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Figure 4 Change in Mean SBP in Baseline SBP Quartiles and in Baseline SBP 100 mm Hg

In the fixed-dose combination of isosorbide dinitrate and hydralazine (FDC I/H) group, blood pressure (BP) decreased in the 2 highest systolic blood pressure (SBP) quartiles and increased in the lowest SBP quartile and in subjects with baseline systolic BP 100 mm Hg, but did not change in the second lowest SBP quartile. There were 79 subjects with baseline systolic BP 100 mm Hg (mean SBP in FDC I/H group 95.0 ± 5.0 mm Hg, n = 31, and in placebo group 95 ± 5.4 mm Hg, n = 48). The p values compare changes between treatment groups: *p < 0.05; **p < 0.01.