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Figure 3


Figure 3 Effect of Pres BMT on Exercise Capacity in MI Mice

(A and B) Physical activity of BMT mice on a treadmill. Total rest time is shown in (A). Data represent the means ± SEM (n = 7). *p < 0.05 versus other groups. The distance run is shown in (B). Open triangles and closed circles represent MI-Pres BMT and MI-WT BMT, respectively. Data indicate the means ± SEM (n = 7). *p < 0.05 versus at corresponding time point. (C) Changes in tissue O2 (PtiO2) in BMT mice during hypoxia. Closed circles and open triangles indicate MI-WT and -Pres BMT mice, respectively. Data show the means ± SEM (n = 3). *p < 0.05 versus at corresponding time point. (D) Serum lactate level in BMT mice after exercise. Data represent the means ± SEM (n = 6 for MI-WT BMT mice and n = 8 for MI-Pres BMT mice). *p < 0.05. Abbreviations as in Figures 1 and 2.