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Figure 4 Olmesartan Restores eNOS Expression in the Aortic Valve

Immunostaining for endothelial nitric oxide synthase (eNOS) in aortic valve from control (A), hypercholesterolemic (B), and hypercholesterolemic olmesartan-treated (C) rabbits. Positive staining is shown as red. Arrowheads indicate aortic side of valve leaflet. (D) Quantitation of eNOS-positive circumference corrected for total valve surface. Ao = aorta. Bar = 200 µm.