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Figure 4 Effect of PDT on Vessel Parameters

Green bars are drug-only controls, whereas brown bars represent drug and light combination. Graphs A to D show the effects of photodynamic therapy (PDT) on plaque stenosis, plaque area, lumen area, and external elastic membrane area (n = 12 arteries/group). Note that by 28 days after treatment, PDT significantly reduced plaque percent stenosis (A), reduced plaque area (B), and increased lumen area (C) with no evidence of negative or expansive arterial remodeling (D). *p < 0.05; **p < 0.01.