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Figure 1 Pedigree and Clinical Features

(A) Pedigree of the family. Phenotypic traits are designated within pedigree symbols. (B) Electrocardiograms (ECGs) obtained from the proband, IV-3, before (left panel, atrial fibrillation [AF]) and after (right panel, sinus rhythm) he underwent radiofrequency catheter ablation. (C) At rest and post-exercise ECGs recorded from the proband (IV-3) and his uncle (III-1). Exercise-induced AF for the proband and atrial tachycardia for the uncle can be observed. (D) Electrocardiograms recorded from other affected individuals. Arrows indicate P waves of premature atrial contractions (PACs) in II-3, III-1, and IV-1. III-3 and IV-4 demonstrated AF.