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Figure 2 Negative Interaction Between CCBs and Clopidogrel

(A) The platelet reactivity index (PRI) in the vasodilator-stimulated phosphoprotein phosphorylation assay and (B) adenosine diphosphate (ADP)-induced platelet aggregation in patients with or without calcium-channel blocker (CCB) treatment are shown. Data are presented as mean and 95% confidence intervals. *p = 0.046, **p = 0.001; patients treated with CCBs compared with patients not treated with CCBs.