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Figure 1 Incremental cost-effectiveness ratios (iCERs) for various horizons, actual and projected. The iCER was estimated from the data with horizons of 1, 1.5, 2, 2.5, 3, and 3.5 years, marked by circles. The vertical line segment is a 95% confidence interval for the iCER at 3.5 years (Table 3). The other lines are iCERs derived from projected survival curves (this figure) and the regression model for costs (Fig. 2). As in Figure 2, the actual iCER values are slightly higher than the fitted model projections because early replacement costs of implantable cardioverter-defibrillators were removed when fitting the model, with all replacement costs imposed at 5 and 10 years. Note that the vertical axis has a logarithmic scale.