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Figure 2 Risk of Cancer in Statin Versus Control Cohorts for Any Given Level of On-Treatment LDL-C

Each trial is represented by an empty circle (with size proportional to its weight in the meta-regressions). The slope of the regression line represents the extent to which the incidence rate ratio for cancer depends on the on-treatment low-density lipoprotein cholesterol (LDL-C) level in the statin arms (p = 0.73 for the effect of on-treatment LDL-C on the incidence rate ratio for cancer in statin vs. control cohorts). Note the LDL-C scale on the horizontal axis.