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Figure 2 Main threshold analyses. Varying left atrial catheter ablation (LACA) efficacy rates and annual stroke risks with normal sinus rhythm (NSR) restoration are determined for incremental cost-effectiveness thresholds of $50,000 (diamonds) and $100,000 (squares) per quality-adjusted life-year for 65-year-old (A) and 55-year-old (B) subjects at moderate risk for stroke. For each LACA efficacy rate, LACA would be cost-effective at a specific threshold with stroke risks at or below the threshold lines.