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Figure 2 (A) Representative Western blot autoradiogram of the 52-kDa MMP-1 protein and the 28-kDa TIMP-1 protein. Autoradiograms include endomyocardial samples from one normotensive patient, one hypertensive patient with diastolic heart failure, and one hypertensive patient with systolic heart failure. (B) Bars represent mean + SEM of the ratio of MMP- to TIMP-1, calculated in endomyocardial samples from the three groups of subjects. DHF = diastolic heart failure; HT = hypertensive; MMP = matrix metalloproteinase; NT = normotensive; SHF = systolic heart failure; TIMP = tissue inhibitor matrix metalloproteinase.