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Figure 1 Plasma SCUBE1 and sCD40L Concentration in CAD, ACS, and Acute Stroke Patients

Plasma concentration of signal peptide–complement proteins C1r/C1s, Uegf, and Bmp1–epidermal growth factor-like domain containing protein 1 (SCUBE1) and sCD40L in cases (coronary artery disease [CAD], acute coronary syndromes [ACS], acute ischemic stroke) versus healthy control subjects (A), and in subgroup analyses (B). For SCUBE1, p < 0.01 after Bonferroni correction in ACS versus control subjects and acute ischemic stroke versus control subjects. For sCD40L, *p = 0.02, **p < 0.01 after Bonferroni correction. LAT = large-vessel atherothrombotic; NSTEMI = non–ST-segment elevation myocardial infarction; SL = small lacunar stroke; STEMI = ST-segment elevation myocardial infarction; TIA = transient ischemic attack; UA = unstable angina; VD = vessel-disease.