Click on image to view larger version.

Figure 3 sTie2 Production Is Induced by VEGF In Vitro

Human umbilical vein endothelial cells were stimulated with VEGF-A₁₆₅ (25 ng/ml) for 24 h. Concentration of sTie2 in the cell-conditioned medium was quantified by enzyme-linked immunoadsorbent assay. Vascular endothelial growth factor treatment significantly increased release of sTie2 (*p < 0.01). Abbreviations as in Figure 1.