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Figure 2 Baseline and Differential Change in Venous, Pulmonary, and Arterial Pressures to BNP, SIL, or Both in Normal and Failing Heart

Bar graphs illustrating the acute change in hemodynamics to B-type natriuretic peptide (BNP), sildenafil (SIL), or the combination of SIL + BNP in normal (left) and heart failure dogs (right). *p < 0.05 versus baseline; p < 0.05 comparing SIL + BNP versus BNP alone; #p < 0.05 for the interaction between drug treatment and heart failure. CVP = central venous pressure; dPAP = diastolic pulmonary arterial pressure; MAP = mean arterial pressure; mPAP = mean pulmonary arterial pressure.