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Figure 3 Reduction of Tissue Oxidative Stress With Minocycline Treatment

Tissue oxidative stress levels in control (n = 4) and minocycline-treated (n = 5) animals. Decreased ratio of oxidized to reduced glutathione content (glutathione disulfide [GSSG]/ glutathione [GSH]) was observed in ischemic heart tissue homogenates of minocycline-treated animals. Values are mean ± SEM. RFU = relative fluorescence units.