (3%) having significant residual stenosis. Mean residual stenosis (percent diameter reduction) was most severe for undersized (35.0 +/- 18%) or oversized (23.1 +/- 19%) balloons and least severe for balloons with a ratio of 0.9 to 1.3 (18.7 +/- 14%) (p less than 0.001). Repeat angioplasty for restenosis was more frequently required (p less than 0.05) for lesions dilated with undersized balloons. Thus, selection of angioplasty balloons that approximate or slightly exceed the diameter of the normal arterial diameter yields optimal angiographic results with minimal dissections and minimal residual stenotic lesions.

This article has been cited by other articles:

				M. Haude and R. Erbel How big is small? Eur. Heart J., February 1, 2002; 23(3): 198 - 199. [Full Text] [PDF]

				C. Briguori, J. Tobis, T. Nishida, M. Vaghetti, R. Albiero, C. Di Mario, and A. Colombo Discrepancy between angiography and intravascular ultrasound when analysing small coronary arteries Eur. Heart J., February 1, 2002; 23(3): 247 - 254. [Abstract] [Full Text] [PDF]

				R. A. M. van Liebergen, J. J. Piek, K. T. Koch, R. J. G. Peters, R. J. de Winter, C. E. Schotborgh, and K. I. Lie Hyperemic coronary flow after optimized intravascular ultrasound-guided balloon angioplasty and stent implantation J. Am. Coll. Cardiol., December 1, 1999; 34(7): 1899 - 1906. [Abstract] [Full Text] [PDF]

				C. R. Narins, D. R. Holmes Jr, and E. J. Topol A Call for Provisional Stenting : The Balloon Is Back! Circulation, April 7, 1998; 97(13): 1298 - 1305. [Full Text] [PDF]

				G. W. Stone, J. M. Hodgson, F. G. St Goar, A. Frey, H. Mudra, H. Sheehan, and T. J. Linnemeier Improved Procedural Results of Coronary Angioplasty With Intravascular Ultrasound–Guided Balloon Sizing : The CLOUT Pilot Trial Circulation, April 15, 1997; 95(8): 2044 - 2052. [Abstract] [Full Text]

				C. Landau, R. A. Lange, and L. D. Hillis Percutaneous Transluminal Coronary Angioplasty N. Engl. J. Med., April 7, 1994; 330(14): 981 - 993. [Full Text]

				K. H. Sheikh, C. J. Davidson, G. E. Newman, K. B. Kisslo, and S. J. Schwab Intravascular Ultrasound Assessment of the Renal Artery Ann Intern Med, July 1, 1991; 115(1): 22 - 25. [Abstract] [PDF]