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Figure 5 Black box plots and hatched bars indicate recommended dosing range. (A) Simulated sotalol trough concentrations (125 patients per group and dose level) for pediatric patients with supraventricular tachycardia. Lines indicate 50% and more than 95% efficacy. (B) Patient fraction with 50% and more than 95% probability of arrhythmia suppression. Arrows indicate start and target doses.