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Figure 6 MT Prevents Ang II–Induced Fibrosis and Cardiac Hypertrophy

Animal treatment and tissue sampling were the same as in Figure 5. Cardiac fibrosis was examined via CTGF expression with western blotting (A) and Sirius red staining for collagen (B). (C) Atrial natriuretic peptide (ANP) messenger ribonucleic acid (mRNA); (D) - and β-MHC protein. *p < 0.05 versus corresponding control. CTGF = connective tissue growth factor; other abbreviations as in Figure 1.