JACC -- van den Borne et al. 51 (22): 2184 Figure IG2

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Figure 2 Immunohistochemical Characterization of Cell Adhesion Complex Proteins in the Remote Area

Representative images of immunostaining for β-catenin (A, B), ${gamma}$ -catenin (C, D), N-cadherin (E, F), and ${alpha}$ E-catenin (G, H) in remote parts of ruptured hearts (A, C, E, G) and control myocardial infarction (MI) hearts without rupture (B, D, F, H). Abundant and similar staining for β-catenin, ${gamma}$ -catenin, and N-cadherin was observed in the intercalated disk regions of the cardiomyocytes in infarct rupture and control MI groups. For ${alpha}$ E-catenin, abundant staining of intercalated disks between cardiomyocytes was observed in the control MI hearts (H). On the contrary, 90% of the patients from the infarct rupture group showed either weak or no detectable ${alpha}$ E-catenin staining (G).