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Figure 2 Reduction of MMP-9 Levels in the Ischemic Region With Minocycline Treatment

(A) Representative gelatin zymography of myocardial matrix metalloproteinase (MMP)-2 and -9 levels in ischemia-reperfusion control (n = 4) and minocycline-treated (n = 5) hearts. (B) Bar graph derived from densitometric analysis of 92-kDa MMP-9 zymographic activity in control (nonischemic and ischemic) and minocycline-treated (nonischemic and ischemic) hearts regions. Values are mean ± SEM. ADU = arbitrary densitometric units.