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Figure 2 Carotid Ultrasound Analysis

Patients harboring the ThrIle164 allele showed a diffuse carotid atherosclerotic disease with a significantly higher incidence of atherosclerotic plaque. (A) In accordance with a more severe atherosclerotic carotid disease, intima-media thickness (IMT) was significantly higher in ThrIle164 patients. (B) Plaque composition was analyzed with integrated backscatter (IBS) ultrasound technique. Patients with Thr164Thr polymorphism presented lesions with a significantly lower IBS value in the carotid artery as an index of different plaque composition between groups with a higher presence of "soft tissue" in ThrIle164 patients. Values are reported as mean ± SD.