The automatic implantable cardioverter-defibrillator: efficacy, complications and survival in patients with malignant ventricular arrhythmias
PA Kelly,
DS Cannom,
H Garan,
GS Mirabal,
JW Harthorne,
RJ Hurvitz,
GJ Vlahakes,
ML Jacobs,
JP Ilvento,
MJ Buckley,
et al.
Cardiac Unit, Massachusetts General Hospital, Boston 02114.
Ninety-four patients underwent surgery for automatic implantable cardioverter-defibrillator implantation. Ninety patients were discharged from the hospital with the device and were followed up for a mean period of 17 +/- 10 months. Forty-six patients experienced at least one discharge of the device under circumstances consistent with a malignant ventricular arrhythmia. One sudden death occurred. Complications included perioperative death (3 patients), post-operative ventricular tachycardia (12 patients) and atrial fibrillation (8 patients), perioperative myocardial infarction (1 patient) and device discharges for sinus tachycardia and supraventricular arrhythmias (17 patients). Six and 12 month survival rates by life table analysis were 98.7 and 95.4%, respectively. Thus, the automatic implantable cardioverter-defibrillator is a highly effective and relatively low risk treatment modality for patients with refractory life-threatening ventricular arrhythmias.
This article has been cited by other articles:

|
 |

|
 |
 
L. B. Mitchell, E. A. Pineda, J. L. Titus, P. M. Bartosch, and D. G. Benditt
Sudden death in patients with implantable cardioverter defibrillators: The importance of post-shock electromechanical dissociation
J. Am. Coll. Cardiol.,
April 17, 2002;
39(8):
1323 - 1328.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. R. Cartwright and L. L. Hill
Anesthesia for Insertion of Implantable Cardioverter Defibdilators
Seminars in Cardiothoracic and Vascular Anesthesia,
September 1, 2000;
4(3):
180 - 186.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Katz, R. J. Sweeney, R. M. Gill, P. R. Reid, and E. N. Prystowsky
Relation of Atrial Refractoriness to Upper and Lower Limits of Vulnerability for Atrial Fibrillation/Flutter Following Implantable Ventricular Defibrillator Shocks
Circulation,
September 7, 1999;
100(10):
1125 - 1130.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. S. Cannom and E. N. Prystowsky
Management of Ventricular Arrhythmias: Detection, Drugs, and Devices
JAMA,
January 13, 1999;
281(2):
172 - 179.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J P Bourke, A Loaiza, G Parry, C Hilton, S Furniss, J Dark, and J Forty
Role of orthotopic heart transplantation in the management of patients with recurrent ventricular tachyarrhythmias following myocardial infarction
Heart,
November 1, 1998;
80(5):
473 - 478.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
Y. Yamanouchi, K. A. Mowrey, M. J. Niebauer, P. J. Tchou, and B. L. Wilkoff
Additional Lead Improves Defibrillation Efficacy With an Abdominal `Hot Can' Electrode System
Circulation,
December 16, 1997;
96(12):
4400 - 4407.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
K. J. Quan, J. H. Lee, O. Costantini, A. K. Konstantakos, H. K. Murrell, M. D. Carlson, J. A. Mackall, L. A. Biblo, and A. S. Geha
Favorable Results of Implantable Cardioverter-Defibrillator Implantation in Patients Older Than 70 Years
Ann. Thorac. Surg.,
December 1, 1997;
64(6):
1713 - 1717.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
J. P Bourke, D. Turkington, G. Thomas, J. M McComb, and M. Tynan
Florid psychopathology in patients receiving shocks from implanted cardioverter-defibrillators
Heart,
December 1, 1997;
78(6):
581 - 583.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H.-J. Trappe, P. Pfitzner, M. Achtelik, and H.-G. Fieguth
Age dependent efficacy of implantable cardioverter-defibrillator treatment: observations in 450 patients over an 11 year period
Heart,
October 1, 1997;
78(4):
364 - 370.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. A. Strickberger, K. C. Man, E. G. Daoud, R. Goyal, K. Brinkman, C. Hasse, F. Bogun, B. P. Knight, R. Weiss, M. Bahu, et al.
A Prospective Evaluation of Catheter Ablation of Ventricular Tachycardia as Adjuvant Therapy in Patients With Coronary Artery Disease and an Implantable Cardioverter-Defibrillator
Circulation,
September 2, 1997;
96(5):
1525 - 1531.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
M. Nair, N. Saoudi, D. Kroiss, and B. Letac
Automatic Arrhythmia Identification Using Analysis of the Atrioventricular Association: Application to a New Generation of Implantable Defibrillators
Circulation,
February 18, 1997;
95(4):
967 - 973.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
J. E. Molina
Undertreatment and Overtreatment of Patients With Infected Antiarrhythmic Implantable Devices
Ann. Thorac. Surg.,
February 1, 1997;
63(2):
504 - 509.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
G. Gioia, B. Bagheri, C. D. Gottlieb, D. S. Schwartzman, D. J. Callans, F. E. Marchlinski, J. Heo, and A. E. Iskandrian
Prediction of Outcome of Patients With Life-Threatening Ventricular Arrhythmias Treated With Automatic Implantable Cardioverter-Defibrillators Using SPECT Perfusion Imaging
Circulation,
January 21, 1997;
95(2):
390 - 394.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
S. O'Nunain, I. Perez, M. Roelke, S. Osswald, B. A. McGovern, D. R. Brooks, D. F. Torchiana, G. J. Vlahakes, J. Ruskin, and H. Garan
THE TREATMENT OF PATIENTS WITH INFECTED IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR SYSTEMS
J. Thorac. Cardiovasc. Surg.,
January 1, 1997;
113(1):
121 - 129.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
A. J. Moss, W. J. Hall, D. S. Cannom, J. P. Daubert, S. L. Higgins, H. Klein, J. H. Levine, S. Saksena, A. L. Waldo, D. Wilber, et al.
Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia
N. Engl. J. Med.,
December 26, 1996;
335(26):
1933 - 1940.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. E. Epstein, W. M. Miles, D. G. Benditt, A. J. Camm, E. J. Darling, P. L. Friedman, A. Garson, J. C. Harvey, G. A. Kidwell, G. J. Klein, et al.
Personal and Public Safety Issues Related to Arrhythmias That May Affect Consciousness: Implications for Regulation and Physician Recommendations: A Medical/Scientific Statement From the American Heart Association and the North American Society of Pacing and Electrophysiology
Circulation,
September 1, 1996;
94(5):
1147 - 1166.
[Full Text]
|
 |
|

|
 |

|
 |
 
H. L. Horton, R. A. Marinchak, S. J. Rials, and P. R. Kowey
Gender Differences in Device Therapy for Malignant Ventricular Arrhythmias
Arch Intern Med,
November 27, 1995;
155(21):
2342 - 2345.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
P. C. Fotuhi, R. E. Ideker, S. F. Idriss, R. L. Callihan, R. G. Walker, and E. U. Alt
Influence of Epicardial Patches on Defibrillation Threshold With Nonthoracotomy Lead Configurations
Circulation,
November 15, 1995;
92(10):
3082 - 3088.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
S. L. Pinski and G. J. Fahy
The Proarrhythmic Potential of Implantable Cardioverter-Defibrillators
Circulation,
September 15, 1995;
92(6):
1651 - 1664.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
J. E. Molina, D. G. Benditt, and S. Adler
Crinkling of epicardial defibrillator patchesA common and serious problem
J. Thorac. Cardiovasc. Surg.,
July 1, 1995;
110(1):
258 - 264.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
D. M. Shahian, W. A. Williamson, L. G. Svensson, R. S. D'Agostino, D. T. Martin, J. R. Ellis, and F. J. Venditti
Transvenous versus transthoracic cardioverter-defibrillator implantation: A comparative analysis of morbidity, mortality, and survival
J. Thorac. Cardiovasc. Surg.,
June 1, 1995;
109(6):
1066 - 1074.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
S. O. Nunain, M. Roelke, T. Trouton, S. Osswald, Y. H. Kim, G. Sosa-Suarez, D. R. Brooks, B. McGovern, M. Guy, D. F. Torchiana, et al.
Limitations and Late Complications of Third-Generation Automatic Cardioverter-Defibrillators
Circulation,
April 15, 1995;
91(8):
2204 - 2213.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
E. U. Alt, P. C. Fotuhi, R. L. Callihan, D. L. Rollins, E. Mestre, M. P. Combs, W. M. Smith, and R. E. Ideker
Improved Defibrillation Threshold With a New Epicardial Carbon Electrode Compared With a Standard Epicardial Titanium Patch
Circulation,
January 15, 1995;
91(2):
445 - 450.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
W. H. Kou, H. Calkins, R. R. Lewis, S. F. Bolling, M. M. Kirsch, J. J. Langberg, M. de Buitleir, J. Sousa, R. El-Atassi, and F. Morady
Incidence of Loss of Consciousness during Automatic Implantable Cardioverter-Defibrillator Shocks
Ann Intern Med,
December 15, 1991;
115(12):
942 - 945.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Renzulli, A. D'Onofrio, B.E. Glenville, S. Naik, J.P. Bourke, J.M. McComb, R.W.F. Campbell, and C.J. Hilton
Surgical Treatment of Postinfarct Ventricular Tachycardia--Seven Years of Experience
Vascular and Endovascular Surgery,
May 1, 1991;
25(4):
301 - 307.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Akhtar, H. Garan, M. H. Lehmann, and P. J. Troup
Sudden Cardiac Death: Management of High-Risk Patients
Ann Intern Med,
March 15, 1991;
114(6):
499 - 512.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
R. Brooks, B. A. McGovern, H. Garan, and J. N. Ruskin
Current Treatment of Patients Surviving Out-of-Hospital Cardiac Arrest
JAMA,
February 13, 1991;
265(6):
762 - 768.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
A. S. Manolis, M. Linzer, D. Salem, and N. A. M. Estes III
Syncope: Current Diagnostic Evaluation and Management
Ann Intern Med,
June 1, 1990;
112(11):
850 - 863.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
J. M. Gore and J. E. Dalen
Cardiovascular Disease
JAMA,
May 19, 1989;
261(19):
2829 - 2831.
[Abstract]
[PDF]
|
 |
|
|