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Figure 1 Programmed ICD Therapies Versus Heart Rate

(A) Cumulative percentage of patients programmed to antitachycardia pacing (ATP) and/or shock therapy (number of patients with ATP or shock therapy on at each heart rate/total number of patients in the cohort). The solid red line illustrates that nearly all PREPARE study patients had their implantable cardioverter-defibrillator (ICD) enabled to treat tachycardias >182 beats/min. In contrast, programming for the control cohort was enabled to treat slower tachycardias for the majority of patients. (B) Cumulative percentage of treated patients programmed to ATP on (number of patients with ATP programmed on at each heart rate/number of patients with ATP or shock therapy programmed on at each heart rate). The solid red line illustrates that nearly all PREPARE study patients who were programmed to be treated were programmed to be treated with ATP up to 250 beats/min. In marked contrast, a large proportion of control patients were programmed to be treated with shock, not ATP. For example, only about 40% of control patients programmed to be treated at heart rates faster than 200 beats/min were treated with ATP, while the remaining 60% were programmed to deliver shock without ATP. Bi-V = biventricular implantable cardioverter-defibrillator; bpm = beats/min.